Search Results - "Conley, D B."

Short‐chain fatty acids induce tissue plasminogen activator in airway epithelial cells via GPR41&43 by Imoto, Y., Kato, A., Takabayashi, T., Sakashita, M., Norton, J. E., Suh, L. A., Carter, R. G., Weibman, A. R., Hulse, K. E., Stevens, W., Harris, K. E., Peters, A. T., Grammer, L. C., Tan, B. K., Welch, K., Conley, D. B., Kern, R. C., Fujieda, S., Schleimer, R. P.

“…Summary Background Chronic rhinosinusitis (CRS) is a heterogeneous chronic inflammatory disease generally divided based on the presence or absence of nasal…”
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Chronic airway inflammation provides a unique environment for B cell activation and antibody production by Feldman, S., Kasjanski, R., Poposki, J., Hernandez, D., Chen, J. N., Norton, J. E., Suh, L., Carter, R. G., Stevens, W. W., Peters, A. T., Kern, R. C., Conley, D. B., Tan, B. K., Shintani‐Smith, S., Welch, K. C., Grammer, L. C., Harris, K. E., Kato, A., Schleimer, R. P., Hulse, K. E.

“…Summary Background B cells play many roles in health and disease. However, little is known about the mechanisms that drive B cell responses in the airways,…”
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Reduced expression of antimicrobial PLUNC proteins in nasal polyp tissues of patients with chronic rhinosinusitis by Seshadri, S., Lin, D. C., Rosati, M., Carter, R. G., Norton, J. E., Suh, L., Kato, A., Chandra, R. K., Harris, K. E., W. Chu, H., Peters, A. T., Tan, B. K., Conley, D. B., Grammer, L. C., Kern, R. C., Schleimer, R. P.

“…Background Chronic rhinosinusitis (CRS) is a disease characterized by inflammation of the nasal mucosa and paranasal sinuses. This inflammation may result in…”
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Pathology of the Olfactory Mucosa: Implications for the Treatment of Olfactory Dysfunction by Kern, R C, Conley, D B, Haines III, G K, Robinson, A M

“…Objective: The pathology of the olfactory mucosa is poorly understood; however, most cases of hyposmia and anosmia appear to be associated with a decline in…”
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Pathology of the Olfactory Epithelium: Smoking and Ethanol Exposure by Vent, J, Robinson, A M., Gentry-Nielsen, M J., Conley, D B., Hallworth, R, Leopold, D A., Kern, R C.

“…Objective: To investigate the effects of tobacco smoke on the olfactory epithelium. Cigarette smoking has been associated with hyposmia; however, the…”
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Apoptosis in the Aging Olfactory Epithelium by Robinson, Alan M., Conley, D. B., Shinners, M. J., Kern, Robert C.

“…Objectives Olfactory receptor neurons undergo apoptosis at a baseline rate, probably secondary to environmental damage even in the absence of gross disease…”
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Treatment of Olfactory Dysfunction, II: Studies With Minocycline by Kern, R C., Conley, D B., Haines III, G K., Robinson, A M.

“…Objectives/Hypothesis: The treatment of anosmia has changed minimally since the early 1970s, despite dramatic advances in the understanding of the molecular…”
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Elevated presence of myeloid dendritic cells in nasal polyps of patients with chronic rhinosinusitis by Poposki, J. A., Peterson, S., Welch, K., Schleimer, R. P., Hulse, K. E., Peters, A. T., Norton, J., Suh, L. A., Carter, R., Harris, K. E., Grammer, L. C., Tan, B. K., Chandra, R. K., Conley, D. B., Kern, R. C., Kato, A.

“…Summary Background Although chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by Th2 inflammation, the mechanism underlying the onset and…”
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Olfactory neurons in bax knockout mice are protected from bulbectomy-induced apoptosis by Robinson, Alan M, Conley, David B, Kern, Robert C

“…Surgical ablation of the olfactory bulb (bulbectomy) triggers a massive wave of apoptosis in mature olfactory sensory neurons within the olfactory epithelium…”
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Management of sinusitis: current perspectives by Kern, R C, Conley, D B

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Short‐chain fatty acids induce tissue plasminogen activator in airway epithelial cells via GPR 41&43 by Imoto, Y., Kato, A., Takabayashi, T., Sakashita, M., Norton, J. E., Suh, L. A., Carter, R. G., Weibman, A. R., Hulse, K. E., Stevens, W., Harris, K. E., Peters, A. T., Grammer, L. C., Tan, B. K., Welch, K., Conley, D. B., Kern, R. C., Fujieda, S., Schleimer, R. P.

