Search Results - "Congdon, Thomas R."

The atomistic details of the ice recrystallisation inhibition activity of PVA by Bachtiger, Fabienne, Congdon, Thomas R., Stubbs, Christopher, Gibson, Matthew I., Sosso, Gabriele C.

“…Understanding the ice recrystallisation inhibition (IRI) activity of antifreeze biomimetics is crucial to the development of the next generation of…”
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The SARS-COV‑2 Spike Protein Binds Sialic Acids and Enables Rapid Detection in a Lateral Flow Point of Care Diagnostic Device by Baker, Alexander N, Richards, Sarah-Jane, Guy, Collette S, Congdon, Thomas R, Hasan, Muhammad, Zwetsloot, Alexander J, Gallo, Angelo, Lewandowski, Józef R, Stansfeld, Phillip J, Straube, Anne, Walker, Marc, Chessa, Simona, Pergolizzi, Giulia, Dedola, Simone, Field, Robert A, Gibson, Matthew I

“…There is an urgent need to understand the behavior of the novel coronavirus (SARS-COV-2), which is the causative agent of COVID-19, and to develop…”
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Polymer Self-Assembly Induced Enhancement of Ice Recrystallization Inhibition by Georgiou, Panagiotis G, Marton, Huba L, Baker, Alexander N, Congdon, Thomas R, Whale, Thomas F, Gibson, Matthew I

“…Ice binding proteins modulate ice nucleation/growth and have huge (bio)­technological potential. There are few synthetic materials that reproduce their…”
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Influence of Block Copolymerization on the Antifreeze Protein Mimetic Ice Recrystallization Inhibition Activity of Poly(vinyl alcohol) by Congdon, Thomas R, Notman, Rebecca, Gibson, Matthew I

“…Antifreeze (glyco) proteins are produced by many cold-acclimatized species to enable them to survive subzero temperatures. These proteins have multiple…”
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Red Blood Cell Cryopreservation with Minimal Post-Thaw Lysis Enabled by a Synergistic Combination of a Cryoprotecting Polyampholyte with DMSO/Trehalose by Murray, Alex, Congdon, Thomas R, Tomás, Ruben M. F, Kilbride, Peter, Gibson, Matthew I

“…From trauma wards to chemotherapy, red blood cells are essential in modern medicine. Current methods to bank red blood cells typically use glycerol (40 wt %)…”
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Assay-ready Cryopreserved Cell Monolayers Enabled by Macromolecular Cryoprotectants by Tomás, Ruben M. F., Bissoyi, Akalabya, Congdon, Thomas R., Gibson, Matthew I.

“…Cell monolayers underpin the discovery and screening of new drugs and allow for fundamental studies of cell biology and disease. However, current…”
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Photo-polymerisation and study of the ice recrystallisation inhibition of hydrophobically modified poly(vinyl pyrrolidone) co-polymers by Stubbs, Christopher, Congdon, Thomas R, Gibson, Matthew I.

“…[Display omitted] •Vinyl pyrrolidone was polymerized by photochemical RAFT in absence of external radical source.•Copolymers for post-polymerization…”
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Synthesis of star-branched poly(vinyl alcohol) and ice recrystallization inhibition activity by Congdon, Thomas R., Notman, Rebecca, Gibson, Matthew I.

“…[Display omitted] •The design and synthesis of a simple and efficient trifunctional MADIX agent is reported.•Excellent VAc control was achieved and well…”
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Poly(vinyl alcohol) Molecular Bottlebrushes Nucleate Ice by Georgiou, Panagiotis G., Kinney, Nina L. H., Kontopoulou, Ioanna, Baker, Alexander N., Hindmarsh, Steven A., Bissoyi, Akalabya, Congdon, Thomas R., Whale, Thomas F., Gibson, Matthew I.

“…Ice binding proteins (IBP) have evolved to limit the growth of ice but also to promote ice formation by ice-nucleating proteins (INPs). IBPs, which modulate…”
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Evidence, Manipulation, and Termination of pH ‘Nanobuffering’ for Quantitative Homogenous Scavenging of Monoclonal Antibodies by Anees, Palapuravan, Zhao, Yi, Greschner, Andrea A, Congdon, Thomas R, de Haan, Hendrick W, Cottenye, Nicolas, Gauthier, Marc A

“…This study demonstrates that pH-responsive polymers have a very high buffering capacity in their immediate vicinity, a phenomenon termed “nanobuffering”. This…”
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End-Functionalized Poly(vinylpyrrolidone) for Ligand Display in Lateral Flow Device Test Lines by Baker, Alexander N, Congdon, Thomas R, Richards, Sarah-Jane, Georgiou, Panagiotis G, Walker, Marc, Dedola, Simone, Field, Robert A, Gibson, Matthew I

“…Lateral flow devices are rapid (and often low cost) point-of-care diagnosticsthe classic example being the home pregnancy test. A test line (the stationary…”
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Surface vs. core N/S/Se-heteroatom doping of carbon nanodots produces divergent yet consistent optical responses to reactive oxygen species by Geng, Xu, Congdon, Thomas R., Anees, Palapuravan, Greschner, Andrea A., Vetrone, Fiorenzo, Gauthier, Marc A.

“…Carbon nanodots (CNDs) have attracted substantial scientific curiosity because of their intriguing stimuli-responsive optical properties. However, one obstacle…”
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Ice recrystallisation inhibiting polymers prevent irreversible protein aggregation during solvent-free cryopreservation as additives and as covalent polymer-protein conjugates by Fayter, Alice E.R., Hasan, Muhammad, Congdon, Thomas R., Kontopoulou, Ioanna, Gibson, Matthew I.

“…[Display omitted] •Poly(vinyl alcohol) allows solvent-free protein cryopreservation.•Lactate dehydrogenase and green fluorescent protein were both successful…”
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Polyurea microcapsules from isocyanatoethyl methacrylate copolymers by Risangud, Nuttapol, Congdon, Thomas R., Keddie, Daniel J., Wilson, Paul, Kempe, Kristian, Haddleton, David M.

“…ABSTRACT The synthesis of two types of isocyanate side chain containing copolymers, poly(methyl methacrylate‐co‐isocyanatoethyl methacrylate) (P(MMA‐co‐IEM))…”
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Surface core N/S/Se-heteroatom doping of carbon nanodots produces divergent yet consistent optical responses to reactive oxygen species by Geng, Xu, Congdon, Thomas R, Anees, Palapuravan, Greschner, Andrea A, Vetrone, Fiorenzo, Gauthier, Marc A

“…Carbon nanodots (CNDs) have attracted substantial scientific curiosity because of their intriguing stimuli-responsive optical properties. However, one obstacle…”
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