Search Results - "Conley, Emily Drabant"

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    Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways by Lam, Max, Hill, W. David, Trampush, Joey W., Yu, Jin, Knowles, Emma, Davies, Gail, Stahl, Eli, Huckins, Laura, Liewald, David C., Djurovic, Srdjan, Melle, Ingrid, Sundet, Kjetil, Christoforou, Andrea, Reinvang, Ivar, DeRosse, Pamela, Lundervold, Astri J., Steen, Vidar M., Espeseth, Thomas, Räikkönen, Katri, Widen, Elisabeth, Palotie, Aarno, Eriksson, Johan G., Giegling, Ina, Konte, Bettina, Hartmann, Annette M., Roussos, Panos, Giakoumaki, Stella, Burdick, Katherine E., Payton, Antony, Ollier, William, Chiba-Falek, Ornit, Attix, Deborah K., Need, Anna C., Cirulli, Elizabeth T., Voineskos, Aristotle N., Stefanis, Nikos C., Avramopoulos, Dimitrios, Hatzimanolis, Alex, Arking, Dan E., Smyrnis, Nikolaos, Bilder, Robert M., Freimer, Nelson A., Cannon, Tyrone D., London, Edythe, Poldrack, Russell A., Sabb, Fred W., Congdon, Eliza, Conley, Emily Drabant, Scult, Matthew A., Dickinson, Dwight, Straub, Richard E., Donohoe, Gary, Morris, Derek, Corvin, Aiden, Gill, Michael, Hariri, Ahmad R., Weinberger, Daniel R., Pendleton, Neil, Bitsios, Panos, Rujescu, Dan, Lahti, Jari, Le Hellard, Stephanie, Keller, Matthew C., Andreassen, Ole A., Deary, Ian J., Glahn, David C., Malhotra, Anil K., Lencz, Todd

    Published in American journal of human genetics (01-08-2019)
    “…Susceptibility to schizophrenia is inversely correlated with general cognitive ability at both the phenotypic and the genetic level. Paradoxically, a modest…”
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    Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets by Lam, Max, Trampush, Joey W., Yu, Jin, Knowles, Emma, Davies, Gail, Liewald, David C., Starr, John M., Djurovic, Srdjan, Melle, Ingrid, Sundet, Kjetil, Christoforou, Andrea, Reinvang, Ivar, DeRosse, Pamela, Lundervold, Astri J., Steen, Vidar M., Espeseth, Thomas, Räikkönen, Katri, Widen, Elisabeth, Palotie, Aarno, Eriksson, Johan G., Giegling, Ina, Konte, Bettina, Roussos, Panos, Giakoumaki, Stella, Burdick, Katherine E., Payton, Antony, Ollier, William, Chiba-Falek, Ornit, Attix, Deborah K., Need, Anna C., Cirulli, Elizabeth T., Voineskos, Aristotle N., Stefanis, Nikos C., Avramopoulos, Dimitrios, Hatzimanolis, Alex, Arking, Dan E., Smyrnis, Nikolaos, Bilder, Robert M., Freimer, Nelson A., Cannon, Tyrone D., London, Edythe, Poldrack, Russell A., Sabb, Fred W., Congdon, Eliza, Conley, Emily Drabant, Scult, Matthew A., Dickinson, Dwight, Straub, Richard E., Donohoe, Gary, Morris, Derek, Corvin, Aiden, Gill, Michael, Hariri, Ahmad R., Weinberger, Daniel R., Pendleton, Neil, Bitsios, Panos, Rujescu, Dan, Lahti, Jari, Le Hellard, Stephanie, Keller, Matthew C., Andreassen, Ole A., Deary, Ian J., Glahn, David C., Malhotra, Anil K., Lencz, Todd

