Search Results - "Comisar, Wendy"

Engineering RGD nanopatterned hydrogels to control preosteoblast behavior: A combined computational and experimental approach by Comisar, Wendy A, Kazmers, Nikolas H, Mooney, David J, Linderman, Jennifer J

“…Abstract The adhesion ligand arginine–glycine–aspartic acid (RGD) has been coupled to various materials to be used as tissue culture matrices or cell…”
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A Single Supratherapeutic Dose of Vorinostat Does Not Prolong the QTc Interval in Patients with Advanced Cancer by Munster, Pamela N, Rubin, Eric H, Van Belle, Simon, Friedman, Evan, Patterson, Jaclyn K, Van Dyck, Kristien, Li, Xiadong, Comisar, Wendy, Chodakewitz, Jeffery A, Wagner, John A, Iwamoto, Marian

“…Purpose: This dedicated QTc phase I study, conducted in advanced-stage cancer patients, assessed the effect of a single supratherapeutic dose (800 mg) of…”
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Multi-scale modeling to predict ligand presentation within RGD nanopatterned hydrogels by Comisar, Wendy A., Hsiong, Susan X., Kong, Hyun-Joon, Mooney, David J., Linderman, Jennifer J.

“…The adhesion ligand RGD has been coupled to various materials to be used as tissue culture matrices or cell transplantation vehicles, and recent studies…”
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Nanoscale Adhesion Ligand Organization Regulates Osteoblast Proliferation and Differentiation by Lee, Kuen Yong, Alsberg, Eben, Hsiong, Susan, Comisar, Wendy, Linderman, Jennifer, Ziff, Robert, Mooney, David

“…It was hypothesized that nanoscale adhesion ligand spacing regulates cell adhesion, proliferation, and differentiation, and that this control can be decoupled…”
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A semimechanistic model of the time‐course of release of PTH into plasma following administration of the calcilytic JTT‐305/MK‐5442 in humans by Cabal, Antonio, Mehta, Khamir, Ross, David S, Shrestha, Rajiv P, Comisar, Wendy, Denker, Andrew, Pai, Sudhakar M, Ishikawa, Tomohiro

“…ABSTRACT JTT‐305/MK‐5442 is a calcium‐sensing receptor (CaSR) allosteric antagonist being investigated for the treatment of osteoporosis. JTT‐305/MK‐5442 binds…”
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Safety and Pharmacokinetics of Higher Doses of Caspofungin in Healthy Adult Participants by Migoya, Elizabeth M., Mistry, Goutam C., Stone, Julie A., Comisar, Wendy, Sun, Peng, Norcross, Alisha, Bi, Sheng, Winchell, Gregory A., Ghosh, Kalyan, Uemera, Naoto, Deutsch, Paul J., Wagner, John A.

“…Caspofungin was the first in a new class of antifungal agents (echinocandins) indicated for the treatment of primary and refractory fungal infections. Higher…”
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Pharmacokinetics and safety of twice-daily atazanavir 300 mg and raltegravir 400 mg in healthy individuals by Zhu, Li, Butterton, Joan, Persson, Anna, Stonier, Michele, Comisar, Wendy, Panebianco, Deborah, Breidinger, Sheila, Zhang, Jenny, Bertz, Richard

“…Atazanavir plus raltegravir 300/400 mg twice daily is being explored as a ritonavir- and nucleoside-sparing treatment strategy. The pharmacokinetics and safety…”
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Caspofungin exposure-response relationships in adult patients with mucosal or invasive candidiasis by Comisar, Wendy, Sun, Peng, Li, Susan, Sable, Carole, Schwartz, Michael, Bi, Sheng, Chow, Joseph, Ngai, Angela, Winchell, Gregory, Kartsonis, Nicholas, Stone, Julie

“…Caspofungin is an echinocandin antifungal agent administered once daily as an intravenous infusion. Relationships between caspofungin exposure and clinical…”
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Adhesion ligand nanopatterning influences differentiation of preosteoblast cells: a combined experimental and computational approach by Comisar, Wendy A., Kazmers, Nikolas H., Mooney, David J., Linderman, Jennifer J.

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Controlling osteogenesis through nanoscale organization of adhesion ligand in alginate hydrogels by Comisar, Wendy Ankrom

“…The adhesion ligand RGD (arginine-glycine-aspartic acid) has been coupled to various materials to be used as tissue culture matrices or cell transplantation…”
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