Search Results - "Compalati, Andrea"
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Ethanol and fatty acids impair lipid homeostasis in an in vitro model of hepatic steatosis
Published in Food and chemical toxicology (01-04-2016)“…Excess ethanol consumption and fatty acid intake lead to a cumulative effect on liver steatosis through still unclear mechanisms. This study aimed to…”
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2
Altered oxidative stress/antioxidant status in blood of alcoholic subjects is associated with alcoholic liver disease
Published in Drug and alcohol dependence (01-10-2014)“…Highlights • Oxidative stress is implicated in pathogenesis of alcoholic liver disease (ALD). • TBARS and antioxidant enzyme activities increased upon ethanol…”
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Triglyceride Mobilization from Lipid Droplets Sustains the Anti-Steatotic Action of Iodothyronines in Cultured Rat Hepatocytes
Published in Frontiers in physiology (12-01-2016)“…Adipose tissue, dietary lipids and de novo lipogenesis are sources of hepatic free fatty acids (FFAs) that are stored in lipid droplets (LDs) as…”
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3,5-Diiodo-L-Thyronine Modifies the Lipid Droplet Composition in a Model of Hepatosteatosis
Published in Cellular physiology and biochemistry (01-01-2014)“…Background/Aims: Fatty acids are the main energy stores and the major membrane components of the cells. In the hepatocyte, fatty acids are esterified to…”
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Effects of binge ethanol on lipid homeostasis and oxidative stress in a rat model of nonalcoholic fatty liver disease
Published in Journal of physiology and biochemistry (01-06-2014)“…Excess fat accumulation renders the liver more vulnerable to ethanol, but it is still unclear how alcohol enhances lipid dysmetabolism and oxidative stress in…”
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“Normal values” for the lymphocyte cytokinesis-block micronucleus cytome parameters: Repeatability and reproducibility in a healthy reference population
Published in The Science of the total environment (20-02-2019)“…The micronucleus test in peripheral blood lymphocytes is the most widely validated technique to evaluate the DNA damage and chromosomal instability in human…”
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The Role of Micronucleus Assay to Detect Genetic Instability in Respiratory Cancer Patients
Published in Journal of environmental pathology, toxicology and oncology (2019)“…Asbestos represents the main risk factor for malignant pleural mesothelioma (PM) even if only a minority of exposed people develop this tumor, suggesting a…”
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