    Published in Cell reports (Cambridge) (28-11-2017)
    “…Here, we present a large (n = 107,207) genome-wide association study (GWAS) of general cognitive ability (“g”), further enhanced by combining results with a…”
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    Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics by Lam, Max, Chen, Chia-Yen, Ge, Tian, Xia, Yan, Hill, David W, Trampush, Joey W, Yu, Jin, Knowles, Emma, Davies, Gail, Stahl, Eli A, Huckins, Laura, Liewald, David C, Djurovic, Srdjan, Melle, Ingrid, Christoforou, Andrea, Reinvang, Ivar, DeRosse, Pamela, Lundervold, Astri J, Steen, Vidar M, Espeseth, Thomas, Räikkönen, Katri, Widen, Elisabeth, Palotie, Aarno, Eriksson, Johan G, Giegling, Ina, Konte, Bettina, Hartmann, Annette M, Roussos, Panos, Giakoumaki, Stella, Burdick, Katherine E, Payton, Antony, Ollier, William, Chiba-Falek, Ornit, Koltai, Deborah C, Need, Anna C, Cirulli, Elizabeth T, Voineskos, Aristotle N, Stefanis, Nikos C, Avramopoulos, Dimitrios, Hatzimanolis, Alex, Smyrnis, Nikolaos, Bilder, Robert M, Freimer, Nelson B, Cannon, Tyrone D, London, Edythe, Poldrack, Russell A, Sabb, Fred W, Congdon, Eliza, Conley, Emily Drabant, Scult, Matthew A, Dickinson, Dwight, Straub, Richard E, Donohoe, Gary, Morris, Derek, Corvin, Aiden, Gill, Michael, Hariri, Ahmad R, Weinberger, Daniel R, Pendleton, Neil, Bitsios, Panos, Rujescu, Dan, Lahti, Jari, Le Hellard, Stephanie, Keller, Matthew C, Andreassen, Ole A, Deary, Ian J, Glahn, David C, Huang, Hailiang, Liu, Chunyu, Malhotra, Anil K, Lencz, Todd

    Published in Neuropsychopharmacology (New York, N.Y.) (01-09-2021)
    “…Broad-based cognitive deficits are an enduring and disabling symptom for many patients with severe mental illness, and these impairments are inadequately…”
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    Interactions Between Anandamide and Corticotropin-Releasing Hormone Signaling Modulate Human Amygdala Function and Risk for Anxiety Disorders: An Imaging Genetics Strategy for Modeling Molecular Interactions by Demers, Catherine H, Drabant Conley, Emily, Bogdan, Ryan, Hariri, Ahmad R

    Published in Biological psychiatry (1969) (05-01-2016)
    “…Abstract Background Preclinical models reveal that stress-induced amygdala activity and impairment in fear extinction reflect reductions in anandamide driven…”
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    PER1 rs3027172 Genotype Interacts with Early Life Stress to Predict Problematic Alcohol Use, but Not Reward-Related Ventral Striatum Activity by Baranger, David A A, Ifrah, Chloé, Prather, Aric A, Carey, Caitlin E, Corral-Frías, Nadia S, Drabant Conley, Emily, Hariri, Ahmad R, Bogdan, Ryan

