Search Results - "Comer, F I"

Reciprocity between O-GlcNAc and O-Phosphate on the Carboxyl Terminal Domain of RNA Polymerase II by Comer, Frank I, Hart, Gerald W

“…The carboxyl terminal domain of RNA polymerase II has multiple essential roles in transcription initiation, promoter clearance, transcript elongation, and the…”
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O-Glycosylation of nuclear and cytosolic proteins. Dynamic interplay between O-GlcNAc and O-phosphate by Comer, F I, Hart, G W

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Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic beta-N-acetylglucosaminidase from human brain by Gao, Y, Wells, L, Comer, F I, Parker, G J, Hart, G W

“…Dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) on Ser/Thr residues is ubiquitous in higher eukaryotes and…”
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Dynamic interplay between O-glycosylation and O-phosphorylation of nucleocytoplasmic proteins: alternative glycosylation/phosphorylation of THR-58, a known mutational hot spot of c-Myc in lymphomas, is regulated by mitogens by Kamemura, Kazuo, Hayes, Bradley K, Comer, Frank I, Hart, Gerald W

“…Previously, we reported that c-Myc is glycosylated by O-linked N-acetylglucosamine at Thr-58, a known phosphorylation site and a mutational hot spot in…”
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Characterization of a Mouse Monoclonal Antibody Specific for O-Linked N-Acetylglucosamine by Comer, Frank I., Vosseller, Keith, Wells, Lance, Accavitti, Mary Ann, Hart, Gerald W.

“…β-O-linked N-acetylglucosamine (O-GlcNAc) is an abundant posttranslational modification of resident nuclear and cytoplasmic proteins in eukaryotes. Increasing…”
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O-GlcNAc and the control of gene expression by Comer, Frank I, Hart, Gerald W

“…Many eukaryotic proteins contain O-linked N-acetylglucosamine (O-GlcNAc) on their serine and threonine side chain hydroxyls. In contrast to classical cell…”
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Localization of the O-GlcNAc transferase and O-GlcNAc-modified proteins in rat cerebellar cortex by Akimoto, Yoshihiro, Comer, Frank I, Cole, Robert N, Kudo, Akihiko, Kawakami, Hayato, Hirano, Hiroshi, Hart, Gerald W

“…O-linked N-acetylglucosamine (O-GlcNAc) is a ubiquitous nucleocytoplasmic protein modification that has a complex interplay with phosphorylation on…”
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Selective Detection and Site-Analysis of O-GlcNAc-Modified Glycopeptides by β-Elimination and Tandem Electrospray Mass Spectrometry by Greis, Kenneth D., Hayes, Bradley K., Comer, Frank I., Kirk, Marion, Barnes, Stephen, Lowary, Todd L., Hart, Gerald W.

“…Over the past decade, a number of nuclear and cytoplasmic proteins have been identified that are modified by singleN-acetylglucosamine residues attached to the…”
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Proton Transfer in the Mechanism of Triosephosphate Isomerase by Harris, Thomas K, Cole, Robert N, Comer, Frank I, Mildvan, Albert S

“…Triosephosphate isomerase (TIM) catalyzes the reversible interconversion of dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (GAP), with…”
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O-GlcNAcylation of key nuclear and cytoskeletal proteins: reciprocity with O-phosphorylation and putative roles in protein multimerization by Hart, Gerald W., Kreppel, Lisa K., Comer, Frank I., Arnold, C.Shane, Snow, Doris M., Ye, Zhengyi, Cheng, Xiaogang, DellaManna, Debbie, Caine, Drury S., Earles, Betty J., Akimoto, Yoshihiro, Cole, Robert N., Hayes, Bradley K.

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O-linked N-acetylglucosamine: the "yin-yang" of Ser/Thr phosphorylation? Nuclear and cytoplasmic glycosylation by Hart, G W, Greis, K D, Dong, L Y, Blomberg, M A, Chou, T Y, Jiang, M S, Roquemore, E P, Snow, D M, Kreppel, L K, Cole, R N

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Phosphoinositides Specify Polarity during Epithelial Organ Development by Comer, Frank I., Parent, Carole A.

“…The molecular mechanisms that integrate cellular polarity with tissue architecture during epithelial morphogenesis are poorly understood. Using a…”
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Enantiomeric synthesis of (+)-BCH-189 [(+)-(2S,5R)-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine] from D-mannose and its anti-HIV activity by Chu, Chung K, Beach, J. Warren, Jeong, Lak S, Choi, Bo G, Comer, Frank I, Alves, Antonio J, Schinazi, Raymond F

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TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium by Lee, Susan, Comer, Frank I, Sasaki, Atsuo, McLeod, Ian X, Duong, Yung, Okumura, Koichi, Yates, 3rd, John R, Parent, Carole A, Firtel, Richard A

“…Dictyostelium cells form a multicellular organism through the aggregation of independent cells. This process requires both chemotaxis and signal relay in which…”
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O-GlcNAc Transferase Is in a Functional Complex with Protein Phosphatase 1 Catalytic Subunits by Wells, Lance, Kreppel, Lisa K., Comer, Frank I., Wadzinski, Brian E., Hart, Gerald W.

“…A hallmark of signal transduction is the dynamic and inducible post-translational modification of proteins. In addition to the well characterized…”
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Phosphoinositide 3-kinase activity controls the chemoattractant-mediated activation and adaptation of adenylyl cyclase by Comer, Frank I, Parent, Carole A

“…The binding of chemoattractants to cognate G protein-coupled receptors activates a variety of signaling cascades that provide spatial and temporal cues…”
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