Search Results - "Condra, C"

Cloning of the cDNA and expression of moubatin, an inhibitor of platelet aggregation by Keller, P.M, Waxman, L, Arnold, B.A, Schultz, L.D, Condra, C, Connolly, T.M

“…Moubatin, a new type of specific inhibitor of collagen-induced platelet aggregation, has been isolated from the soft tick Ornithodoros moubata (Waxman, L., and…”
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Species variability in platelet and other cellular responsiveness to thrombin receptor-derived peptides by Connolly, T M, Condra, C, Feng, D M, Cook, J J, Stranieri, M T, Reilly, C F, Nutt, R F, Gould, R J

“…The aggregation of platelets from a variety of animal species in response to thrombin receptor-derived activating peptides was evaluated. A series of…”
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An inhibitor of collagen-stimulated platelet activation from the salivary glands of the Haementeria officinalis leech. I. Identification, isolation, and characterization by CONNOLLY, T. M, JACOBS, J. W, CONDRA, C

“…A protein that blocks collagen-stimulated platelet aggregation has been identified and isolated from the soluble fraction of salivary glands from Haementeria…”
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Determination of total, saturated, unsaturated, and monounsaturated fats in cereal products by acid hydrolysis and capillary gas chromatography: collaborative study by Ngeh-Ngwainbi, J. (Kellogg Company, Battle Creek, MI.), Lin, J, Chandler, A

“…Fifteen laboratories participated in a collaborative study to determine total, saturated, unsaturated, and monounsaturated fats in cereal products by gas…”
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An inhibitor of collagen-stimulated platelet activation from the salivary glands of the Haementeria officinalis leech. II. Cloning of the cDNA and expression by KELLER, P. M, SCHULTZ, L. D, CONDRA, C, KARCZEWSKI, J, CONNOLLY, T. M

“…Salivary glands of the leech Haementeria officinalis contain a protein, leech antiplatelet protein (LAPP), that specifically blocks collagen-mediated platelet…”
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Isolation and structural characterization of a potent inhibitor of coagulation factor Xa from the leech Haementeria ghilianii by Condra, C, Nutt, E, Petroski, C J, Simpson, E, Friedman, P A, Jacobs, J W

“…The present work reports the discovery and characterization of an anticoagulant protein in the salivary gland of the giant bloodsucking leech, H. ghilianii,…”
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Clearance and early hydrolysis of atrial natriuretic factor in vivo: structural analysis of cleavage sites and design of an analogue that inhibits hormone cleavage by CONDRA, C. L, LEIDY, E. A, BUNTING, P, COLTON, C. D, NUTT, R. F, ROSENBLATT, M, JACOBS, J. W

“…This study examines the clearance and early hydrolysis of atrial natriuretic factor (ANF) in vivo. Radiolabeled ANF was cleared from the circulation of the rat…”
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Cloning and Expression of a Viral Phosphoprotein: Structure Suggests Vesicular Stomatitis Virus NS May Function by Mimicking an RNA Template by Hudson, Lynn D, Condra, Cindra, Lazzarini, Robert A

“…Laboratory of Molecular Genetics, IRP, NINCDS, Building 36, Room 4A01, 9000 Rockville Pike, Bethesda, Maryland 20892, U.S.A. The phosphoprotein (NS) gene from…”
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Psychiatric Patients in the Pediatric Emergency Department Undergoing Routine Urine Toxicology Screens for Medical Clearance: Results and Use by Fortu, Jesusa Milalaine T, Kim, In K, Cooper, Amy, Condra, Cole, Lorenz, Douglas J, Pierce, Mary Clyde

“…OBJECTIVE:We sought to determine the use and results of urine toxicology screens (UTS) in psychiatric patients undergoing a UTS test for medical clearance in a…”
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Resource partitioning among genotypes of Drosophila pseudoobscura by Taylor, C.E, Condra, C

“…Many models of selection in heterogeneous environments have now been studied. These differ widely in the predictions they make regarding the association…”
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In Vitro Transcription of Vesicular Stomatitis Virus: Initiation with GTP at a Specific Site Within the N Cistron by Schubert, M, Harmison, G G, Sprague, J, Condra, C S, Lazzarini, R A