    Published in Frontiers in psychology (31-03-2016)
    “…Increasing evidence suggests that the circadian and stress regulatory systems contribute to alcohol use disorder (AUD) risk, which may partially arise through…”
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    Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence by Savage, Jeanne E., Jansen, Philip R., Stringer, Sven, Bryois, Julien, Nagel, Mats, Awasthi, Swapnil, Barr, Peter B., Coleman, Jonathan R. I., Grasby, Katrina L., Hammerschlag, Anke R., Kaminski, Jakob A., Karlsson, Robert, Krapohl, Eva, Lam, Max, Nygaard, Marianne, Trampush, Joey W., Young, Hannah, Zabaneh, Delilah, Hägg, Sara, Hansell, Narelle K., Linnarsson, Sten, Montgomery, Grant W., Muñoz-Manchado, Ana B., Quinlan, Erin B., Schumann, Gunter, Webb, Bradley T., White, Tonya, Arking, Dan E., Avramopoulos, Dimitrios, Bilder, Robert M., Bitsios, Panos, Burdick, Katherine E., Cannon, Tyrone D., Christoforou, Andrea, Cirulli, Elizabeth T., Congdon, Eliza, Corvin, Aiden, Davies, Gail, Deary, Ian J., DeRosse, Pamela, Dickinson, Dwight, Djurovic, Srdjan, Donohoe, Gary, Eriksson, Johan G., Espeseth, Thomas, Freimer, Nelson A., Gill, Michael, Glahn, David C., Hariri, Ahmad R., Hatzimanolis, Alex, Keller, Matthew C., Knowles, Emma, Koltai, Deborah, Konte, Bettina, Lahti, Jari, Le Hellard, Stephanie, London, Edythe, Lundervold, Astri J., Malhotra, Anil K., Melle, Ingrid, Morris, Derek, Need, Anna C., Ollier, William, Palotie, Aarno, Payton, Antony, Poldrack, Russell A., Räikkönen, Katri, Reinvang, Ivar, Roussos, Panos, Sabb, Fred W., Scult, Matthew A., Smeland, Olav B., Smyrnis, Nikolaos, Starr, John M., Steen, Vidar M., Stefanis, Nikos C., Straub, Richard E., Sundet, Kjetil, Tiemeier, Henning, Voineskos, Aristotle N., Weinberger, Daniel R., Abecasis, Goncalo, Andreassen, Ole A., Breen, Gerome, Christiansen, Lene, Debrabant, Birgit, Dick, Danielle M., Heinz, Andreas, Hjerling-Leffler, Jens, Kendler, Kenneth S., Medland, Sarah E., Pedersen, Nancy L., Plomin, Robert, Polderman, Tinca J. C., Ripke, Stephan, van der Sluis, Sophie, Sullivan, Patrick F., Vrieze, Scott I., Wright, Margaret J., Posthuma, Danielle

    Published in Nature genetics (01-07-2018)
    “…Intelligence is highly heritable 1 and a major determinant of human health and well-being 2 . Recent genome-wide meta-analyses have identified 24 genomic loci…”
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    Nonsteroidal Anti‐inflammatory Use and LRRK2 Parkinson's Disease Penetrance by San Luciano, Marta, Tanner, Caroline M., Meng, Cheryl, Marras, Connie, Lang, Anthony E., Schüle, Birgitt, Langston, J. William, Corvol, Jean‐Christophe, Goldwurm, Stefano, Berg, Daniela, Tazir, Meriem, Mellick, George D., Sue, Carolyn M., Tan, Eng King, Bressman, Susan, Saunders‐Pullman, Rachel, Raymond, Deborah, Barrett, Matthew James, Cabassa, Jose, Groves, Mark, Hunt, Ann L, Lubarr, Naomi, Palmese, Christina, Sachdev, Rivka, Sarva, Harini, Shanker, Vicki, Swan, Matthew Carrington, Soto‐Valencia, Jeannie, Johannes, Brooke, Ortega, Robert, Alcalay, Roy N, Tang, Ming‐X, Santana, Helen Mejia, Orbe‐Reilly, Martha, Fahn, Stanley, Cote, Lucien, Ford, Blair, Louis, Elan, Levy, Oren, Rosado, Llency, Ruiz, Diana, Clark, Lorraine, Marder, Karen S, Corvol, Jean‐Christophe, Bonnet, Anne‐Marie, Welter, Marie‐Laure, Mesnage, Valerie, Vidailhet, Marie, Roze, Emmanuel, Lacomblez, Lucette, Grabli, David, Mart i Masso, Jose Felix, Mondragon Rezola, Elisabet, Alustiza, Ainara Estanga, Pagola, Ana Gorostidi, Pont‐Sunyer, Claustre, Rolan, Dolores Vilas, Fernandez‐Santiago, Ruben, Quintana, Maria, Maragall, Laura, Hentati, Faycal, Farrer, Matthew, Duda, John, Read, Matt, Gibson, Rachel, Sassi, Samia Ben, Zouari, Mourad, Nabli, Fatma, Aasly, Jan, Andersen, Sigrid, Bertoni, John, Carter, Julie, Elmer, Lawrence, Jimenez, Nestor Galvez, Martin, Wayne, Pahwa, Rajesh, Lyons, Kelly, Reich, Stephen, Ramos, Carmen Serrano, Wojcieszek, Joanne, Gurevich, Tanya, Shira, Anat Bar, Weisz, Mali Gana, Yasinovsky, Kira, Zalis, Maayan, Thaler, Avner, Orr‐Urtreger, Avi, Giladi, Nir, Mountain, Joanna, Mestre, Tiago, Ghate, Taneera, Singerman, Jennifer, Al Dakheel, Amaal, Connolly, Barbara S, Gasser, Thomas, Brockmann, Kathrin, Mullins, Meghan E, Northover, Carrie, Facheris, Maurizio, Fiske, Brian

