Search Results - "Comune Pennacchi, Paula"

A new reconstructed human epidermis for in vitro skin irritation testing by Pedrosa, Tatiana do Nascimento, Catarino, Carolina Motter, Pennacchi, Paula Comune, Assis, Sílvia Romano de, Gimenes, Fabrícia, Consolaro, Márcia Edilaine Lopes, Barros, Silvia Berlanga de Moraes, Maria-Engler, Silvya Stuchi

“…Different models of reconstructed human epidermis (RHE) are currently validated to assess skin irritation in vitro and ultimately to the animal replacement of…”
Get full text

Skin Equivalent Models: Protocols for In Vitro Reconstruction for Dermal Toxicity Evaluation by do Nascimento Pedrosa, Tatiana, Catarino, Carolina Motter, Pennacchi, Paula Comune, de Moraes Barros, Silvia Berlanga, Maria-Engler, Silvya Stuchi

“…This chapter presents the protocols for developing of skin equivalents (SE) and reconstructed human epidermis (RHE) models for dermal toxicity evaluation as an…”
Get more information

Passiflora edulis Leaf Extract: Evidence of Antidiabetic and Antiplatelet Effects in Rats by Salles, Bruno Cesar Correa, Silva, Marcelo Aparecido da, Taniguthi, Lara, Ferreira, Juliane Naiara, Rocha, Claudia Quintino da, Vilegas, Wagner, Dias, Pollyana Hammoud, Pennacchi, Paula Comune, Stella Maris da Silveira Duarte, Rodrigues, Maria Rita, Maísa Ribeiro Pereira Lima Brigagão, Fernanda Borges de Araújo Paula

“…Different Passiflora species have been appointed as a promising herbal medicine due to antioxidant properties; however, their effect on oxidative process…”
Get full text

763 Expanded and activated TILs kill tumor cells enabling IO compound assays by Pennacchi, Paula Comune, Navarro, Paloma, Navas, Verónica García, García, Arántzazu Barquín, Fernández, Elena Sevillano, Llorente, Sergio Ruiz, Rodriguez, Juan Francisco, Yagüe, Monica, Ballesteros, Joan, Primo, Daniel, Donas Jimenez, Jesus Garcia

“…BackgroundThe Tumor Microenvironment (TME) has a key role in solid tumor therapy screening. We have developed a 3D ex vivo immunosuppressive assay mimicking…”
Get full text

WU-NK-101, an enhanced memory natural killer (NK) cell therapy, with cetuximab (Ctx) for the treatment of advanced colorectal cancer (CRC) by Muth, John, Leedom, Tom, Hamil, Alexander, Luukkonen, Lena, Tumala, Brunda, Carter, Alun, Magee, Kristann, Comune Pennacchi, Paula, Primo, Daniel, Kiebish, Michael A., Boocock, David, Vadakekolathu, Jayakumar, Petit, Vincent, Baughman, Jan E., Bhatnagar, Nupur, Cooper, Matthew, Rutella, Sergio, Berrien-Elliot, Melissa, Davidson-Moncada, Jan, Fehniger, Todd A.

“…170 Background: CRC is the 4 th leading cause of global cancer-related deaths, and novel therapeutic strategies for advanced CRC are urgently needed. Adoptive…”
Get full text

Vemurafenib resistance increases melanoma invasiveness and modulates the tumor microenvironment by MMP-2 upregulation by Sandri, Silvana, Faião-Flores, Fernanda, Tiago, Manoela, Pennacchi, Paula Comune, Massaro, Renato Ramos, Alves-Fernandes, Débora Kristina, Berardinelli, Gustavo Noriz, Evangelista, Adriane Feijó, de Lima Vazquez, Vinicius, Reis, Rui Manuel, Maria-Engler, Silvya Stuchi

“…[Display omitted] The BRAFV600E mutation confers constitutive kinase activity and accounts for >90% of BRAF mutations in melanoma. This genetic alteration is a…”
Get full text

