Search Results - "Comoy, Emmanuel E."
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Contrast-enhanced MR microscopy of amyloid plaques in five mouse models of amyloidosis and in human Alzheimer’s disease brains
Published in Scientific reports (10-07-2017)“…Gadolinium (Gd)-stained MRI is based on Gd contrast agent (CA) administration into the brain parenchyma. The strong signal increase induced by Gd CA can be…”
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Experimental transfusion of variant CJD-infected blood reveals previously uncharacterised prion disorder in mice and macaque
Published in Nature communications (02-11-2017)“…Exposure of human populations to bovine spongiform encephalopathy through contaminated food has resulted in <250 cases of variant Creutzfeldt–Jakob disease…”
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Transmission of scrapie prions to primate after an extended silent incubation period
Published in Scientific reports (30-06-2015)“…Classical bovine spongiform encephalopathy (c-BSE) is the only animal prion disease reputed to be zoonotic, causing variant Creutzfeldt-Jakob disease (vCJD) in…”
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Atypical BSE (BASE) transmitted from asymptomatic aging cattle to a primate
Published in PloS one (20-08-2008)“…Human variant Creutzfeldt-Jakob Disease (vCJD) results from foodborne transmission of prions from slaughtered cattle with classical Bovine Spongiform…”
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Encephalopathy induced by Alzheimer brain inoculation in a non-human primate
Published in Acta neuropathologica communications (04-09-2019)“…Alzheimer's disease is characterized by cognitive alterations, cerebral atrophy and neuropathological lesions including neuronal loss, accumulation of…”
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Non-human primates in prion diseases
Published in Cell and tissue research (01-04-2023)“…The fascinating history of prion diseases is intimately linked to the use of nonhuman primates as experimental models, which brought so fundamental and…”
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Evaluation of the zoonotic potential of transmissible mink encephalopathy
Published in Pathogens (Basel) (30-07-2013)“…Successful transmission of Transmissible Mink Encephalopathy (TME) to cattle supports the bovine hypothesis for the still controversial origin of TME…”
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Unexpected prion phenotypes in experimentally transfused animals: predictive models for humans?
Published in Prion (16-08-2018)“…The recently reevaluated high prevalence of healthy carriers (1/2,000 in UK) of variant Creutzfeldt-Jakob Disease (v-CJD), whose blood might be infectious,…”
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Transgenic mouse models expressing human and macaque prion protein exhibit similar prion susceptibility on a strain-dependent manner
Published in Scientific reports (30-10-2019)“…Cynomolgus macaque has been used for the evaluation of the zoonotic potential of prion diseases, especially for classical-Bovine Spongiform Encephalopathy…”
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Evaluation of the protection of primates transfused with variant Creutzfeldt-Jakob disease-infected blood products filtered with prion removal devices: a 5-year update
Published in Transfusion (Philadelphia, Pa.) (01-06-2015)“…BACKGROUND Analysis of archived appendix samples reveals that one in 2000 individuals in the United Kingdom may carry the infectious prion protein associated…”
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Removal of exogenous prion infectivity in leukoreduced red blood cells unit by a specific filter designed for human transfusion
Published in Transfusion (Philadelphia, Pa.) (01-04-2014)“…Background Five cases of variant Creutzfeldt‐Jakob disease (vCJD) infections were attributed to infusion of contaminated blood components, turning to real the…”
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In vivo induction of type 1 and 2 immune responses against protein antigens
Published in International immunology (01-04-1997)“…Polarization of the immune response towards Th1 or Th2 profiles is under the control of several, not yet well known, mechanisms. The present study was…”
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Neuropathology of iatrogenic Creutzfeldt–Jakob disease and immunoassay of French cadaver-sourced growth hormone batches suggest possible transmission of tauopathy and long incubation periods for the transmission of Abeta pathology
Published in Acta neuropathologica (01-02-2018)“…Abeta deposits and tau pathology were investigated in 24 French patients that died from iatrogenic Creutzfeldt–Jakob disease after exposure to cadaver-derived…”
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The prion protein is critical for DNA repair and cell survival after genotoxic stress
Published in Nucleic acids research (30-01-2015)“…The prion protein (PrP) is highly conserved and ubiquitously expressed, suggesting that it plays an important physiological function. However, despite decades…”
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Atypical BSE
Published in PloS one (20-08-2008)“…Background Human variant Creutzfeldt-Jakob Disease (vCJD) results from foodborne transmission of prions from slaughtered cattle with classical Bovine…”
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The house dust mite allergen, Dermatophagoides pteronyssinus, promotes type 2 responses by modulating the balance between IL-4 and IFN-gamma
Published in The Journal of immunology (1950) (01-03-1998)“…A common property of allergens is their potential to generate type 2 cytokine responses. To understand the mechanisms involved in this phenomenon, we have…”
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Infection with Salmonella typhimurium modulates the immune response to Schistosoma mansoni glutathione-S-transferase
Published in Infection and Immunity (01-08-1997)“…Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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