    Published in Movement disorders (01-10-2020)
    “…Background The penetrance of leucine rich repeat kinase 2 (LRRK2) mutations is incomplete and may be influenced by environmental and/or other genetic factors…”
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    Hypothalamic-Pituitary-Adrenal Axis Genetic Variation and Early Stress Moderates Amygdala Function by Iorio, Christina R. Di, Carey, Caitlin E, Michalski, Lindsay J, Corral-Frias, Nadia S, Conley, Emily Drabant, Hariri, Ahmad R, Bogdan, Ryan

    Published in Psychoneuroendocrinology (01-06-2017)
    “…Highlights • HPA axis genetic profile and early life stress interact to predict amygdala function. • HPA axis genetic profile is associated with anxiety…”
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    Effects of Schizophrenia Polygenic Risk Scores on Brain Activity and Performance During Working Memory Subprocesses in Healthy Young Adults by Miller, Jacob A, Scult, Matthew A, Conley, Emily Drabant, Chen, Qiang, Weinberger, Daniel R, Hariri, Ahmad R

    Published in Schizophrenia bulletin (06-06-2018)
    “…Abstract Recent work has begun to shed light on the neural correlates and possible mechanisms of polygenic risk for schizophrenia. Here, we map a schizophrenia…”
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    Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders by Arloth, Janine, Bogdan, Ryan, Weber, Peter, Frishman, Goar, Menke, Andreas, Wagner, Klaus V., Schmidt, Mathias V., Karbalai, Nazanin, Czamara, Darina, Altmann, Andre, Trümbach, Dietrich, Wurst, Wolfgang, Mehta, Divya, Carey, Caitlin E., Conley, Emily Drabant, Ripke, Stephan, Wray, Naomi R., Lewis, Cathryn M., Hamilton, Steven P., Blackwood, Douglas H.R., Boomsma, Dorret I., Cichon, Sven, Heath, Andrew C., Holsboer, Florian, Muglia, Pierandrea, Noethen, Markus M., Penninx, Brenda P., Pergadia, Michele L., Potash, James B., Lin, Danyu, Müller-Myhsok, Bertram, Shi, Jianxin, Steinberg, Stacy, Grabe, Hans J., Lichtenstein, Paul, Perlis, Roy H., Preisig, Martin, Smoller, Jordan W., Kutalik, Zoltan, Tansey, Katherine E., Teumer, Alexander, Bettecken, Thomas, Binder, Elisabeth B., Breuer, René, Castro, Victor M., Coryell, William H., Craddock, Nick, Czamara, Darina, Degenhardt, Franziska, Fava, Maurizio, Frank, Josef, Gainer, Vivian S., Gallagher, Patience J., Gordon, Scott D., Goryachev, Sergey, Guipponi, Michel, Henders, Anjali K., Hickie, Ian B., Hottenga, Jouke Jan, Jones, Ian, Jones, Lisa, Jung-Ying, Tzeng, Knowles, James A., Kohane, Isaac S., Kohli, Martin A., Korszun, Ania, Landen, Mikael, Lawson, William B., Lewis, Glyn, MacIntyre, Donald, Maier, Wolfgang, Mattheisen, Manuel, McGrath, Patrick J., McIntosh, Andrew, McLean, Alan, Montgomery, Grant M., Murphy, Shawn N., Nauck, Matthias, O’Donovan, Michael, Oskarsson, Högni, Pedersen, Nancy, Schulz, Andrea, Schulze, Thomas G., Shyn, Stanley I., Sigurdsson, Engilbert, Slager, Susan L., Smit, Johannes H., Stefansson, Hreinn, Steffens, Michael, Tozzi, Federica, Treutlein, Jens, Völzke, Henry, Weilburg, Jeffrey B., Willemsen, Gonneke, Neale, Benjamin, Daly, Mark, Levinson, Douglas F., Müller-Myhsok, Bertram, Hariri, Ahmad R., Binder, Elisabeth B.

