Search Results - "Conaway, R."

Immune mechanisms orchestrate tertiary lymphoid structures in tumors via cancer-associated fibroblasts by Rodriguez, Anthony B., Peske, J. David, Woods, Amber N., Leick, Katie M., Mauldin, Ileana S., Meneveau, Max O., Young, Samuel J., Lindsay, Robin S., Melssen, Marit M., Cyranowski, Salwador, Parriott, Geoffrey, Conaway, Mark R., Fu, Yang-Xin, Slingluff, Craig L., Engelhard, Victor H.

“…Tumor-associated tertiary lymphoid structures (TA-TLS) are associated with enhanced patient survival and responsiveness to cancer therapies, but the mechanisms…”
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The Adult Calfactant in Acute Respiratory Distress Syndrome Trial by Willson, Douglas F., MD, Truwit, Jonathon D., MD, MBA, Conaway, Mark R., PhD, Traul, Christine S., MD, Egan, Edmund E., MD

“…BACKGROUND Surfactant has been shown to be dysfunctional in ARDS, and exogenous surfactant has proven effective in many forms of neonatal and pediatric acute…”
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Phase I/II adaptive design for drug combination oncology trials by Wages, Nolan A., Conaway, Mark R.

“…Existing statistical methodology on dose finding for combination chemotherapies has focused on toxicity considerations alone in finding a maximum tolerated…”
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Acid ceramidase promotes drug resistance in acute myeloid leukemia through NF-κB-dependent P-glycoprotein upregulation by Tan, Su-Fern, Dunton, Wendy, Liu, Xin, Fox, Todd E., Morad, Samy A.F., Desai, Dhimant, Doi, Kenichiro, Conaway, Mark R., Amin, Shantu, Claxton, David F., Wang, Hong-Gang, Kester, Mark, Cabot, Myles C., Feith, David J., Loughran, Thomas P.

“…Acute myeloid leukemia (AML) is the most common acute leukemia in adults. More than half of older AML patients fail to respond to cytotoxic chemotherapy, and…”
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Screening Echocardiography Identifies Risk Factors for Pulmonary Hypertension at Discharge in Premature Infants with Bronchopulmonary Dysplasia by Madden, B. A., Conaway, M. R., Zanelli, S. A., McCulloch, M. A.

“…Hypothesis Premature infants with bronchopulmonary dysplasia (BPD) are at increased risk of secondary pulmonary hypertension (BPD-PH). Prior studies yielded…”
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Percutaneous Injuries before and after the Needlestick Safety and Prevention Act by Phillips, Elayne K, Conaway, Mark R, Jagger, Janine C

“…According to this analysis of needlestick injuries in a sample of U.S. hospitals before and after passage of the NSPA in 2000, the number of percutaneous…”
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Less is more, or almost as much: A 15-item quality-of-life instrument for myasthenia gravis by Burns, Ted M., Conaway, Mark R., Cutter, Gary R., Sanders, Donald B.

“…We describe the process whereby a recently developed myasthenia gravis (MG)‐specific quality‐of‐life (QOL) instrument was reduced from 60 items to 15 items…”
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Dose-finding design for multi-drug combinations by Wages, Nolan A, Conaway, Mark R, O'Quigley, John

“…Background Most of the current designs used for Phase I dose finding trials in oncology will either involve only a single cytotoxic agent or will impose some…”
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Construction of an efficient evaluative instrument for Myasthenia Gravis: The MG composite by Burns, Ted M., Conaway, Mark R., Cutter, Gary R., Sanders, Donald B.

“…We assessed the performance of items from the Quantitative Myasthenia Gravis (QMG), MMT (Manual Muscle Test), and MG‐ADL (Myasthenia Gravis – Activities of…”
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Rbx1, a Component of the VHL Tumor Suppressor Complex and SCF Ubiquitin Ligase by Kamura, T., Koepp, D. M., Conrad, M. N., Skowyra, D., Moreland, R. J., Iliopoulos, O., Lane, W. S., Kaelin, W. G., Elledge, S. J., Conaway, R. C., Harper, J. W., Conaway, J. W.

“…The von Hippel-Lindau (VHL) tumor suppressor gene is mutated in most human kidney cancers. The VHL protein is part of a complex that includes Elongin B,…”
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Standardizing Prostaglandin Initiation in Prenatally Diagnosed Ductal-Dependent Neonates; A Quality Initiative by Haughey, Brena S., Elliott, Megan R., Wiggin, Jaclyn Y., Conaway, Mark R., White, Shelby C., Swanson, Jonathan R., Dean, Peter N.