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Discovery of a nonpeptidic small molecule antagonist of the human platelet thrombin receptor (PAR-1) by Nantermet, Philippe G, Barrow, James C, Lundell, George F, Pellicore, Janetta M, Rittle, Kenneth E, Young, MaryBeth, Freidinger, Roger M, Connolly, Thomas M, Condra, Cindra, Karczewski, Jerzy, Bednar, Rodney A, Gaul, Stanley L, Gould, Robert J, Prendergast, Kris, Selnick, Harold G

“…The synthesis and biological evaluation of a series of nonpeptidic small molecule antagonists of the human platelet thrombin receptor (PAR-1) are described…”
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An inhibitor of collagen-stimulated platelet activation from the salivary glands of the Haementeria officinalis leech. 1. Identification, isolation, and characterization by Connolly, T M, Jacobs, J W, Condra, C

“…A protein that blocks collagen-stimulated platelet aggregation has been identified and isolated from the soluble fraction of salivary glands from Haementeria…”
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Platelet aggregation monitored in a 96 well microplate reader is useful for evaluation of platelet agonists and antagonists by Bednar, Bohumil, Condra, Cindra, Gould, Robert J., Connolly, Thomas M.

“…Optimal conditions for a method to simultaneously measure aggregation in 96 samples using a microplate reader were developed. The temperature of the assay was…”
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An antibody against the exosite of the cloned thrombin receptor inhibits experimental arterial thrombosis in the African green monkey by COOK, J. J, SITKO, G. R, BEDNAR, B, CONDRA, C, MELLOTT, M. J, DONG-MEI FENG, NUTT, R. F, SHAFER, J. A, GOULD, R. J, CONNOLLY, T. M

“…Thrombin inhibitors have been shown to be efficacious in animal models of thrombosis and in initial human clinical trials. It is unknown if their efficacy is…”
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Discovery and initial structure–Activity relationships of trisubstituted ureas as thrombin receptor (PAR-1) antagonists by Barrow, James C, Nantermet, Philippe G, Selnick, Harold G, Glass, Kristen L, Ngo, Phung L, Young, Mary Beth, Pellicore, Janetta M, Breslin, Michael J, Hutchinson, John H, Freidinger, Roger M, Condra, Cindra, Karczewski, Jerzy, Bednar, Rodney A, Gaul, Stanley L, Stern, Andrew, Gould, Robert, Connolly, Thomas M

“…Thrombin is the most potent agonist of platelet activation, and its effects are predominantly mediated by platelet thrombin receptors. Therefore, antagonists…”
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Development of a Potent Thrombin Receptor Ligand by Feng, Dong-Mei, Veber, Daniel F, Connolly, Thomas M, Condra, Cindra, Tang, Mei-Jy, Nutt, Ruth F

“…The N-terminal thrombin receptor peptide H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OH (1) fully activates the thrombin receptor with an EC50 of…”
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An inhibitor of collagen-stimulated platelet activation from the salivary glands of the Haementeria officinalis leech. 2. Cloning of the cDNA and expression by Keller, P M, Schultz, L D, Condra, C, Karczewski, J, Connolly, T M

“…Salivary glands of the leech Haementeria officinalis contain a protein, leech antiplatelet protein (LAPP), that specifically blocks collagen-mediated platelet…”
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NR2B-Selective N-Methyl-d-aspartate Antagonists:  Synthesis and Evaluation of 5-Substituted Benzimidazoles by McCauley, John A., Theberge, Cory R., Romano, Joseph J., Billings, Susan B., Anderson, Kenneth D., Claremon, David A., Freidinger, Roger M., Bednar, Rodney A., Mosser, Scott D., Gaul, Stanley L., Connolly, Thomas M., Condra, Cindra L., Xia, Menghang, Cunningham, Michael E., Bednar, Bohumil, Stump, Gary L., Lynch, Joseph J., Macaulay, Alison, Wafford, Keith A., Koblan, Kenneth S., Liverton, Nigel J.

“…Two classes of 5-substituted benzimidazoles were identified as potent antagonists of the NR2B subtype of the N-methyl-d-aspartate (NMDA) receptor. Selected…”
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Gamma- and K-selection in Drosophila pseudoobscura by Taylor C.E, Condra C

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