Search Results - "Conchon, Elisabeth"
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Synthesis and Biological Activities of New Checkpoint Kinase 1 Inhibitors Structurally Related to Granulatimide
Published in Journal of medicinal chemistry (20-09-2007)“…In the course of structure−activity relationship studies on granulatimide analogues, new pyrrolo[3,4-c]carbazoles in which the imidazole heterocycle has been…”
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Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of pyrrolo[3,4- a]carbazole-1,3-diones, pyrrolo[3,4- c]carbazole-1,3-diones, and 2-aminopyridazino[3,4- a]pyrrolo[3,4- c]carbazole-1,3,4,7-tetraone
Published in European journal of medicinal chemistry (01-02-2008)“…The synthesis of substituted pyrrolo[3,4- a]carbazole-1,3-diones, pyrrolo[3,4- c]carbazole-1,3-diones, and 2-aminopyridazino[3,4- a]pyrrolo[3,4-…”
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Asymmetric synthesis of 3,5-disubstituted indolizidines by intermolecular addition of an allylsilane on an N-acyliminium ion
Published in Tetrahedron: asymmetry (18-04-2006)“…A diastereoselective synthesis of 3,5-disubstituted indolizidines based on an intermolecular addition of an allylsilane on an acyliminium ion derived from (…”
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Pyrrolocarbazoles as checkpoint 1 kinase inhibitors
Published in Anti-cancer agents in medicinal chemistry (01-08-2008)“…The carbazole framework is found in many natural compounds of biological interest. Indolocarbazoles such as rebeccamycin and staurosporine which are either a…”
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Synthesis, checkpoint kinase 1 inhibitory properties and in vitro antiproliferative activities of new pyrrolocarbazoles
Published in Bioorganic & medicinal chemistry (15-04-2008)“…In the course of structure–activity relationship studies on granulatimide analogues, new pyrrolo[3,4- c]carbazoles have been synthesized in which the imidazole…”
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Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of dipyrrolo[3,4- a:3,4- c]carbazole-triones
Published in Tetrahedron (27-11-2006)“…The syntheses of dipyrrolo[3,4- a:3,4- c]carbazole-1,4,6-triones and dipyrrolo[3,4- a:3,4- c]carbazole-3,4,6-triones are reported. These compounds can be…”
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Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of indolylpyrazolones and indolylpyridazinedione
Published in European journal of medicinal chemistry (01-12-2006)“…The synthesis of 5-indolylpyrazol-3-one, 4-indolylpyrazol-3-one and 4-indolyl-pyridazin-3,6-dione is reported. Their Chk1 inhibitory properties have been…”
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Synthesis, chekpoint kinase 1 inhibitory properties and in vitro antiproliferative activities of new pyrrolocarbazoles
Published in Bioorganic & medicinal chemistry (2008)“…In the course of structure–activity relationship studies on granulatimide analogues, new pyrrolo[3,4-c]carbazoles have been synthesized in which the imidazole…”
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Synthesis, in vitro antiproliferative activities, and Chkl inhibitory properties of pyrrolo[3,4-a]carbazole-1,3-diones, pyrrolo[3,4-c]carbazole-1,3-diones, and 2-aminopyridazino[3,4-a]pyrrolo[3,4-c]carbazole-1,3,4,7-tetraone
Published in European journal of medicinal chemistry (2008)Get full text
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