“…Summary Background Chronic rhinosinusitis ( CRS ) is a heterogeneous chronic inflammatory disease generally divided based on the presence or absence of nasal…”
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Efficacy of endoscopic sinus surgery in the management of patients with asthma and chronic sinusitis by Palmer, J N, Conley, D B, Dong, R G, Ditto, A M, Yarnold, P R, Kern, R C

“…An association between chronic sinusitis and asthma has been noted for many years, although the precise nature of the relationship is poorly understood…”
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Outcome analysis of endoscopic sinus surgery in patients with nasal polyps and asthma by Batra, Pete S., Kern, Robert C., Tripathi, Anju, Conley, David B., Ditto, A. M., Haines III, G. K., Yarnold, Paul R., Grammar, Leslie

“…Objective: To investigate the efficacy of endoscopic sinus surgery (ESS) in the management of chronic sinusitis and asthma in patients with nasal polyps and…”
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Superantigens and Chronic Rhinosinusitis: Detection of Staphylococcal Exotoxins in Nasal Polyps by Seiberling, Kristin A., Conley, David B., Tripathi, Anju, Grammer, Leslie C., Shuh, Lydia, Haines III, G Kenneth, Schleimer, Robert, Kern, Robert C.

“…Objective/Hypothesis: The role of infectious agents in the etiology of chronic rhinosinusitis with nasal polyposis (CRSwNP) remains unclear. Recent studies…”
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Medicolegal Analysis of Injury During Endoscopic Sinus Surgery by Lynn-Macrae, Alastair G., Lynn-Macrae, Rebecca A., Emani, Janaki, Kern, Robert C., Conley, David B.

“…Objectives: To survey the causes, characteristics, and outcomes of malpractice litigation resulting from injuries sustained during endoscopic sinus surgery…”
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Immunoglobulin E to Staphylococcal and Streptococcal Toxins in Patients with Chronic Sinusitis/Nasal Polyposis by Tripathi, Anju, Conley, David B., Grammer, Leslie C., Ditto, Anne M., Lowery, Margaret M., Seiberling, Kristen A., Yarnold, Paul A., Zeifer, Barbara, Kern, Robert C.

“…Background: The role of infectious agents and their contribution to the inflammation in chronic sinusitis/nasal polyposis (CS/NP) is not clear. Staphylococcal…”
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Aging and olfactory and taste function by Seiberling, Kristin A, Conley, David B

“…This article focuses on the change in olfaction and taste with aging. It discusses histopathology with an emphasis on age-related changes, causes of…”
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Heterogeneous inflammatory patterns in chronic rhinosinusitis without nasal polyps in Chicago, Illinois by Tan, Bruce K., MD, MS, Klingler, Aiko I., PhD, Poposki, Julie A., MS, Stevens, Whitney W., MD, PhD, Peters, Anju T., MD, Suh, Lydia A., BS, Norton, James, MS, Carter, Roderick G., BS, Hulse, Kathryn E., PhD, Harris, Kathleen E., BS, Grammer, Leslie C., MD, Schleimer, Robert P., PhD, Welch, Kevin C., MD, Smith, Stephanie S., MD, Conley, David B., MD, Kern, Robert C., MD, Kato, Atsushi, PhD

“…Because we found significant differences in the levels of CLC and IL-17A between control and CRSsNP in ET and not in IT or UT (Fig 1; see Fig E2 in this…”
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Characterization of Specific Antibody Deficiency in Adults with Medically Refractory Chronic Rhinosinusitis by Carr, T.F, Koterba, A.P, Chandra, R, Grammer, L.C, Conley, D.B, Harris, K.E, Kern, R, Schleimer, R.P, Tripathi-Peters, A

“…Each patient's record was reviewed for serum quantitative immunoglobulins and anti-pneumococcal antibody titers measured at baseline and 6 weeks…”
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Age-related Differences in the Pathogenesis of Chronic Rhinosinusitis by Hong, S.J, Han, B, Suh, L, Conley, D.B, Chandra, R, Kern, R.C, Grammer, L.C, Schleimer, R.P, Cho, S.H

“…Patients with CRS were recruited from the allergy and otolaryngology clinics at the Northwestern University Feinberg School of Medicine, and the clinical and…”
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