Search Results - "Condello, Salvatore"

Lipid Desaturation Is a Metabolic Marker and Therapeutic Target of Ovarian Cancer Stem Cells by Li, Junjie, Condello, Salvatore, Thomes-Pepin, Jessica, Ma, Xiaoxiao, Xia, Yu, Hurley, Thomas D., Matei, Daniela, Cheng, Ji-Xin

“…Lack of sensitive single-cell analysis tools has limited the characterization of metabolic activity in cancer stem cells. By hyperspectral-stimulated Raman…”
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MutSignatures: an R package for extraction and analysis of cancer mutational signatures by Fantini, Damiano, Vidimar, Vania, Yu, Yanni, Condello, Salvatore, Meeks, Joshua J.

“…Cancer cells accumulate somatic mutations as result of DNA damage, inaccurate repair and other mechanisms. Different genetic instability processes result in…”
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Tissue Tranglutaminase Regulates Interactions between Ovarian Cancer Stem Cells and the Tumor Niche by Condello, Salvatore, Sima, Livia, Ivan, Cristina, Cardenas, Horacio, Schiltz, Gary, Mishra, Rama K, Matei, Daniela

“…Cancer progression and recurrence are linked to a rare population of cancer stem cells (CSC). Here, we hypothesized that interactions with the extracellular…”
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Tissue Transglutaminase Mediated Tumor-Stroma Interaction Promotes Pancreatic Cancer Progression by Lee, Jiyoon, Condello, Salvatore, Yakubov, Bakhtiyor, Emerson, Robert, Caperell-Grant, Andrea, Hitomi, Kiyotaka, Xie, Jingwu, Matei, Daniela

“…Aggressive pancreatic cancer is commonly associated with a dense desmoplastic stroma, which forms a protective niche for cancer cells. The objective of the…”
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The Outside-In Journey of Tissue Transglutaminase in Cancer by Sima, Livia Elena, Matei, Daniela, Condello, Salvatore

“…Tissue transglutaminase (TG2) is a member of the transglutaminase family that catalyzes Ca -dependent protein crosslinks and hydrolyzes guanosine…”
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Prevention of Cerebral Lesion in Asymptomatic Carotid and Vertebral Artery Stenosis in Urgent Cardiac Surgery by Condello, Ignazio, Condello, Salvatore

“…Near-infrared spectroscopy (NIRS) allows assessment of cerebral oxygen delivery and the demands ratio to the frontal cortex. Routine use of cerebral rSO2…”
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Integrin-linked kinase-frizzled 7 interaction maintains cancer stem cells to drive platinum resistance in ovarian cancer by Atwani, Rula, Nagare, Rohit Pravin, Rogers, Amber, Prasad, Mayuri, Lazar, Virginie, Sandusky, George, Tong, Yan, Pin, Fabrizio, Condello, Salvatore

“…Platinum-based chemotherapy regimens are a mainstay in the management of ovarian cancer (OC), but emergence of chemoresistance poses a significant clinical…”
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Correction: Integrin-linked kinase-frizzled 7 interaction maintains cancer stem cells to drive platinum resistance in ovarian cancer by Atwani, Rula, Nagare, Rohit Pravin, Rogers, Amber, Prasad, Mayuri, Lazar, Virginie, Sandusky, George, Tong, Yan, Pin, Fabrizio, Condello, Salvatore

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Interferon-γ signaling is associated with BRCA1 loss-of-function mutations in high grade serous ovarian cancer by Cardenas, Horacio, Jiang, Guanglong, Thomes Pepin, Jessica, Parker, J. Brandon, Condello, Salvatore, Nephew, Kenneth P., Nakshatri, Harikrishna, Chakravarti, Debabrata, Liu, Yunlong, Matei, Daniela

