Search Results - "Companjen, Arjen"

Validation of Adapted Neutralization Assays Developed to Discriminate Anti-Rabies Virus Activity of Two Different Anti-Rabies Virus Monoclonal Antibodies Administered as a Combination by Companjen, Arjen, Moore, Susan, Boulanger, Bruno, Kostense, Stefan, Marissen, Wilfred

“…Assessment of rabies virus (RABV) neutralizing antibodies in subjects vaccinated or injected with anti-RABV immunoglobulins is central in determination of…”
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Validation of the Rapid Fluorescent Focus Inhibition Test for Rabies Virus-Neutralizing Antibodies in Clinical Samples by KOSTENSE, Stefan, MOORE, Susan, COMPANJEN, Arjen, BAKER, Alexander B. H, MARISSEN, Wilfred E, EYBEN, Rie Von, WEVERLING, Gerrit Jan, HANLON, Cathleen, GOUDSMIT, Jaap

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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European Bioanalysis Forum recommendation on method establishment and bioanalysis of biomarkers in support of drug development by Timmerman, Philip, Herling, Christian, Stoellner, Daniela, Jaitner, Birgit, Pihl, Susanne, Elsby, Karen, Henderson, Neil, Barroso, Begona, Fischmann, Stephanie, Companjen, Arjen, Versteilen, Amanda, Bates, Stewart, Kingsley, Clare, Kunz, Ulrich

“…Biomarkers have become increasingly important in drug development and many bioanalysts are getting involved. Consequently, different views on how to approach…”
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Impact of Recombinant Adenovirus Serotype 35 Priming versus Boosting of a Plasmodium falciparum Protein: Characterization of T- and B-Cell Responses to Liver-Stage Antigen 1 by Rodríguez, Ariane, Goudsmit, Jaap, Companjen, Arjen, Mintardjo, Ratna, Gillissen, Gert, Tax, Dennis, Sijtsma, Jeroen, Weverling, Gerrit Jan, Holterman, Lennart, Lanar, David E, Havenga, Menzo J.E, Radošević, Katarina

“…Prime-boost vaccination regimens with heterologous antigen delivery systems have indicated that redirection of the immune response is feasible. We showed…”
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In vivo evoked specific cell mediated cytotoxicity in carp ( Cyprinus carpio L.) uses mainly a perforin/granzyme-like pathway by Companjen, Arjen, Heinhuis, Bas, Aspers, Kelly, Rombout, Jan

“…A specific cytotoxicity assay has been developed for carp using the Epithelioma Papulosum Cyprini (EPC) cell line as target cells and the release of lactate…”
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CD40 ligation-induced cytokine production in human skin explants is partly mediated via IL-1 by Companjen, Arjen R, van der Wel, Leontine I, Boon, Louis, Prens, Errol P, Laman, Jon D

“…CD40 ligation by CD40 ligand(+) CD4(+) T cells has been claimed to be involved in inflammatory responses in human skin. However, these data are derived from in…”
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A modified ex vivo skin organ culture system for functional studies by COMPANJEN, Arjen R, VAN DER WEL, Leontine I, LIU WEI, LAMAN, Jon D, PRENS, Errol P

“…To investigate the immunological function of cells in normal and diseased skin under conditions approximating the in vivo situation, it is necessary to…”
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The European Bioanalysis Forum community's evaluation, interpretation and implementation of the European Medicines Agency guideline on Bioanalytical Method Validation by van Amsterdam, Peter, Companjen, Arjen, Brudny-Kloeppel, Margarete, Golob, Michaela, Luedtke, Silke, Timmerman, Philip

“…The European Medicines Agency's (EMA) 2011 guideline on bioanalytical method validation (BMV) was evaluated and subsequently intensely discussed by the…”
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Pararosaniline Fixation for Detection of Co-stimulatory Molecules, Cytokines, and Specific Antibody by Schrijver, Ingrid A, Melief, Marie-Jose, van Meurs, Marjan, Companjen, Arjen R, Laman, Jon D

“…Integral immunohistochemical analysis of immune responses in frozen sections requires that, in addition to constitutively expressed membrane CD markers, less…”
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Expression of IL-18 in Human Keratinocytes by Companjen, Arjen R., Prens, Errol, Mee, John B., Groves, Richard W.