Putative Predictors of Response to WU-NK-101, an Allogeneic, Enhanced Memory (ML) Natural Killer (NK) Cell Therapy Product, for Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) by Rutella, Sergio, Cashen, Amanda F., Muth, John, Mathyer, Mary Elizabeth, Carter, Alun James, Tumala, Brunda, Arthur, Laura, Magee, Kristann, Comune Pennacchi, Paula, Gorrochategui, Julian, Petit, Vincent, Primo, Daniel, Blanchard, Dominique, Kiebish, Michael, Bhatnagar, Nupur, Boocock, David, Vadakekolathu, Jayakumar, Cooper, Matthew L, Berrien-Elliott, Melissa M., Davidson-Moncada, Jan K, Fehniger, Todd A.

Get full text

Skin corrosion test: a comparison between reconstructed human epidermis and full thickness skin models by Catarino, Carolina Motter, do Nascimento Pedrosa, Tatiana, Pennacchi, Paula Comune, de Assis, Silvia Romano, Gimenes, Fabrícia, Consolaro, Márcia Edilaine Lopes, de Moraes Barros, Silvia Berlanga, Maria-Engler, Silvya Stuchi

“…[Display omitted] Currently, there is a strong global trend towards the development of in vitro models to replace the use of animals in safety evaluation…”
Get full text

Glycated Reconstructed Human Skin as a Platform to Study the Pathogenesis of Skin Aging by Pennacchi, Paula Comune, de Almeida, Maíra Estanislau Soares, Gomes, Octávio Luís Alves, Faião-Flores, Fernanda, de Araújo Crepaldi, Maria Clara, Dos Santos, Marinilce Fagundes, de Moraes Barros, Silvia Berlanga, Maria-Engler, Silvya Stuchi

“…The advanced glycation end products (AGEs) of proteins are common factors in the pathophysiology of a number of disorders related to aging. The skin generation…”
Get more information

Fibroblasts protect melanoma cells from the cytotoxic effects of doxorubicin by Tiago, Manoela, de Oliveira, Edson Mendes, Brohem, Carla Abdo, Pennacchi, Paula Comune, Paes, Rafael Duarte, Haga, Raquel Brandão, Campa, Ana, de Moraes Barros, Silvia Berlanga, Smalley, Keiran S, Maria-Engler, Silvya Stuchi

“…Melanoma is the most aggressive form of skin cancer and until recently, it was extremely resistant to radio-, immuno-, and chemotherapy. Despite the latest…”
Get more information

Abstract 4669: Targeting hedgehog transcription factors GLI1 and GLI2 restores sensitivity to vemurafenib-resistant human melanoma cells by Faiao-Flores, Fernanda, Alves-Fernandes, Debora Kristina Magalhaes, Pennacchi, Paula Comune, Sandri, Silvana, Vicente, Anna Luiza Silva Almeida, Scapulatempo-Neto, Cristovam, Vazquez, Vinicius de Lima, Reis, Rui Manuel, Smalley, Keiran S., Maria-Engler, Silvya Stuchi

“…Abstract Melanoma represents the deadliest of all skin cancers being responsible for more than 75% of skin cancer-related deaths. Although the results with…”
Get full text

Passiflora edulis leaf extract: evidence of antidiabetic and antiplatelet effects in rats by Salles, Bruno Cesar Correa, Silva, Marcelo Aparecido da, Taniguthi, Lara, Ferreira, Juliane Naiara, Rocha, Claudia Quintino da, Vilegas, Wagner, Dias, Pollyana Hammoud, Pennacchi, Paula Comune, Stella Maris da Silveira Duarte, Rodrigues, Maria Rita, Maísa Ribeiro Pereira Lima Brigagão, Fernanda Borges de Araújo Paula

“…Different Passiflora species have been appointed as a promising herbal medicine due to antioxidant properties; however, their effect on oxidative process…”
Get full text