Search Results - "Cona, Maria Silvia"
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Resistance mechanisms to anti-HER2 therapies in HER2-positive breast cancer: Current knowledge, new research directions and therapeutic perspectives
Published in Critical reviews in oncology/hematology (01-07-2019)“…[Display omitted] HER2-positive breast cancer (HER2 + BC) represents 15–20% of all BCs. In the last two decades, the introduction of monoclonal antibodies…”
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The emotional impact of the COVID-19 outbreak on cancer outpatients and their caregivers: results of a survey conducted in the midst of the Italian pandemic
Published in Supportive care in cancer (01-02-2022)“…Introduction The study investigates the emotional discomfort of cancer patients and their caregivers, who need to access the oncology day hospital to receive…”
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Host-Related Factors in the Interplay among Inflammation, Immunity and Dormancy in Breast Cancer Recurrence and Prognosis: An Overview for Clinicians
Published in International journal of molecular sciences (01-03-2023)“…A significant proportion of patients treated for early breast cancer develop medium-term and late distant recurrence. The delayed manifestation of metastatic…”
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Rising incidence of late stage breast cancer after COVID-19 outbreak. Real-world data from the Italian COVID-DELAY study
Published in Breast (Edinburgh) (01-10-2022)“…Breast cancer (BC) patients’ (pts) management was affected by a global reorganization after Coronavirus disease 2019 (COVID-19). Our multicenter study aimed to…”
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Single nucleotide polymorphisms to predict taxanes toxicities and effectiveness in cancer patients
Published in The pharmacogenomics journal (01-08-2021)“…Taxanes are used in the treatment of several solid tumours. Adverse events (AEs) might be influenced by single nucleotide polymorphisms (SNPs) in genes…”
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Ralstonia insidiosa Bacteremia in Patients with Solid Cancer Treated by Means of a Central Venous Catheter
Published in Hygiene (Basel, Switzerland) (17-04-2024)“…Ralstonia spp. are low-virulent environmental Gram-negative bacteria that can cause serious nosocomial infections in immunocompromised patients. We report the…”
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Hospital-Based Influenza and Pneumococcal Vaccination for Cancer Patients on Active Treatment and Their Family Members during the COVID-19 Pandemic in Italy: A Single-Center Experience
Published in Vaccines (Basel) (08-06-2024)“…In patients with cancer, tumor- and treatment-induced immunosuppression are responsible for a four-fold increase in morbidity and mortality caused by influenza…”
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Clinical efficacy of the first two doses of anti‐SARS‐CoV‐2 mRNA vaccines in solid cancer patients
Published in Cancer medicine (Malden, MA) (01-06-2023)“…Introduction Cancer patients are frail individuals, thus the prevention of SARS‐CoV‐2 infection is essential. To date, vaccination is the most effective tool…”
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An overview of immune checkpoint inhibitors in breast cancer
Published in Exploration of targeted anti-tumor therapy (01-01-2020)“…Although breast cancer is not traditionally considered an immunogenic type of tumor, the combination of immunotherapy and chemotherapy has recently emerged as…”
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The neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios predict efficacy of platinum-based chemotherapy in patients with metastatic triple negative breast cancer
Published in Scientific reports (07-06-2018)“…Platinum salts are active against metastatic triple negative breast cancer (mTNBC), and biomarkers to predict their effectiveness are urgently needed. In…”
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Alarming Drop in Early Stage Colorectal Cancer Diagnoses After COVID-19 Outbreak: A Real-World Analysis from the Italian COVID-DELAY Study
Published in The oncologist (Dayton, Ohio) (02-09-2022)“…Abstract Background Coronavirus disease 2019 (COVID-19) has triggered the disruption of health care on a global scale. With Italy tangled up in the pandemic…”
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Fight against cancer in Italy: What patients, caregivers and healthy citizens think about care delivery from National Health System
Published in European journal of cancer care (01-11-2022)“…Objective This survey aimed to analyse healthy citizens (HC), cancer patients and their caregivers (CP&CG) perception about cancer care among six different…”
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Antibody response to three‐dose anti‐SARS‐CoV‐2 mRNA‐vaccination in treated solid cancer patients
Published in International journal of cancer (15-04-2024)“…Solid cancer patients are at higher risk of SARS‐CoV‐2 infection and severe complications. Moreover, vaccine‐induced antibody response is impaired in patients…”
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A proposal of a “ready to use” COVID-19 control strategy in an Oncology ward: Utopia or reality?
Published in Critical reviews in oncology/hematology (01-01-2021)“…[Display omitted] •During COVID-19 pandemic cancer patients are a vulnerable category.•Few data about control infection strategy to ensure a COVID-19 free…”
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Immunogenicity of two doses of BNT162b2 and mRNA‐1273 vaccines for solid cancer patients on treatment with or without a previous SARS‐CoV‐2 infection
Published in International journal of cancer (15-02-2023)“…Previous studies on the immunogenicity of SARS‐CoV‐2 mRNA vaccines showed a reduced seroconversion in cancer patients. The aim of our study is to evaluate the…”
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Abstract PO-087: COVID-19 pandemic in Italy: Social distress and gender imbalance among health care professionals
Published in Clinical cancer research (15-09-2020)“…Abstract Introduction: During the last months coronavirus disease 2019 (COVID-19) has spread abruptly to nearly every country, taking on pandemic proportions…”
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COVID-19 and cancer: How outpatients (pts) and their caregivers (CGs) face to the pandemic—A survey from the midst of the Italian outbreak
Published in Journal of clinical oncology (20-05-2021)“…Abstract only e24119 Background: COVID-19 pandemic led to a reorganization of Health Care System for cancer pts, also because of the application of containment…”
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Patients Selection for Immunotherapy in Solid Tumors: Overcome the Naïve Vision of a Single Biomarker
Published in BioMed research international (01-01-2019)“…Immunotherapy, and in particular immune-checkpoints blockade therapy (ICB), represents a new pillar in cancer therapy. Antibodies targeting Cytotoxic…”
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Pegylated liposomal doxorubicin as first line treatment in aids-related Kaposi's sarcoma: a real-life study
Published in Journal of chemotherapy (Florence) (07-09-2021)“…Despite the introduction of effective combination antiretroviral therapy (cART) AIDS-related Kaposi Sarcoma (AIDS-KS) remains the most common malignancy in HIV…”
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Single-Agent Gemcitabine vs. Carboplatin-Gemcitabine in Advanced Breast Cancer: A Retrospective Comparison of Efficacy and Safety Profiles
Published in Clinical breast cancer (01-04-2019)“…Single-agent gemcitabine is a moderately effective compound in metastatic breast cancer (mBC) treatment. Carboplatin is frequently used in addition to…”
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