Search Results - "Comley, John C. W"

Structure-activity relationships of antifilarial antimycin analogs: a multivariate pattern recognition study by Selwood, David L, Livingstone, David J, Comley, John C. W, O'Dowd, Alan B, Hudson, Alan T, Jackson, Peter, Jandu, Karamjit S, Rose, Valerie S, Stables, Jeremy N

“…The structure-activity relationships of a series of novel antifilarial antimycin A1 analogues have been investigated by using computational chemistry and…”
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High-Affinity Inhibitors of Dihydrofolate Reductase:  Antimicrobial and Anticancer Activities of 7,8-Dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with Small Molecular Size by Kuyper, Lee F, Baccanari, David P, Jones, Michael L, Hunter, Robert N, Tansik, Robert L, Joyner, Suzanne S, Boytos, Christine M, Rudolph, Sharon K, Knick, Vince, Wilson, H. Robert, Caddell, J. Marc, Friedman, Henry S, Comley, John C. W, Stables, Jeremy N

“…A series of 7,8-dialkylpyrrolo[3,2-f]quinazolines were prepared as inhibitors of dihydrofolate reductase (DHFR). On the basis of an apparent inverse…”
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Artificial infections of Pneumocystis carinii in the SCID mouse and their use in the in vivo evaluation of antipneumocystis drugs by Comley, J C, Sterling, A M

“…A model for the in vivo evaluation of antipneumocystis drugs has been developed in SCID mice infected intratracheally with cryopreserved mouse-derived…”
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