    Published in Neuron (Cambridge, Mass.) (03-06-2015)
    “…Depression risk is exacerbated by genetic factors and stress exposure; however, the biological mechanisms through which these factors interact to confer…”
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    A Common Polymorphism in SCN2A Predicts General Cognitive Ability through Effects on PFC Physiology by Scult, Matthew A, Trampush, Joey W, Zheng, Fengyu, Conley, Emily Drabant, Lencz, Todd, Malhotra, Anil K, Dickinson, Dwight, Weinberger, Daniel R, Hariri, Ahmad R

    Published in Journal of cognitive neuroscience (01-09-2015)
    “…Here we provide novel convergent evidence across three independent cohorts of healthy adults (n = 531), demonstrating that a common polymorphism in the gene…”
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    Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function by Hagenaars, Saskia P., Liewald, David C. M., Ahola-Olli, Ari V., Barnes, Catriona L. K., Bertram, Lars, Bis, Joshua C., Burdick, Katherine E., Christoforou, Andrea, Espeseth, Thomas, Giakoumaki, Stella, Giddaluru, Sudheer, Gustavson, Daniel E., Lahti, Jari, Leber, Markus, Melle, Ingrid, Oldmeadow, Christopher, Reynolds, Chandra A., Scholz, Markus, Smith, Jennifer A., Smith, Albert V., Thalamuthu, Anbupalam, Trompet, Stella, van der Lee, Sven J., Ware, Erin B., Yang, Jingyun, Ames, David, Armstrong, Nicola J., Assareh, Amelia A., Böhmer, Anne C., Campbell, Harry, Cannon, Tyrone D., Corley, Janie, Cox, Simon R., Dale, Anders M., Dick, Danielle, Evangelou, Evangelos, Faul, Jessica D., Ford, Ian, Gao, He, Giegling, Ina, Gillespie, Nathan A., Gordon, Scott D., Gottesman, Rebecca F., Griswold, Michael E., Hatzimanolis, Alex, Heiss, Gerardo, Joshi, Peter K., Kähönen, Mika, Kleineidam, Luca, Kochan, Nicole A., Le Hellard, Stephanie, Lee, Teresa, Lill, Christina M., Longstreth, Will T., Lopez, Oscar L., Loukola, Anu, Lyytikäinen, Leo-Pekka, Martin, Nicholas G., Murray, Alison D., Need, Anna C., Ollier, William, Polasek, Ozren, Riedel-Heller, Steffi G., Rose, Richard J., Rovio, Suvi P., Schmid, Matthias, Scott, Rodney J., Scult, Matthew A., Simino, Jeannette, Straub, Richard E., Tzoulaki, Ioanna, Uitterlinden, André, Vitart, Veronique, Wagner, Michael, Weinhold, Leonie, Wen, K. Hoyan, Adams, Hieab H. H., Arking, Dan E., Chiba-Falek, Ornit, Debette, Stéphanie, Donohoe, Gary, Elliott, Paul, Gill, Michael, Hägg, Sara, Hansell, Narelle K., Vuoksimaa, Eero, Pendleton, Neil, Porteous, David J., Rudan, Igor, Dan Rujescu, Schmidt, Reinhold, Schofield, Peter W., Steen, Vidar M., Van Duijn, Cornelia M., Villringer, Arno, Weinberger, Daniel R., McIntosh, Andrew M., Gale, Catharine R., Mosley, Thomas H., Lencz, Todd

    Published in Nature communications (01-05-2019)
    “…Christina M. Lill, who contributed to analysis of data, was inadvertently omitted from the author list in the originally published version of this article…”
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