Search Results - "Comer, J E A"

pH-metric logP 10. Determination of liposomal membrane-water partition coefficients of ionizable drugs by AVDEEF, A, BOX, K. J, COMER, J. E. A, HIBBERT, C, TAM, K. Y

“…To investigate a novel approach for the determination of liposomal membrane-water partition coefficients and lipophilicity profiles of ionizable drugs. The…”
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Using measured pKa, LogP and solubility to investigate supersaturation and predict BCS class by Box, K J, Comer, J E A

“…Ionization, lipophilicity and solubility have a profound influence on the transport properties of drug molecules. We will present an overview of why…”
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pH Electrode performance under automated management conditions by COMER, J. E. A, HIBBERT, C

“…pH is frequently measured in laboratories, but to have confidence in the results it is necessary to know that it was measured properly. For an electrode to…”
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Novel ion-selective electrode system for the simultaneous determination of fluoride and calcium in acid solution by Tyler, J E, Comer, J E

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Multiwavelength spectrophotometric determination of acid dissociation constants of ionizable drugs by Allen, R.I., Box, K.J., Comer, J.E.A., Peake, C., Tam, K.Y.

“…A multiwavelength spectrophotometric approach has been developed to determine acid dissociation constants (p K a values) of sparingly soluble drug compounds…”
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pH-metric log P. III: Glass electrode calibration in methanol-water, applied to pKa determination of water-insoluble substances by AVDEEF, A, COMER, J. E. A, THOMSON, S. J

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PH-metric log p 11. pKa determination of water-insoluble drugs in organic solvent-water mixtures by AVDEEF, A, BOX, K. J, COMER, J. E. A, GILGES, M, HADLEY, M, HIBBERT, C, PATTERSON, W, TAM, K. Y

“…The apparent acid dissociation constants (p(s)Ka) of two water-insoluble drugs, ibuprofen and quinine, were determined pH-metrically in acetonitrile water,…”
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Validation of an ion selective electrode system for the analysis of serum fluoride ion by DULY, E. B, LUNEY, S. R, TRINICK, R, MURRAY, J. M, COMER, J. E. A

“…A high impedance unit was developed for use with a fluoride/pH electrode system for the measurement of serum fluoride. The linearity, accuracy, precision and…”
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