Search Results - "Conlon, Tj"

B-Cell Depletion is Protective Against Anti-AAV Capsid Immune Response: A Human Subject Case Study by Corti, M, Elder, Me, Falk, Dj, Lawson, L, Smith, Bk, Nayak, S, Conlon, Tj, Clément, N, Erger, K, Lavassani, E, Green, M, Doerfler, Pa, Herzog, Rw, Byrne, Bj

“…Gene therapy strategies for congenital myopathies may require repeat administration of adeno-associated viral (AAV) vectors in response to several limitations…”
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Reduced retinal transduction and enhanced transgene-directed immunogenicity with intravitreal delivery of rAAV following posterior vitrectomy in dogs by Boyd, R F, Boye, S L, Conlon, T J, Erger, K E, Sledge, D G, Langohr, I M, Hauswirth, W W, Komáromy, A M, Boye, S E, Petersen-Jones, S M, Bartoe, J T

“…Adeno-associated virus (AAV) vector-based gene therapy is a promising treatment strategy for delivery of neurotrophic transgenes to retinal ganglion cells…”
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Targeting recombinant adeno-associated virus vectors to enhance gene transfer to pancreatic islets and liver by LOILER, S. A, CONLON, T. J, MUZYCZKA, N, FLOTTE, T. R, SONG, S, TANG, Q, WARRINGTON, K. H, AGARWAL, A, KAPTURCZAK, M, LI, C, RICORDI, C, ATKINSON, M. A

“…Human pancreatic islet cells and hepatocytes represent the two most likely target cells for genetic therapy of type I diabetes. However, limits to the…”
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Recombinant adeno-associated virus vectors for gene therapy by Conlon, Thomas J, Flotte, Terence R

“…Recombinant adeno-associated virus (rAAV) vectors are based on a non-pathogenic human parvovirus (AAV) that is unique in its ability to persist in human cells…”
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B-Cell Ablation is Protective Against Anti-AAV Capsid Immune Response: A Human Subject Case Study by Corti, M, Elder, ME, Falk, DJ, Lawson, L, Smith, BK, Nayak, S, Conlon, TJ, Clement, N, Erger, K, Lavassani, E, Green, M, Er, PAD, Herzog, RW, Byrne, BJ

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Systemic correction of a fatty acid oxidation defect by intramuscular injection of a recombinant adeno-associated virus vector by Conlon, Thomas J, Walter, Glenn, Owen, Renius, Cossette, Travis, Erger, Kirsten, Gutierrez, Greg, Goetzman, Eric, Matern, Dietrich, Vockley, Jerry, Flotte, Terence R

“…Mitochondrial beta-oxidation of fatty acids is required to meet physiologic energy requirements during illness and periods of fasting or physiologic stress,…”
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Gene Therapy for Pyruvate Dehydrogenase E1α Deficiency Using Recombinant Adeno-Associated Virus 2 (rAAV2) Vectors by Owen, Renius, Mandel, Ronald J., Ammini, Chandramohan V., Conlon, Thomas J., Kerr, Douglas S., Stacpoole, Peter W., Flotte, Terence R.

“…To determine the feasibility of gene transfer to correct defects in the E1α subunit of the pyruvate dehydrogenase (PDH) complex (PDC), we constructed rAAV…”
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Evaluation of a fertilized 3-pasture system grazed by yearling steers [North Dakota] by Nyren, Paul E., Whitman, Warren C., Nelson, James L., Conlon, Thomas J.

“…A grazing trial comparing fertilized and unfertilized 3-pasture systems has shown that the addition of 56 kg nitrogen (N)/ha substantially improved forage and…”
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