Search Results - "Comparone, Antonietta"

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    The activation of lactate dehydrogenase induced by mTOR drives neoplastic change in breast epithelial cells by Manerba, Marcella, Di Ianni, Lorenza, Govoni, Marzia, Comparone, Antonietta, Di Stefano, Giuseppina

    Published in PloS one (23-08-2018)
    “…mTOR kinase and the A isoform of lactate dehydrogenase (LDH-A) are key players controlling the metabolic characteristics of cancer cells. By using cultured…”
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    Metabolic activation triggered by cAMP in MCF-7 cells generates lethal vulnerability to combined oxamate/etomoxir by Manerba, Marcella, Govoni, Marzia, Manet, Ilse, Leale, Antoniofrancesco, Comparone, Antonietta, Di Stefano, Giuseppina

    “…Altered energy metabolism is a biochemical fingerprint of cancer cells, widely recognized as one of the “hallmarks of cancer”. Cancer cells show highly…”
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    Journal Article