Search Results - "Conant, Genevieve"
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1
A Platform for Generation of Chamber-Specific Cardiac Tissues and Disease Modeling
Published in Cell (07-02-2019)“…Tissue engineering using cardiomyocytes derived from human pluripotent stem cells holds a promise to revolutionize drug discovery, but only if limitations…”
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2
Kinase inhibitor screening using artificial neural networks and engineered cardiac biowires
Published in Scientific reports (18-09-2017)“…Kinase inhibitors are often used as cancer targeting agents for their ability to prevent the activation of cell growth and proliferation signals. Cardiotoxic…”
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3
Biomaterial based cardiac tissue engineering and its applications
Published in Biomedical materials (Bristol) (20-05-2015)“…Cardiovascular disease is a leading cause of death worldwide, necessitating the development of effective treatment strategies. A myocardial infarction involves…”
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Journal Article -
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High-Content Assessment of Cardiac Function Using Heart-on-a-Chip Devices as Drug Screening Model
Published in Stem cell reviews (01-06-2017)“…Drug discovery and development continues to be a challenge to the pharmaceutical industry despite great advances in cell and molecular biology that allow for…”
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Highly Elastic and Moldable Polyester Biomaterial for Cardiac Tissue Engineering Applications
Published in ACS biomaterials science & engineering (09-05-2016)“…Polyester biomaterials are used in tissue engineering as scaffolds for implantation of tissues developed in vitro. An ideal biodegradable elastomer for cardiac…”
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Method for the Fabrication of Elastomeric Polyester Scaffolds for Tissue Engineering and Minimally Invasive Delivery
Published in ACS biomaterials science & engineering (12-11-2018)“…Using the methods described herein, we have demonstrated how scaffolds can be designed for a number of applications including tissue engineering, biomedical…”
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High-throughput analysis of kinase inhibitor drugs on cardiac function using engineered heart tissue constructs
Published in Frontiers in bioengineering and biotechnology (2016)“…Abstract only…”
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High Throughput Screening of Kinase Inhibitor Drugs on Cardiac Function Using Engineered Heart Tissue Constructs
Published 01-01-2017“…Protein kinase inhibitors (KIs) are used as highly specific cancer targeting agents for their ability to prevent kinase molecules from activating signalling…”
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Dissertation