“…Loss-of-function mutations of the breast cancer type 1 susceptibility protein (BRCA1) are associated with breast (BC) and ovarian cancer (OC). To identify gene…”
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Protective Effects of Zonisamide Against Rotenone-Induced Neurotoxicity by Condello, Salvatore, Currò, Monica, Ferlazzo, Nadia, Costa, Gregorio, Visalli, Giuseppa, Caccamo, Daniela, Pisani, Laura Rosa, Costa, Cinzia, Calabresi, Paolo, Ientile, Riccardo, Pisani, Francesco

“…Zonisamide (ZNS), an antiepileptic drug having beneficial effects also against Parkinson’s disease symptoms, has proven to display an antioxidant effects in…”
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Fat Emboli Filtration in Infant Population for Excluding Their Role in Neurodevelopmental Outcomes by Condello, Ignazio, Condello, Salvatore

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NF-kappaB activation is associated with homocysteine-induced injury in Neuro2a cells by Ferlazzo, Nadia, Condello, Salvatore, Currò, Monica, Parisi, Giulia, Ientile, Riccardo, Caccamo, Daniela

“…Perinatal exposure to hyperhomocysteinemia might disturb neurogenesis during brain development and growth. Also, high levels of homocysteine trigger…”
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“The Research of the Angels’ Sex!” Postoperative Delirium and Cardiopulmonary Bypass Correlation by Condello, Ignazio, Condello, Salvatore

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Critical role of transglutaminase and other stress proteins during neurodegenerative processes by Caccamo, Daniela, Currò, Monica, Condello, Salvatore, Ferlazzo, Nadia, Ientile, Riccardo

“…Proteolytic stress, resulting from the intracellular accumulation of misfolded or aggregated proteins, which exceed the capacity of the ubiquitin-proteasome…”
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Homocysteine induces DNA damage and alterations in proliferative capacity of T-lymphocytes : a model for immunosenescence? by PICERNO, Isa, CHIRICO, Cristina, CONDELLO, Salvatore, VISALLI, Giuseppa, FERLAZZO, Nadia, GORGONE, Gaetano, CACCAMO, Daniela, IENTILE, Riccardo

“…Homocysteine (Hcy) appears to exert different effects on immune functions possibly contributing to age-related pathological states, including vascular…”
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Tissue transglutaminase activates integrin-linked kinase and β-catenin in ovarian cancer by Condello, Salvatore, Prasad, Mayuri, Atwani, Rula, Matei, Daniela

“…Ovarian cancer (OC) is the most lethal gynecological cancer. OC cells have high proliferative capacity, are invasive, resist apoptosis, and tumors often…”
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The relationship between the xenotransplantation limitations and Charles Darwin theory on human evolution by Condello, Ignazio, Condello, Salvatore

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Modulation of heat shock protein response in SH-SY5Y by mobile phone microwaves by Emanuele Calabrò;Salvatore Condello;Monica Currò;Nadia Ferlazzo;Daniela Caccamo;Salvatore Magazù;Riccardo Ientile

“…AIM: To investigate putative biological damage caused by GSM mobile phone frequencies by assessing electromagnetic fields during mobile phone working. METHODS:…”
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Tissue transglutaminase regulates β‐catenin signaling through a c‐Src‐dependent mechanism by Condello, Salvatore, Cao, Liyun, Matei, Daniela

“…Tissue transglutaminase (TG2) is a multifunctional enzyme involved in protein cross‐linking and cell adhesion to fibronectin (FN). In cancer, TG2 induces an…”
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Frizzled-7 Identifies Platinum-Tolerant Ovarian Cancer Cells Susceptible to Ferroptosis by Wang, Yinu, Zhao, Guangyuan, Condello, Salvatore, Huang, Hao, Cardenas, Horacio, Tanner, Edward J, Wei, JianJun, Ji, Yanrong, Li, Junjie, Tan, Yuying, Davuluri, Ramana V, Peter, Marcus E, Cheng, Ji-Xin, Matei, Daniela

“…Defining traits of platinum-tolerant cancer cells could expose new treatment vulnerabilities. Here, new markers associated with platinum-tolerant cells and…”
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