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Best practices in performing flow cytometry in a regulated environment: feedback from experience within the European Bioanalysis Forum by der Strate, Barry van, Longdin, Robin, Geerlings, Marie, Bachmayer, Nora, Cavallin, Maria, Litwin, Virginia, Patel, Minesh, Passe-Coutrin, Wilfried, Schoelch, Corinna, Companjen, Arjen, Fjording, Marianne Scheel

“…Flow cytometry is a powerful tool that can be used for the support of (pre)clinical studies. Although various white papers are available that describe the…”
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Addressing the challenges of biomarker calibration standards in ligand-binding assays: a European Bioanalysis Forum perspective by Kunz, Ulrich, Goodman, Joanne, Loevgren, Ulf, Piironen, Timo, Elsby, Karen, Robinson, Paul, Pihl, Susanne, Versteilen, Amanda, Companjen, Arjen, Fjording, Marianne Scheel, Timmerman, Philip

“…The analysis of biomarkers by ligand-binding assays offers significant challenges compared with the bioanalysis of small and large molecule drugs. The presence…”
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EBF recommendation for stability testing of anti-drug antibodies; lessons learned from anti-vaccine antibody stability studies by Pihl, Susanne, Michaut, Lydia, Hendriks, Jenny, Loebbert, Ralf, Ryding, Janka, Nemansky, Martin, Vermet, Laurent, Companjen, Arjen

“…Long- and short-term stability testing of the analyte is one of the key parameters in bioanalytical method validation in support of pharmacokinetics. However,…”
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Managing scientific, technical and regulatory innovation in regulated bioanalysis: a discussion paper from the European Bioanalysis Forum by Timmerman, Philip, Henderson, Neil, Smeraglia, John, Mulder, Hans, Ingelse, Benno, Brudny-Kloeppel, Margarete, Companjen, Arjen

“…On 12-13 June 2012, the European Bioanalysis Forum hosted its third Focus Meeting in Brussels (Belgium). At the meeting, a panel discussion was held on the…”
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Conference Report: AAPS and US FDA Crystal City V Meeting on Quantitative Bioanalytical Method Validation and Implementation: Feedback from The EBF by Smeraglia, John, McDougall, Stuart, Elsby, Karen, Companjen, Arjen, White, Stephen, Golob, Michaela, Brudny-Kloeppel, Margarete, Amsterdam, Peter van, Timmerman, Philip

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Matrix effects in metabolite quantification for MIST assessment: the impact of phospholipid removal and HPLC column particle size by Danaceau, Jonathan, Yu, Hongbin, Chambers, Erin, Fountain, Kenneth J

“…This Research article investigates the impact of phospholipid removal and high-performance liquid chromatography column particle size on the accuracy of…”
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'Less is More': defining modern bioanalysis by Dijksman, Jessica, Timmerman, Philip, Abbott, Richard, Barroso, Begona, Kloeppel, Margarete Brudny, Companjen, Arjen, Golob, Michaela, Gordon, Ben, Herling, Christian, Knutsson, Magnus, Luedtke, Silke, Rasmussen, Birgitte Buur, Stoellner, Daniela, Vieser, Eva, Young, Graeme, van Amsterdam, Peter

“…The 4th Open Symposium of the European Bioanalytical Forum entitled 'Less is More' was held on 16-18 November 2011 at the Hesperia Tower Hotel, Barcelona,…”
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High-level expression from two independent expression cassettes in replication-incompetent adenovirus type 35 vector by Vogels, Ronald, Zuijdgeest, David, van Meerendonk, Michelle, Companjen, Arjen, Gillissen, Gert, Sijtsma, Jeroen, Melis, Irene, Holterman, Lennart, Radosevic, Katarina, Goudsmit, Jaap, Havenga, Menzo J. E

“…1 Crucell Holland BV, PO Box 2048, 2301 CA Leiden, The Netherlands 2 Center of Poverty-Related Communicable Diseases, Academic Medical Center, Amsterdam, The…”
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Increased immunogenicity of recombinant Ad35-based malaria vaccine through formulation with aluminium phosphate adjuvant by Ophorst, Olga J.A.E, Radošević, Katarina, Klap, Jaco M, Sijtsma, Jeroen, Gillissen, Gert, Mintardjo, Ratna, van Ooij, Mark J.M, Holterman, Lennart, Companjen, Arjen, Goudsmit, Jaap, Havenga, Menzo J.E

“…Abstract Previously, we have shown the potency of recombinant Adenovirus serotype 35 viral vaccines (rAd35) to induce strong immune response against the…”
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Expression and immunogenicity of thePlasmodium falciparumcircumsporozoite protein: The role of GPI signal sequence by Ophorst, Olga JAE, Radosevic, Katarina, Ouwehand, Krista, van Beem, Wouter, Mintardjo, Ratna, Sijtsma, Jeroen, Kaspers, Jorn, Companjen, Arjen, Holterman, Lennart, Goudsmit, Jaap, Havenga, Menzo JE

“…Previous studies have shown that the immunogenicity of rodent malaria parasite-derived circumsporozoite protein (CS) can be improved by deleting the…”
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