Search Results - "Conly, J."

Proposal for an updated taxonomy for isolation precautions in healthcare facilities: the term ‘droposol’ by Widmer, A.F., Conly, J., Sommerstein, R.

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Cleaning and disinfecting surfaces in hospitals and long-term care facilities for reducing hospital- and facility-acquired bacterial and viral infections: a systematic review by Thomas, R.E., Thomas, B.C., Conly, J., Lorenzetti, D.

“…Multiply drug-resistant organisms (MDROs) in hospitals and long-term care facilities (LTCFs) of particular concern include meticillin-resistant Staphylococcus…”
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Robust epidemiological investigations in hospital-based COVID-19 outbreaks cannot be overlooked–even in the era of whole-genome sequencing by O'Grady, H.M., Harrison, R., Conly, J.M.

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Hospital and long-term care facility environmental service workers' training, skills, activities and effectiveness in cleaning and disinfection: a systematic review by Thomas, R.E., Thomas, B.C., Lorenzetti, D., Conly, J.

“…Multi-drug-resistant organisms (MDROs) (meticillin-resistant Staphylococcus aureus, vancomycin-resistant enterococcus, MDR Acinetobacter spp.,…”
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Response to a Letter to the Editor concerning a recent systematic review on cleaning and disinfecting surfaces in hospitals and long-term care facilities by Thomas, R.E., Thomas, B.C., Lorenzetti, D., Conly, J.

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Epidemiology and impact of methicillin-sensitive Staphylococcus aureus with β-lactam antibiotic inoculum effects in adults with cystic fibrosis by Svishchuk, J, Ebbert, K, Waddell, B, Izydorczyk, C, Acosta, N, Somayaji, R, Rabin, H R, Bjornson, C L, Lisboa, L, Gregson, D B, Conly, J M, Surette, M G, Parkins, M D

“…is the most prevalent cystic fibrosis (CF) pathogen. Several phenotypes are associated with worsened CF clinical outcomes including methicillin-resistance and…”
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Colistin-Nonsusceptible Pseudomonas aeruginosa Sequence Type 654 with blaNDM-1 Arrives in North America by Mataseje, L F, Peirano, G, Church, D L, Conly, J, Mulvey, M, Pitout, J D

“…This study describes 3 different blaNDM-1 genetic platforms in 3 different species obtained from the same patient who was directly transferred to an…”
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Predictors of mortality and length of stay in patients with hospital-acquired Clostridioides difficile infection: a population-based study in Alberta, Canada by Leal, J., Ronksley, P., Henderson, E.A., Conly, J., Manns, B.

“…In a population-based, five-year retrospective cohort study of 5304 adult patients with hospital-acquired Clostridioides difficile infection across Alberta…”
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Viral cultures, cycle threshold values and viral load estimation for assessing SARS-CoV-2 infectiousness in haematopoietic stem cell and solid organ transplant patients: a systematic review by Jefferson, T., Spencer, E.A., Conly, J.M., Rosca, E.C., Maltoni, S., Brassey, J., Onakpoya, I.J., Evans, D.H., Heneghan, C.J., Plüddemann, A.

“…Solid organ and haematopoietic stem cell transplant recipients are more vulnerable to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) than…”
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Viral cultures for assessing fomite transmission of SARS-CoV-2: a systematic review and meta-analysis by Onakpoya, I.J., Heneghan, C.J., Spencer, E.A., Brassey, J., Rosca, E.C., Maltoni, S., Plüddemann, A., Evans, D.H., Conly, J.M., Jefferson, T.

“…The role of fomites in the transmission of SARS-CoV-2 is unclear. To assess whether SARS-CoV-2 can be transmitted through fomites, using evidence from viral…”
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Efficacy of statins for primary prevention in people at low cardiovascular risk: a meta-analysis by Tonelli, Marcello, Lloyd, Anita, Clement, Fiona, Conly, Jon, Husereau, Don, Hemmelgarn, Brenda, Klarenbach, Scott, McAlister, Finlay A, Wiebe, Natasha, Manns, Braden

“…Statins were initially used to improve cardiovascular outcomes in people with established coronary artery disease, but recently their use has become more…”
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The development and application of a molecular community profiling strategy to identify polymicrobial bacterial DNA in the whole blood of septic patients by Faria, M M P, Conly, J M, Surette, M G

“…The application of molecular based diagnostics in sepsis has had limited success to date. Molecular community profiling methods have indicated that…”
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Determination of SARS-CoV-2 Contamination in a Neonatal Intensive Care Unit (NICU) Environment Using Droplet Digital PCR (ddPCR) by Vayalumkal, J., Pillai, D., Oberding, L., Ward, L., Fonseca, K., Mehrem, A. Abou, Conly, J.

