Search Results - "Conklin, Dawn R"

Sorrel Extract Reduces Oxidant Production in Airway Epithelial Cells Exposed to Swine Barn Dust Extract In Vitro by Williams, Leonard, Khatiwada, Janak R., Conklin, Dawn R., Kloc, Lauren L., Waterman, Jenora T., Ranabhat, Rohit S., McClendon, Chakia J., Gerald, Carresse L., Barton, Ke’Yona T.

“…Exposure to hog barn organic dust contributes to occupational lung diseases, which are mediated by inflammatory and oxidative stress pathways. Isoprostanes—a…”
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Preoperative Inhibition of Cyclooxygenase-1 in the Spinal Cord Reduces Postoperative Pain by Zhu, Xiaoying, Conklin, Dawn R., Eisenach, James C.

“…Intrathecal administration of cyclooxygenase (COX)-1, but not COX-2, specific inhibitors given on postoperative day 1 has analgesic effects in an incisional…”
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Intrathecal morphine reduces allodynia after peripheral nerve injury in rats via activation of a spinal A1 adenosine receptor by YONG ZHANG, CONKLIN, Dawn R, XINHUI LI, EISENACH, James C

“…The degree to which intrathecally administered morphine can alleviate hypersensitivity in animals after peripheral nerve injury is controversial, and the…”
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Assessment of Behavior during Labor in Rats and Effect of Intrathecal Morphine by CHUANYAO TONG, CONKLIN, Dawn R, BAOGANG LIU, RIRIE, Douglas G, EISENACH, James C

“…Efficacy of analgesics varies with the type of pain. Little is known in this regard concerning labor pain, given the ethical barriers to study in humans and…”
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5-Alk(en)ylresorcinols as the major active components in wheat bran inhibit human colon cancer cell growth by Zhu, Yingdong, Conklin, Dawn R., Chen, Huadong, Wang, Liyan, Sang, Shengmin

“…We and others have found that wheat bran oil is the active constituent in wheat bran for colon cancer prevention. However, the active components in wheat bran…”
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Methacholine induced airway contraction in porcine precision cut lung slices from indoor and outdoor reared pigs by Barton, Ke'Yona T, Conklin, Dawn R, Ranabhat, Rohit S, Harper, Marquis, Holmes-Cobb, La'Neesa M, Martinez Soto, Margarita H, Waterman, Jenora T

“…Repetitive exposure to bioaerosols in swine production facilities (SPF) promotes respiratory dysfunction in workers and animals. An adequate understanding of…”
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Induction of astrocyte metallothioneins (MTs) by zinc confers resistance against the acute cytotoxic effects of methylmercury on cell swelling, Na + uptake, and K + release by Aschner, Michael, Conklin, Dawn R, Yao, Chang Ping, Allen, Jeffrey W, Tan, Kim H

“…Metallothionein (MT) proteins play an important role in the detoxification of heavy metals. Since methylmercury (MeHg) preferentially accumulates in…”
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Intrathecal morphine and ketorolac analgesia after surgery: comparison of spontaneous and elicited responses in rats by Martin, Thomas J., Zhang, Yong, Buechler, Nancy, Conklin, Dawn R., Eisenach, James C.

“…Pain after surgery results in significant morbidity, and systemic opioids often fail to provide adequate analgesia without marked sedation and respiratory…”
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EXPOSURE TO SWINE HOUSING DUST MODULATES MACROPHAGE MORPHOLOGY AND FUNCTION by Pender, Ruth J, Minor, Radiah C, Hurley, Steven L, Conklin, Dawn R, Waterman, Jenora T

“…Swine Confinement Facility (SCF) dust consists of a complex mixture of feed grain particles, bacterial components, organic particulates and gases. When these…”
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Intrathecal ketorolac enhances antinociception from clonidine by CONKLIN, Dawn R, EISENACH, James C

“…Although both alpha2-adrenergic agonists and cyclooxygenase inhibitors produce analgesia, their exact sites of action and interaction remain unclear. A…”
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Methylmercury-induced astrocytic swelling is associated with activation of the Na +/H + antiporter, and is fully reversed by amiloride by Aschner, Michael, Vitarella, Domenico, Allen, Jeffrey W, Conklin, Dawn R, Cowan, Kelley S

“…Astrocytes are a known `sink' for brain methylmercury (MeHg) deposition. Yet, the significance of the preferential accumulation of MeHg within these cells is…”
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Induction of metallothionein-I (MT-I) mRNA in primary astrocyte cultures is mediated by hypotonicity and not ethanol (EtOH) per se by Aschner, Michael, Conklin, Dawn R, Aschner, Judy L

“…Metallothionein (MT) mRNA was determined in rat astrocyte cultures in response to ethanol (EtOH). MT-I mRNA was significantly increased after 6 h exposure to…”
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Intrathecal Ketorolac Enhances Antinociception from Clonidine by Conklin, Dawn R., Eisenach, James C.

“…Although both α2-adrenergic agonists and cyclooxygenase inhibitors produce analgesia, their exact sites of action and interaction remain unclear. A previous…”
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Antihypersensitivity Effect of Intrathecal Clonidine in a Rat Model of Postoperative Pain: Both a2A and a2NON A Adrenoceptors Participate: 2002[A-862 by Duflo, Frederic, Conklin, Dawn R., Eisenach, James C.

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Transfection and overexpression of metallothionein-I in neonatal rat primary astrocyte cultures and in astrocytoma cells increases their resistance to methylmercury-induced cytotoxicity by Yao, Chang Ping, Allen, Jeffrey W., Conklin, Dawn R., Aschner, Michael

“…Metallothionein-I (MT-I) was expressed in neonatal rat primary astrocyte cultures and an astrocytoma cell line by pGFAP-MT-I plasmid transfection under the…”
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Metallothionein induction protects swollen rat primary astrocyte cultures from methylmercury-induced inhibition of regulatory volume decrease by Vitarella, Domenico, Conklin, Dawn R., Kimelberg, Harold K., Aschner, Michael

“…Metallothionein (MT) proteins have been postulated to play a role in the detoxification of heavy metals. Since methylmercury (MeHg) preferentially accumulates…”
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Methylmercury-induced inhibition of regulatory volume decrease in astrocytes: characterization of osmoregulator efflux and its reversal by amiloride by Aschner, Michael, Vitarella, Domenico, Allen, Jeffrey W., Conklin, Dawn R., Cowan, Kelly S.

“…Swelling of neonatal rat primary astrocyte cultures by hypotonic media leads to regulatory volume decrease (RVD) and the resumption of resting cell volume. RVD…”
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Dimethyl sulfoxide, but not acidosis-induced metallothionein mRNA expression in neonatal rat primary astrocyte cultures is inhibited by the bioflavonoid, quercetin by Conklin, Dawn R., Tan, Kim H., Aschner, Michael

“…Metallothionein (MT) mRNA levels were analyzed following exposure of neonatal rat primary astrocyte cultures to physiologic pH (7.4), acidosis (pH 6.5 and…”
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