Search Results - "Compeer, Matthijs G"

Calcitonin Gene-Related Peptide Terminates Long-Lasting Vasopressor Responses to Endothelin 1 In Vivo by Meens, Merlijn J.P.M.T, Mattheij, Nadine J.A, Nelissen, Jelly, Lemkens, Pieter, Compeer, Matthijs G, Janssen, Ben J.A, De Mey, Jo G.R

“…Slow dissociation of endothelin 1 from its endothelin A receptors is responsible for the long-lasting vasoconstrictor effects of the peptide. We showed…”
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Long-lasting physiological antagonism of calcitonin gene-related peptide towards endothelin-1 in rat mesenteric arteries and human coronary arteries by Labruijere, Sieneke, Compeer, Matthijs G., van den Bogaerdt, Antoon J., van den Brink, Antoinette Maassen, De Mey, Jo G.R., Danser, A.H. Jan, Batenburg, Wendy W.

“…Endothelin-1 causes long-lasting contraction via endothelin type A receptor (ETAR) in isolated rat mesenteric arteries (RMA) that cannot be readily terminated…”
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Stimuli of Sensory-Motor Nerves Terminate Arterial Contractile Effects of Endothelin-1 by CGRP and Dissociation of ET-1/ETA-Receptor Complexes by Meens, Merlijn J. P. M. T., Compeer, Matthijs G., Hackeng, Tilman M., van Zandvoort, Marc A., Janssen, Ben J. A., De Mey, Jo G. R.

“…Background Endothelin-1 (ET-1), a long-acting paracrine mediator, is implicated in cardiovascular diseases but clinical trials with ET-receptor antagonists…”
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ETA -receptor antagonists or allosteric modulators? by De Mey, Jo G.R, Compeer, Matthijs G, Lemkens, Pieter, Meens, Merlijn J.P.M.T

“…The paracrine signaling peptide endothelin-1 (ET1) is involved in cardiovascular diseases, cancer and chronic pain. It acts on class A G-protein-coupled…”
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Assessment of Endothelin-A Receptor Expression in Subcutaneous and Orthotopic Thyroid Carcinoma Xenografts in Vivo Employing Optical Imaging Methods by Büther, Katrin, Compeer, Matthijs G, De Mey, Jo G. R, Schober, Otmar, Schäfers, Michael, Bremer, Christoph, Riemann, Burkhard, Höltke, Carsten

“…Endothelin (ET) receptor dysregulation has been described in a number of pathophysiological processes, including cardiovascular disorders, renal failure, and…”
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Endothelin-1 and -2: Two amino acids matter by Compeer, Matthijs G., Suylen, Dennis P.L., Hackeng, Tilman M., De Mey, Jo G.R.

“…Endothelin-1 (ET-1) and endothelin-2 (ET-2; Trp6Leu7ET-1) are expressed by different cell types, but are considered to display identical pharmacological…”
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Stimuli of sensory-motor nerves terminate arterial contractile effects of endothelin-1 by CGRP and dissociation of ET-1/ET(A)-receptor complexes by Meens, Merlijn J P M T, Compeer, Matthijs G, Hackeng, Tilman M, van Zandvoort, Marc A, Janssen, Ben J A, De Mey, Jo G R

“…Endothelin-1 (ET-1), a long-acting paracrine mediator, is implicated in cardiovascular diseases but clinical trials with ET-receptor antagonists were not…”
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815 DISTINCT MECHANISMS INVOLVED IN INITIATION AND PERSISTENCE OF ENDOTHELIN-1-INDUCED VASOCONSTRICTIONS by Compeer, Matthijs G., Janssen, Ger M.J., De Mey, Jo G.R.

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Physiological and functional antagonism of arterial endothelin A receptor function by Compeer, Matthijs G., Meens, Merlijn J.P.M.T./INS, Janssen, Ger M.J./INS, De Mey, Jo G.R./INS

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Good and bad news about single and dual biphenyl endothelin ETA and angiotensin AT1 receptor antagonists by De Mey, Jo G.R./INS, Compeer, Matthijs G., Vrolijk, Misha F.

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The N‐terminal loop of endothelin: 2 sites to a story by Compeer, Matthijs G, Suylen, Dennis PL, Hackeng, Tilman M, De Mey, Jo GR

“…Abstract only Endothelin‐1 (ET‐1) and (Trp 6 Leu 7 )Endothelin‐1 (ET‐2) are endogenous endothelin A (ET A )‐receptor agonists with comparable affinity and…”
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ET A-receptor antagonists or allosteric modulators? by De Mey, Jo G.R., Compeer, Matthijs G., Lemkens, Pieter, Meens, Merlijn J.P.M.T.

“…The paracrine signaling peptide endothelin-1 (ET1) is involved in cardiovascular diseases, cancer and chronic pain. It acts on class A G-protein-coupled…”
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No Distinct Address and Message Domains Involved in Endothelin‐1/ET A ‐mediated Arterial Contractions by Compeer, Matthijs G, Meens, Merlijn JPMT, Hackeng, Tilman M, De Mey, Jo GR

“…Abstract only…”
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No Distinct Address and Message Domains Involved in Endothelin‐1/ETA‐mediated Arterial Contractions by Compeer, Matthijs G, Meens, Merlijn JPMT, Hackeng, Tilman M, De Mey, Jo GR

“…Objective Many peptidergic GPCR agonists contain distinct binding (address) and activating (message) domains. We evaluated whether this is also the case for…”
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TRP channel activation promotes dissociation of ET‐1/ETA‐complexes and terminates vasoconstriction in rat resistance arteries by Meens, Merlijn JPMT, Compeer, Matthijs G, Zandvoort, Marc A, Hackeng, Tilman M, De Mey, Jo GR

“…Objectives We tested whether TRP channel activation promotes dissociation of ET‐1/ETA‐complexes. Methods 2nd order rat mesenteric arteries were investigated by…”
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TRP channel activation promotes dissociation of ET‐1/ET A ‐complexes and terminates vasoconstriction in rat resistance arteries by Meens, Merlijn JPMT, Compeer, Matthijs G, van Zandvoort, Marc A, Hackeng, Tilman M, De Mey, Jo GR

“…Abstract only…”
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Stimuli of Sensory-Motor Nerves Terminate Arterial Contractile Effects of Endothelin-1 by CGRP and Dissociation of ET-1/ET.sub.A-Receptor Complexes by Meens, Merlijn J. P. M. T, Compeer, Matthijs G, Hackeng, Tilman M, van Zandvoort, Marc A, Janssen, Ben J. A, De Mey, Jo G. R

“…Background Endothelin-1 (ET-1), a long-acting paracrine mediator, is implicated in cardiovascular diseases but clinical trials with ET-receptor antagonists…”
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