“…Neonatal infections with SARS-CoV-2 are thought to be less contagious than in older children and adults. The transmission of SARS-CoV-2 from neonates and their…”
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Molecular epidemiology of vancomycin-resistant enterococcal bacteraemia: results from the Canadian Nosocomial Infection Surveillance Program, 1999-2009 by McCracken, M, Wong, A, Mitchell, R, Gravel, D, Conly, J, Embil, J, Johnston, L, Matlow, A, Ormiston, D, Simor, A E, Smith, S, Du, T, Hizon, R, Mulvey, M R

“…Vancomycin-resistant enterococci (VRE) can be associated with serious bacteraemia. The focus of this study was to characterize the molecular epidemiology of…”
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A two-ward acute care hospital outbreak of SARS-CoV-2 delta variant including a point-source outbreak associated with the use of a mobile vital signs cart and sub-optimal doffing of personal protective equipment by O'Grady, H.M., Harrison, R., Snedeker, K., Trufen, L., Yue, P., Ward, L., Fifen, A., Jamieson, P., Weiss, A., Coulthard, J., Lynch, T., Croxen, M.A., Li, V., Pabbaraju, K., Wong, A., Zhou, H.Y., Dingle, T.C., Hellmer, K., Berenger, B.M., Fonseca, K., Lin, Y-C., Evans, D., Conly, J.M.

“…The arrival of the Delta variant of SARS-CoV-2 was associated with increased transmissibility and illness of greater severity. Reports of nosocomial outbreaks…”
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Clinical outcomes in patients admitted to a hospitalist service exposed to an antimicrobial stewardship program - a retrospective matched cohort study by Rennert-May, E, Conly, J, Chen, G, Dalton, B

“…Given global issues with antimicrobial resistance and a need to optimize antimicrobial usage, antimicrobial stewardship (AS) programs are becoming a necessary…”
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Tyrosine 110 Plays a Critical Role in Regulating the Allosteric Inhibition of Campylobacter jejuni Dihydrodipicolinate Synthase by Lysine by Conly, Cuylar J. T, Skovpen, Yulia V, Li, Shuo, Palmer, David R. J, Sanders, David A. R

“…Dihydrodipicolinate synthase (DHDPS), an enzyme found in most bacteria and plants, controls a critical step in the biosynthesis of l-lysine and…”
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Biomimetic Design Results in a Potent Allosteric Inhibitor of Dihydrodipicolinate Synthase from Campylobacter jejuni by Skovpen, Yulia V, Conly, Cuylar J. T, Sanders, David A. R, Palmer, David R. J

“…Dihydrodipicolinate synthase (DHDPS), an enzyme required for bacterial peptidoglycan biosynthesis, catalyzes the condensation of pyruvate and β-aspartate…”
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Rationale and development of a business case for antimicrobial stewardship programs in acute care hospital settings by Morris, A M, Rennert-May, E, Dalton, B, Daneman, N, Dresser, L, Fanella, S, Grant, J, Keynan, Y, Le Saux, N, McDonald, J, Shevchuk, Y, Thirion, D, Conly, J M

“…Antimicrobial stewardship programs (ASPs) have been shown to reduce inappropriate antimicrobial use and its consequences. However, these programs lack…”
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Unusual Legionnaires' outbreak in cool, dry Western Canada: an investigation using genomic epidemiology by KNOX, N. C., WEEDMARK, K. A., CONLY, J., ENSMINGER, A. W., HOSEIN, F. S., DREWS, S. J.

“…An outbreak of Legionnaires' disease occurred in an inner city district in Calgary, Canada. This outbreak spanned a 3-week period in November–December 2012,…”
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