Search Results - "Conde, Sandro Jose"
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A comparative genotoxicity study of a supraphysiological dose of triiodothyronine (T₃) in obese rats subjected to either calorie-restricted diet or hyperthyroidism
Published in PloS one (28-02-2013)“…This study was designed to determine the genotoxicity of a supraphysiological dose of triiodothyronine (T3) in both obese and calorie-restricted obese animals…”
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Triiodothyronine increases mRNA and protein leptin levels in short time in 3T3-L1 adipocytes by PI3K pathway activation
Published in PloS one (18-09-2013)“…The present study aimed to examine the effects of thyroid hormone (TH), more precisely triiodothyronine (T3), on the modulation of leptin mRNA expression and…”
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Learning Material design for teaching Genetics while implementing Flipped Classroom
Published in Revista Ibero-Americana de Estudos em Educação (01-05-2018)“…This paper shows the process of research and design of learning materials for flipped classrooms, an active teaching method that intends to switch from the…”
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Estrogen-Responsive Genes Overlap with Triiodothyronine-Responsive Genes in a Breast Carcinoma Cell Line
Published in TheScientificWorld (01-01-2014)“…It has been well established that estrogen plays an important role in the progression and treatment of breast cancer. However, the role of triiodothyronine…”
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Experimental Hyperthyroidism Decreases Gene Expression and Serum Levels of Adipokines in Obesity
Published in TheScientificWorld (01-01-2012)“…Aims. To analyze the influence of hyperthyroidism on the gene expression and serum concentration of leptin, resistin, and adiponectin in obese animals. Main…”
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Triiodothyronine (T3) induces HIF1A and TGFA expression in MCF7 cells by activating PI3K
Published in Life sciences (1973) (01-06-2016)“…High expression levels of hypoxia inducing factor 1 alpha are related to mammary carcinogenesis. In previous studies, we demonstrated that expression of…”
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Triiodothyronine and breast cancer
Published in World journal of clinical oncology (10-08-2014)“…The thyroid hormones (THs), triiodothyronine (T3) and thyroxine (T4), are essential for survival; they are involved in the processes of development, growth,…”
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Human breast tumor slices as an alternative approach to cell lines to individualize research for each patient
Published in European journal of cancer prevention (01-07-2012)“…There are several breast cancer experimental models including cell lines, which are commonly used due to ease of handling and storage. However, the continued…”
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Reverse T 3 as a parameter of myocardial function impairment in heart failure
Published in International journal of cardiology (05-11-2010)“…Sick Euthyroid Syndrome (SES) has been defined as low T 3 levels in the presence of normal TSH concentrations. The purpose of this study was to assess the…”
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10
Upregulation of mRNA myocardium calcium handling in rats submitted to exercise and food restriction
Published in Arquivos brasileiros de cardiologia (01-07-2011)“…Chronic exercise and food restriction (FR) have directionally opposite changes in transcription of molecular structures of calcium handling and thyroid hormone…”
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The importance of hormone receptor analysis in osteosarcoma cells growth submitted to treatment with estrogen in association with thyroid hormone
Published in Cell biochemistry and function (01-01-2008)“…Bone tumor incidence in women peaks at age 50–60, coinciding with the menopause. That estrogen (E2) and triiodothyronine (T3) interact in bone metabolism has…”
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Thyroid Hormone Status Interferes with Estrogen Target Gene Expression in Breast Cancer Samples in Menopausal Women
Published in ISRN endocrinology (2014)“…We investigated thyroid hormone levels in menopausal BrC patients and verified the action of triiodothyronine on genes regulated by estrogen and by…”
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Modulation of Amphiregulin Gene Expression by Estrogen in Breast Cancer Cells
Published in The FASEB journal (01-04-2013)“…Abstract only This study aimed evaluate whether estrogen modulates amphiregulin (AREG) gene expression in breast tumor cells. For this, MCF‐7 cells were…”
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Severe food restriction induces myocardial dysfunction related to SERCA2 activity
Published in Canadian journal of physiology and pharmacology (01-09-2009)“…Previous studies have shown that food restriction promotes myocardial dysfunction in rats. However, the molecular mechanisms that are responsible are unclear…”
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Triiodothyronine indirectly increases amphiregulin gene expression levels via estrogen receptor activation
Published in The FASEB journal (01-04-2013)“…Abstract only The objective of this study was to determine whether triiodothyronine hormone (T 3 ) exerts direct or indirect modulation in amphiregulin (AREG)…”
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Triiodothyronine increases adiponectin mRNA by indirect action in adipocytes cell culture, 3T3‐L1
Published in The FASEB journal (01-04-2013)“…Abstract only The aim of this study was to examine the effects of thyroid hormone (TH), triiodothyronine (T 3 ), in the modulation of adiponectin mRNA…”
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Perfil dos hormônios da tireoide em pacientes com câncer de mama em estado de menopausa
Published in Arquivos brasileiros de endocrinologia e metabologia (01-06-2012)“…OBJETIVO: Verificar o perfil dos hormônios tireóideos (HTs) em pacientes pós-menopausa portadoras de carcinoma de mama (CaM). SUJEITOS E MÉTODOS: Participaram…”
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Exercício e restrição alimentar aumentam o RNAm de proteínas do trânsito de Ca2+ miocárdico em ratos
Published in Arquivos brasileiros de cardiologia (01-07-2011)“…FUNDAMENTO: Treinamento físico (TF) aumenta a sensibilidade dos hormônios tireoidianos (HT) e a expressão gênica de estruturas moleculares envolvidas no…”
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Thyroid hormone status interferes with estrogen target gene expression in breast cancer samples of menopausal women
Published in The FASEB journal (01-04-2013)“…Abstract only We investigated thyroid hormone levels in menopausal BrC patients, and verified the action of triiodothyronine (T3) on genes regulated by…”
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Modulation of thyroid hormone receptors, TRα and TRβ, by using different doses of triiodothyronine (T3) at different times
Published in Arquivos brasileiros de endocrinologia e metabologia (01-07-2013)“…To examine the effect of different doses of triiodothyronine (T3) on mRNA levels of thyroid hormone receptors, TRα and TRβ, at different times. 3T3-L1…”
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