Search Results - "Congia, Mattia"
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Failure to achieve lupus low disease activity state (LLDAS) six months after diagnosis is associated with early damage accrual in Caucasian patients with systemic lupus erythematosus
Published in Arthritis research & therapy (10-11-2017)“…The aim was to assess the attainability and outcome of the lupus low disease activity state (LLDAS) in the early stages of systemic lupus erythematosus (SLE)…”
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Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial
Published in Nature medicine (01-06-2022)“…Patients with rheumatoid arthritis (RA) receive highly targeted biologic therapies without previous knowledge of target expression levels in the diseased…”
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Long-term glucocorticoid treatment and high relapse rate remain unresolved issues in the real-life management of polymyalgia rheumatica: a systematic literature review and meta-analysis
Published in Clinical rheumatology (01-01-2022)“…A systematic review and meta-analysis were conducted, according to the PRISMA methodology, to summarize current evidence on the prevalence and predictors of…”
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Molecular profiling of clinical remission in psoriatic arthritis reveals dysregulation of FOS and CCDC50 genes: a gene expression study
Published in Frontiers in immunology (27-10-2023)“…In psoriatic arthritis (PsA), the primary goal of treatment is clinical remission. This study aimed to characterize the molecular profile underlying the…”
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5
ERAP1 and ERAP2 Haplotypes Influence Suboptimal HLA-B27:05-Restricted Anti-Viral CD8+ T Cell Responses Cross-Reactive to Self-Epitopes
Published in International journal of molecular sciences (01-09-2023)“…The human leukocyte antigen (HLA)-B*27 family of alleles is strongly associated with ankylosing spondylitis (AS), a chronic inflammatory disorder affecting the…”
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Brain-reactive autoantibodies in neuropsychiatric systemic lupus erythematosus
Published in Frontiers in immunology (13-06-2023)“…The pathogenesis of neuropsychiatric systemic lupus erythematosus (NPSLE) is widely unknown, and the role of autoantibodies is still undetermined. To identify…”
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Targeted Therapies in Axial Psoriatic Arthritis
Published in Frontiers in genetics (28-06-2021)“…Specific and high-quality evidence on the efficacy of the current targeted therapies for axial disease in psoriatic arthritis (axPsA) is still scarce. Indeed,…”
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Effect of anti-P ribosomal and anti-NR2 antibodies on depression and cognitive processes in SLE: an integrated clinical and functional MRI study
Published in Lupus science & medicine (01-11-2023)“…ObjectivesTo explore the effects of anti-ribosomal P protein (anti-P) and anti-N-methyl-D-aspartic acid receptor subunit 2 (anti-NR2) autoantibodies on…”
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Predictors of musculoskeletal flares and Jaccoud′s arthropathy in patients with systemic lupus erythematosus: A 5-year prospective study
Published in Seminars in arthritis and rheumatism (01-10-2016)“…Abstract Objective To investigate the prognostic value of US in predicting musculoskeletal flares and Jaccoud′s arthropathy (JA) in Systemic Lupus…”
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Retention rate of biologic and targeted synthetic anti-rheumatic drugs in elderly rheumatoid arthritis patients: data from GISEA registry
Published in Frontiers in medicine (11-03-2024)“…An increased number of elderly individuals affected by rheumatoid arthritis (RA) has been reported, including both patients with RA onset in advanced age and…”
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Patterns of Anti-Inflammatory and Immunomodulating Drug Usage and Microvascular Endothelial Function in Rheumatoid Arthritis
Published in Frontiers in cardiovascular medicine (19-07-2021)“…Objectives: Specific anti-inflammatory and/or immunomodulating drugs (AIDs) can influence endothelial function which is often impaired in patients with…”
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Telemedicine in rheumatology: high specificity and sensitivity of follow-up virtual video consultations during COVID-19 pandemic
Published in Rheumatology (Oxford, England) (05-05-2022)“…Abstract Objective To evaluate the reliability of virtual video-assisted visits, added to the tight-control strategy for inflammatory rheumatic diseases…”
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Psychometric properties of patient global assessment in Psoriatic Arthritis: a systematic literature review
Published in Journal of rheumatology (15-02-2024)“…Patient Global Assessment (PtGA) is a patient-reported outcome (PRO) that reflects patients' judgment of health/disease activity (DA). The objective of this…”
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Treatment Target in Newly Diagnosed Systemic Lupus Erythematosus: The Association of Lupus Low Disease Activity State and Remission With Lower Accrual of Early Damage
Published in Arthritis care & research (2010) (01-12-2020)“…Objective To compare the effect of achievement and maintenance of Lupus Low Disease Activity State (LLDAS) and clinical remission (CR) in preventing early…”
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Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial
Published in The Lancet (British edition) (23-01-2021)“…Although targeted biological treatments have transformed the outlook for patients with rheumatoid arthritis, 40% of patients show poor clinical response, which…”
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Ultrasonographic assessment of bone erosions in the different subtypes of systemic lupus erythematosus arthritis: comparison with computed tomography
Published in Arthritis research & therapy (04-10-2016)“…The aim was to determine the accuracy of high-resolution ultrasonography (US) for detecting erosion in the metacarpophalangeal (MCP) and wrist joints of…”
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Treatment of psoriasis with different classes of biologics reduces the likelihood of peripheral and axial psoriatic arthritis development
Published in Rheumatology (Oxford, England) (23-05-2024)“…To assess the potential role of biological treatment for psoriasis (PsO) in reducing the likelihood of psoriatic arthritis (PsA), through a detailed analysis…”
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Imbalanced MMP-3 and MMP-12 serum levels in systemic lupus erythematosus patients with Jaccoud’s arthropathy and a distinctive MRI pattern
Published in Rheumatology (Oxford, England) (01-09-2021)“…Abstract Objective Metalloproteinase (MMP)-3 and MMP-12 are proteolytic enzymes especially implicated in joint inflammation. This study aims to evaluate their…”
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Biologics and Targeted Synthetic Drugs Can Induce Immune-Mediated Glomerular Disorders in Patients with Rheumatic Diseases: An Updated Systematic Literature Review
Published in BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy (01-03-2021)“…Objective Our objective was to update the understanding of the development of paradoxical immune-mediated glomerular disorders (IGDs) in patients with…”
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Current smoking predicts inadequate response to methotrexate monotherapy in rheumatoid arthritis patients naïve to DMARDs: Results from a retrospective cohort study
Published in Medicine (Baltimore) (30-04-2021)“…Identifying predictors of inadequate response to methotrexate (MTX) in rheumatoid arthritis (RA) is key to move from a "trial and error" to a "personalized…”
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