Search Results - "Conkling, P R"

Antitumor activity of ipatasertib combined with chemotherapy: results from a phase Ib study in solid tumors by Isakoff, S.J., Tabernero, J., Molife, L.R., Soria, J.-C., Cervantes, A., Vogelzang, N.J., Patel, M.R., Hussain, M., Baron, A., Argilés, G., Conkling, P.R., Sampath, D., Maslyar, D., Patel, P., Chan, W., Gendreau, S., Musib, L., Xu, N., Ma, H., Lin, K., Bendell, J.

“…This phase Ib study evaluated the safety, tolerability, pharmacokinetics, and preliminary efficacy of the oral AKT inhibitor ipatasertib and chemotherapy or…”
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Tumor Necrosis Factor Induces Tissue Factor-Like Activity in Human Leukemia Cell Line U937 and Peripheral Blood Monocytes by Conkling, Paul R., Greenberg, Charles S., Weinberg, J.Brice

“…The induction of procoagulant activity (PCA) by human recombinant tumor necrosis factor (rTNF) was studied in human monoblastic leukemia cell line U937 and…”
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Sphingosine inhibits monocyte tissue factor-initiated coagulation by altering factor VII binding by Conkling, P R, Patton, K L, Hannun, Y A, Greenberg, C S, Weinberg, J B

“…Tissue factor is a lipoprotein, expressed on the surface of cells, which binds coagulation Factor VII or VIIa, leading to activation of Factors X and IX with…”
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Tumor necrosis factor induces tissue factor-like activity in human leukemia cell line U937 and peripheral blood monocytes by Conkling, PR, Greenberg, CS, Weinberg, JB

“…The induction of procoagulant activity (PCA) by human recombinant tumor necrosis factor (rTNF) was studied in human monoblastic leukemia cell line U937 and…”
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Identification of Normal Human Peripheral Blood Monocytes and Liver as Sites of Synthesis of Coagulation Factor XIII a-Chain by Weisberg, Laurie J., Shiu, Donny T., Conkling, Paul R., Shuman, Marc A.

“…Factor XIII is the fibrin-stabilizing factor that covalently cross-links fibrin monomers to form a highly organized, stable fibrin clot. The plasma form of…”
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Brown blood: understanding methemoglobinemia by Conkling, P R

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Clinical trials with human tumor necrosis factor; in vivo and in vitro effects on human mononuclear phagocyte function by CONKLING, P. R, CHUA, C. C, NADLER, P, GREENBERG, C. S, DOTY, E, MISUKONIS, M. A, HANEY, A. F, BAST, R. C. JR, WEINBERG, J. B

“…The purpose of this investigation was to understand the biological effects of recombinant human tumor necrosis factor used as therapy for cancer. We studied…”
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Clinical activity, safety and predictive biomarkers results from a phase Ia atezolizumab (atezo) trial in extensive-stage small cell lung cancer (ES-SCLC) by Sequist, L.V., Chiang, A., Gilbert, J., Gordon, M., Conkling, P.R., Thompson, D., Marcoux, J.P., Antonia, S.J., Liu, B., Shames, D.S., Lopez-Chavez, A., O'Hear, C., Fasso, M., Gettinger, S.

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Human mononuclear phagocyte transglutaminase activity cross-links fibrin by Conkling, P R, Achyuthan, K E, Greenberg, C S, Newcomb, T F, Weinberg, J B

“…The physiologic function of the monocyte transglutaminases is not known. In this study, we detected Factor XIII A-subunit antigen and "tissue" transglutaminase…”
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A phase 1b study of abemaciclib, an inhibitor of CDK4 and CDK6, in combination with endocrine and HER2-targeted therapies for patients with metastatic breast cancer by Beeram, M., Tolaney, S.M., Beck, J.T., Dickler, M.N., Conlin, A.K., Dees, C., Helsten, T.L., Conkling, P.R., Edenfield, W.J., Richards, D.A., Kambhampati, S.R.P., Costigan, T.M., Chan, E., Pant, S., Kalinsky, K., Burris, H.A., Becerra, C.H., Rexer, B.N., Puhalla, S.L., Goetz, M.P.

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A randomized phase II trial of amrubicin (AMR) vs. topotecan as second-line treatment in extensive-disease small-cell lung cancer (SCLC) sensitive to platinum-based first-line chemotherapy by Jotte, R. M., Conkling, P. R., Reynolds, C., Allen, A. R., Oliver, J. W.

“…Abstract only…”
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Identification of normal human peripheral blood monocytes and liver as sites of synthesis of coagulation factor XIII a-chain by Weisberg, LJ, Shiu, DT, Conkling, PR, Shuman, MA

“…Factor XIII is the fibrin-stabilizing factor that covalently cross- links fibrin monomers to form a highly organized, stable fibrin clot. The plasma form of…”
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Novel organic arsenic molecule darinaparsin: Development of IV and oral forms by Lossos, I., Craig, M. D., Tallman, M. S., Boccia, R. V., Conkling, P. R., Becerra, C., Komarnitsky, P. B., Hamilton, B. L., Lewis, J., Miller, W. H.

“…Abstract only 8501 Background: Darinaparsin (ZIO-101) is a novel organic arsenical active against diverse cancers in vitro, and in vivo. Darinaparsin i.v…”
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A phase I study of imexon inj plus gemcitabine as first-line therapy for advanced pancreatic cancer with preclinical mechanistic study of dose limiting toxicity by Cohen, S. J., Zalupski, M. M., Modiano, M. R., Conkling, P. R., Patt, Y. Z., Davis, P., Dorr, R. T., Boytim, M. L., Hersh, E. M.

“…Abstract only…”
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Results of a phase II study of pemetrexed as first-line chemotherapy for advanced or metastatic breast cancer by Robert, N. J., Conkling, P. R., Kuefler, P. R., McIntyre, K. J., Zhan, F., Asmar, L., Wang, Y., Shonukan, O. O., O'Shaughnessy, J.

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Abstract P4-13-25: Abemaciclib, an inhibitor of CDK4 and CDK6, combined with endocrine and HER2-targeted therapies for women with metastatic breast cancer by Goetz, MP, Beeram, M, Beck, T, Conlin, AK, Dees, EC, Dickler, MN, Helsten, TL, Conkling, PR, Edenfield, WJ, Richards, DA, Turner, PK, Cai, N, Chan, EM, Pant, S, Becerra, CH, Kalinsky, K, Puhalla, SL, Rexer, BN, Burris, HA, Tolaney, SM

“…Background: Abemaciclib, a small molecule inhibitor of CDK4 and CDK6, induces G1 cell cycle arrest in Rb-proficient human cancers.1 The clinical safety profile…”
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Activation of Monocyte and Granulocyte Antibody-Dependent Cytotoxicity by Phorbol Myristate Acetate by Klassen, D K, Conkling, P R, Sagone, Jr, A L

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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