Search Results - "Cone, Allaura"

Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model by Cone, Allaura S, Yuan, Xuegang, Sun, Li, Duke, Leanne C, Vreones, Michael P, Carrier, Allison N, Kenyon, Stephanie M, Carver, Spencer R, Benthem, Sarah D, Stimmell, Alina C, Moseley, Shawn C, Hike, David, Grant, Samuel C, Wilber, Aaron A, Olcese, James M, Meckes, Jr, David G

“…Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that affects more than 44 million people worldwide. Despite the high disease burden,…”
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Epstein-Barr Virus LMP1 Modulates the CD63 Interactome by Cheerathodi, Mujeeb, Nkosi, Dingani, Cone, Allaura S, York, Sara B, Meckes, Jr, David G

“…Tetraspanin CD63 is a cluster of cell surface proteins with four transmembrane domains; it is associated with tetraspanin-enriched microdomains and typically…”
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CD81 fusion alters SARS-CoV-2 Spike trafficking by Cone, Allaura S, Zhou, Yijun, McNamara, Ryan P, Eason, Anthony B, Arias, Gabriel F, Landis, Justin T, Shifflett, Kyle W, Chambers, Meredith G, Yuan, Runjie, Willcox, Smaranda, Griffith, Jack D, Dittmer, Dirk P

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic caused the biggest public health crises in recent history. Many expect future…”
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Zika Virus Hijacks Extracellular Vesicle Tetraspanin Pathways for Cell-to-Cell Transmission by York, Sara B, Sun, Li, Cone, Allaura S, Duke, Leanne C, Cheerathodi, Mujeeb R, Meckes, Jr, David G

“…Extracellular vesicles (EVs) are membrane-encapsulated structures released by cells which carry signaling factors, proteins, and microRNAs that mediate…”
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Alix and Syntenin-1 direct amyloid precursor protein trafficking into extracellular vesicles by Cone, Allaura S, Hurwitz, Stephanie N, Lee, Gloria S, Yuan, Xuegang, Zhou, Yi, Li, Yan, Meckes, Jr, David G

“…Endosomal trafficking and amyloidogenic cleavage of amyloid precursor protein (APP) is believed to play a role in the neurodegeneration observed in Alzheimer's…”
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Large‐scale heparin‐based bind‐and‐elute chromatography identifies two biologically distinct populations of extracellular vesicles by Zhou, Yijun, Yuan, Runjie, Cone, Allaura S., Shifflett, Kyle W., Arias, Gabriel F., Peng, Alice, Chambers, Meredith G., McNamara, Ryan P., Willcox, Smaranda, Landis, Justin T., Pan, Yue, Griffith, Jack, Dittmer, Dirk P.

“…ABSTRACT Purifying extracellular vesicles (EVs) has been challenging because EVs are heterogeneous in cargo yet share similar sizes and densities. Most surface…”
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Biogenesis of Extracellular Vesicles Produced from Human-Stem-Cell-Derived Cortical Spheroids Exposed to Iron Oxides by Marzano, Mark, Bou-Dargham, Mayassa J, Cone, Allaura S, York, Sara, Helsper, Shannon, Grant, Samuel C, Meckes, David G, Sang, Qing-Xiang Amy, Li, Yan

“…Stem-cell-derived extracellular vesicles (EVs) are promising tools for therapeutic delivery and imaging in the medical research fields. EVs that arise from…”
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Extracellular Vesicles in Epstein-Barr Virus Pathogenesis by Cone, Allaura S., York, Sara B., Meckes, David G.

“…Purpose of Review Epstein-Barr virus (EBV) is a known determinant for numerous malignancies and may contribute to autoimmune diseases. The underlining…”
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Coordination of Zika Virus Infection and Viroplasm Organization by Microtubules and Microtubule-Organizing Centers by Buchwalter, Rebecca A, Ogden, Sarah C, York, Sara B, Sun, Li, Zheng, Chunfeng, Hammack, Christy, Cheng, Yichen, Chen, Jieyan V, Cone, Allaura S, Meckes, Jr, David G, Tang, Hengli, Megraw, Timothy L

“…Zika virus (ZIKV) became a global health concern in 2016 due to its links to congenital microcephaly and other birth defects. Flaviviruses, including ZIKV,…”
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Zika Virus Infection Induces DNA Damage Response in Human Neural Progenitors That Enhances Viral Replication by Hammack, Christy, Ogden, Sarah C, Madden, Jr, Joseph C, Medina, Angelica, Xu, Chongchong, Phillips, Ernest, Son, Yuna, Cone, Allaura, Giovinazzi, Serena, Didier, Ruth A, Gilbert, David M, Song, Hongjun, Ming, Guoli, Wen, Zhexing, Brinton, Margo A, Gunjan, Akash, Tang, Hengli

“…Zika virus (ZIKV) infection attenuates the growth of human neural progenitor cells (hNPCs). As these hNPCs generate the cortical neurons during early brain…”
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Extracellular Vesicles in Disease Pathogenesis and as a Therapeutic Agent by Cone, Allaura Sherman

“…Extracellular vesicles (EVs) are a heterogeneous population of membrane-bound nanoparticles that are essential mediators of cell-to-cell communication. They…”
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Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model by Cone, Allaura S., Yuan, Xuegang, Sun, Li, Duke, Leanne C., Vreones, Michael P., Carrier, Allison N., Kenyon, Stephanie M., Carver, Spencer R., Benthem, Sarah D., Stimmell, Alina C., Moseley, Shawn C., Hike, David, Grant, Samuel C., Wilber, Aaron A., Olcese, James M., Meckes, David G.

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