Search Results - "Compton, Leigh A."

Diagnostic Immunohistochemistry in Cutaneous Neoplasia: An Update by Compton, Leigh A., Murphy, George F., Lian, Christine G.

“…Immunohistochemistry (IHC) is an important adjunct in the diagnosis of neoplastic skin diseases. In addition to the many established IHC markers currently in…”
Get full text

Progressive, edematous plaques, mild pancytopenia, and inflammation by Compton, Leigh A., Jones, Heather A., Vinyard, Connor A., Lee, Yi-Shan, Walter, Matthew J., Yokoyama, Christine C.

Get full text

Porokeratoma treated with topical 5% 5-fluorouracil cream by Li, Steve S., Compton, Leigh A., Nemer, Kathleen M.

Get full text

Eruptive squamous atypia (also known as eruptive keratoacanthoma): Definition of the disease entity and successful management via intralesional 5-fluorouracil by Que, Syril Keena T., Compton, Leigh A., Schmults, Chrysalyne D.

“…Eruptive squamous atypia (ESA), which is an idiopathic, sometimes koebnerizing, proliferation of atypical but well-differentiated keratinocytes (also termed…”
Get full text

Combined Kdm6a and Trp53 Deficiency Drives the Development of Squamous Cell Skin Cancer in Mice by Shea, Lauren K., Akhave, Neal S., Sutton, Leslie A., Compton, Leigh A., York, Conner, Ramakrishnan, Sai Mukund, Miller, Christopher A., Wartman, Lukas D., Chen, David Y.

“…Cutaneous squamous cell carcinoma (cSCC) has among the highest mutation burdens of all cancers, reflecting its pathogenic association with the mutagenic…”
Get full text

Symptomatic vulvar demodicosis: A case report and review of the literature by Hedberg, Matthew L., Chibnall, Rebecca J., Compton, Leigh A.

“…Demodex folliculorum is a mite that commonly inhabits the pilosebaceous units of facial skin, particularly in a perioral and periorbital distribution. While…”
Get full text

Eosinophilic folliculitis, eosinophilic dermatosis of hematologic malignancy and acneiform follicular mucinosis: Two case reports and a review of the literature highlighting the spectrum of histopathology by Bailey, Cedric A. R., Laurain, Douglas A., Sheinbein, David M., Jones, Heather A., Compton, Leigh A., Rosman, Ilana S.

“…Within the literature, there is overlap in the histopathological features described in eosinophilic folliculitis associated with chronic lymphocytic leukemia…”
Get full text

Coronary Vessel Development Is Dependent on the Type III Transforming Growth Factor β Receptor by Compton, Leigh A, Potash, Dru A, Brown, Christopher B, Barnett, Joey V

“…Transforming growth factor (TGF)β receptor III (TGFβR3), or β-glycan, binds all 3 TGFβ ligands and inhibin with high affinity but lacks the serine/threonine…”
Get full text

Eruption of solitary reticulohistiocytoma after intense pulsed light burn by Otchere, Elaine, Wang, Cynthia X., Compton, Leigh A., Nahmias, Zachary

Get full text

Melanoma in a patient with DNMT3A overgrowth syndrome by Chen, David Y, Sutton, Leslie A, Ramakrishnan, Sai Mukund, Duncavage, Eric J, Heath, Sharon E, Compton, Leigh A, Miller, Christopher A, Ley, Timothy J

“…Alterations in epigenetic regulators are increasingly recognized as early events in tumorigenesis; thus, patients with acquired or inherited variants in…”
Get full text

Advances in the Genetic Characterization of Cutaneous Mesenchymal Neoplasms: Implications for Tumor Classification and Novel Diagnostic Markers by Compton, Leigh A, Doyle, Leona A

“…Cutaneous mesenchymal neoplasms often pose significant diagnostic challenges; many such entities are rare or show clinical and histologic overlap with both…”
Get full text

Transforming growth factor‐β induces loss of epithelial character and smooth muscle cell differentiation in epicardial cells by Compton, Leigh A., Potash, Dru A., Mundell, Nathan A., Barnett, Joey V.

“…During embryogenesis, epicardial cells undergo epithelial–mesenchymal transformation (EMT), invade the myocardium, and differentiate into components of the…”
Get full text

Anticancer Therapy SMRT-ens Up: Targeting the BCL6-SMRT Interaction in B Cell Lymphoma by Compton, Leigh A., Hiebert, Scott W.

“…Transcription factors have proven to be difficult targets for the development of small-molecule drugs. In this issue of Cancer Cell, Cerchietti et al. identify…”
Get full text

Advances in the Genetic Characterization of Cutaneous Mesenchymal Neoplasms by Compton, Leigh A., MD, PhD, Doyle, Leona A., MD

“…Abstract Cutaneous mesenchymal neoplasms often pose significant diagnostic challenges; many such entities are rare or show clinical and histologic overlap with…”
Get full text

Coronary vessel development: the epicardium delivers by Olivey, Harold E, Compton, Leigh A, Barnett, Joey V

“…Coronary artery disease accounts for 54% of all cardiovascular disease in the United States. Understanding how coronary vessels develop is likely to uncover…”
Get full text

Primary and immortalized mouse epicardial cells undergo differentiation in response to TGFβ by Austin, Anita F., Compton, Leigh A., Love, Joseph D., Brown, Christopher B., Barnett, Joey V.

“…Cells derived from the epicardium are required for coronary vessel development. Transforming growth factor β (TGFβ) induces loss of epithelial character and…”
Get full text

Isoform-Specific Effects of Charged Residues at Borders of the M1−M2 Loop of the Na,K-ATPase α Subunit by Coppi, Maddalena V, Compton, Leigh A, Guidotti, Guido

“…The Na,K-ATPase is specifically inhibited by the cardiac glycoside, ouabain. Via a largely undefined mechanism, the ouabain affinity of the Na,K-ATPase can be…”
Get full text

Migration and differentiation of epicardial cells stimulated by TGFβ1, TGFβ2, or BMP‐2 do not require the Type III Transforming Growth Factor β receptor by Austin, Anita, Compton, Leigh A, Love, Joseph D, Sanchez, Nora A, Brown, Christopher B, Barnett, Joey V

“…Transforming Growth Factor β (TGFβ) Receptor III (TGFβR3) binds all three TGFβ ligands, inhibin, and Bone Morphogenic Protein‐2 (BMP‐2). Since TGFβ causes…”
Get full text

Type III Transforming Growth Factor‐ β Receptor regulates proliferation and apoptosis in epicardial cells by Sanchez, Nora Sylvia, Austin, Anita F, Compton, Leigh A, Love, Joey D, Barnett, Joey V

“…Abstract only Epicardial cells transform into the myocardium and form coronary vessels. The Type III Transforming Growth Factor‐ β Receptor ( Tgfbr3 ) is…”
Get full text

Transforming Growth Factor‐β stimulates smooth muscle differentiation in epicardial cells lacking the Type III Receptor by Barnett, Joey V., Compton, Leigh A., Love, Joey D., Austin, Anita F.

“…Abstract only Transforming growth factor (TGF) β receptor III (TGFβR3) binds all 3 TGFβ ligands and inhibin with high affinity but lacks the serine/threonine…”
Get full text