“…Prostaglandin E1 (PGE) is used in patients with ductal-dependent congenital heart disease (CHD). Side effects of apnea and fever are often dose dependent and…”
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Endoscopic ultrasound drainage of pancreatic pseudocyst: a prospective comparison with conventional endoscopic drainage by Kahaleh, M, Shami, V M, Conaway, M R, Tokar, J, Rockoff, T, De La Rue, S A, de Lange, E, Bassignani, M, Gay, S, Adams, R B, Yeaton, P

“…Pancreatic pseudocysts are a complication in up to 20% of patients with pancreatitis. Endoscopic management of pseudocysts by a conventional transenteric…”
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Checkpoint Kinase 2 Negatively Regulates Androgen Sensitivity and Prostate Cancer Cell Growth by Ta, Huy Q, Ivey, Melissa L, Frierson, Jr, Henry F, Conaway, Mark R, Dziegielewski, Jaroslaw, Larner, James M, Gioeli, Daniel

“…Prostate cancer is the second leading cause of cancer death in American men, and curing metastatic disease remains a significant challenge. Nearly all patients…”
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Efficacy and complications of covered Wallstents in malignant distal biliary obstruction by Kahaleh, Michel, Tokar, Jeffrey, Conaway, Mark R., Brock, Andrew, Le, Tri, Adams, Reid B., Yeaton, Paul

“…This study evaluated the efficacy and the complications associated with the use of the covered Wallstent in the setting of unresectable malignant biliary…”
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Reduced Expression of Metastasis Suppressor RhoGDI2 Is Associated with Decreased Survival for Patients with Bladder Cancer by THEODORESCU, Dan, SAPINOSO, L. M, CONAWAY, M. R, OXFORD, G, HAMPTON, G. M, FRIERSON, H. F

“…Purpose: RhoGDI2 was recently shown to be a metastasis suppressor gene in models of bladder cancer. We sought to further understand its importance in human…”
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Phosphorylation of RalB Is Important for Bladder Cancer Cell Growth and Metastasis by HONG WANG, OWENS, Charles, CHANDRA, Nidhi, CONAWAY, Mark R, BRAUTIGAN, David L, THEODORESCU, Dan

“…RalA and RalB are monomeric G proteins that are 83% identical in amino acid sequence but have paralogue-specific effects on cell proliferation, metastasis, and…”
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Collateral status, hyperglycemia, and functional outcome after acute ischemic stroke by Arteaga, Daniel F, Ulep, Robin, Kumar, Kevin K, Southerland, Andrew M, Conaway, Mark R, Faber, James, Wintermark, Max, Joyner, David, Sharashidze, Vera, Hirsch, Karen, Giurgiutiu, Dan-Victor, Hannawi, Yousef, Aziz, Yasmin, Shutter, Lori, Visweswaran, Anita, Williams, Alana, Williams, Kori, Gunter, Sonya, Haughey, Heather M, Bruno, Askiel, Johnston, Karen C, Patel, Vishal N

“…Mixed data exist regarding the association between hyperglycemia and functional outcome after acute ischemic stroke when accounting for the impact of…”
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57Zn β-delayed proton emission establishes the 56Ni rp-process waiting point bypass by Saxena, M., -J Ong, W., Meisel, Z., Hoff, D.E.M., Smirnova, N., Bender, P.C., Burcher, S.P., Carpenter, M.P., Carroll, J.J., Chester, A., Chiara, C.J., Conaway, R., Copp, P.A., Crider, B.P., Derkin, J., Estradé, A., Hamad, G., Harke, J.T., Jain, R., Jayatissa, H., Liddick, S.N., Longfellow, B., Mogannam, M., Montes, F., Nepal, N., Ogunbeku, T.H., Richard, A.L., Schatz, H., Soltesz, D., Subedi, S.K., Sultana, I., Tamashiro, A.S., Tripathi, V., Xiao, Y., Zink, R.

“…•In our letter, we address the dominant uncertainty regarding the extent of the rp-process flow bypass around Ni56 waiting point for astrophysical conditions…”
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Prediction of Muscle-invasive Bladder Cancer Using Urinary Proteomics by SCHIFFER, Eric, VLAHOU, Antonia, THEODORESCU, Dan, PETROLEKAS, Andreas, STRAVODIMOS, Konstantinos, TAUBER, Robert, GESCHWEND, Jürgen E, NEUHAUS, Jochen, STOLZENBURG, Jens-Uwe, CONAWAY, Mark R, MISCHAK, Harald

“…Purpose: Minimally invasive methods of predicting the risk of muscle-invasive urothelial bladder carcinoma may expedite appropriate therapy and reduce…”
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Construction and Validation of a Novel Disease-Specific Quality of Life Instrument for Patients with Primary Antibody Deficiency Disease (PADQOL -16) by Ballow, Mark, MD, Conaway, Mark R., PhD, Sriaroon, Panida, MD, Rachid, Rima A., MD, Seeborg, Filiz O., MD, Duff, Carla M., CPNP, MSN, CCRP, Bonilla, Francisco A., MD, PhD, Younger, M. Elizabeth M., CRNP, PhD, Shapiro, Ralph, MD, Burns, Ted M., MD

“…Summary A disease-specific Health-related Quality of Life survey was developed for adult patients with antibody immune deficiency disorders as a tool…”
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