Search Results - "Combs, Stephanie E."

Integrating Hyperthermia into Modern Radiation Oncology: What Evidence Is Necessary? by Peeken, Jan C, Vaupel, Peter, Combs, Stephanie E

“…Hyperthermia (HT) is one of the hot topics that have been discussed over decades. However, it never made its way into primetime. The basic biological rationale…”
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Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO) by Soffietti, Riccardo, Abacioglu, Ufuk, Baumert, Brigitta, Combs, Stephanie E, Kinhult, Sara, Kros, Johan M, Marosi, Christine, Metellus, Philippe, Radbruch, Alexander, Villa Freixa, Salvador S, Brada, Michael, Carapella, Carmine M, Preusser, Matthias, Le Rhun, Emilie, Rudà, Roberta, Tonn, Joerg C, Weber, Damien C, Weller, Michael

“…The management of patients with brain metastases has become a major issue due to the increasing frequency and complexity of the diagnostic and therapeutic…”
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Advanced-stage pancreatic cancer: therapy options by Werner, Jens, Combs, Stephanie E., Springfeld, Christoph, Hartwig, Werner, Hackert, Thilo, Büchler, Markus W.

“…Although surgery is a requirement for a potential cure from pancreatic cancer, it is usually diagnosed at a late stage, when surgical intervention is not…”
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Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial by Wick, Wolfgang, Prof, Platten, Michael, Prof, Meisner, Christoph, PhD, Felsberg, Jörg, MD, Tabatabai, Ghazaleh, MD, Simon, Matthias, MD, Nikkhah, Guido, Prof, Papsdorf, Kirsten, MD, Steinbach, Joachim P, Prof, Sabel, Michael, MD, Combs, Stephanie E, MD, Vesper, Jan, MD, Braun, Christian, MD, Meixensberger, Jürgen, Prof, Ketter, Ralf, MD, Mayer-Steinacker, Regine, MD, Reifenberger, Guido, Prof, Weller, Michael, Prof

“…Summary Background Radiotherapy is the standard care in elderly patients with malignant astrocytoma and the role of primary chemotherapy is poorly defined. We…”
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Lomeguatrib Increases the Radiosensitivity of MGMT Unmethylated Human Glioblastoma Multiforme Cell Lines by Kirstein, Anna, Schilling, Daniela, Combs, Stephanie E., Schmid, Thomas E.

“…Background: Treatment resistance of glioblastoma multiforme to chemo- and radiotherapy remains a challenge yet to overcome. In particular, the…”
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Comprehensive surgical treatment strategy for spinal metastases by Wagner, Arthur, Haag, Elena, Joerger, Ann-Kathrin, Jost, Philipp, Combs, Stephanie E., Wostrack, Maria, Gempt, Jens, Meyer, Bernhard

“…The management of patients with spinal metastases (SM) requires a multidisciplinary team of specialists involved in oncological care. Surgical management has…”
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First statement on preparation for the COVID-19 pandemic in large German Speaking University-based radiation oncology departments by Combs, Stephanie E, Belka, Claus, Niyazi, Maximilian, Corradini, Stefanie, Pigorsch, Steffi, Wilkens, Jan, Grosu, Anca L, Guckenberger, Matthias, Ganswindt, Ute, Bernhardt, Denise

“…The COVID-19 pandemic is challenging modern radiation oncology. At University Hospitals, we have a mandate to offer high-end treatments to all cancer patients…”
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Increased heat shock protein 70 (Hsp70) serum levels and low NK cell counts after radiotherapy - potential markers for predicting breast cancer recurrence? by Rothammer, Anna, Sage, Eva K, Werner, Caroline, Combs, Stephanie E, Multhoff, Gabriele

“…Breast cancer is the most common invasive tumor in women worldwide and the second cause of cancer-related deaths. After breast conserving surgery the tumor bed…”
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Commentary: Fractionated Proton Beam Radiation Therapy and Hearing Preservation for Vestibular Schwannoma: Preliminary Analysis of a Prospective Phase 2 Clinical Trial by McClelland, 3rd, Shearwood, Combs, Stephanie E, Halasz, Lia M, Lo, Simon S, Shiue, Kevin

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Neuro-oncology management during the COVID-19 pandemic with a focus on WHO grades III and IV gliomas by Bernhardt, Denise, Wick, Wolfgang, Weiss, Stephanie E, Sahgal, Arjun, Lo, Simon S, Suh, John H, Chang, Eric L, Foote, Matthew, Perry, James, Meyer, Bernhard, Vajkoczy, Peter, Wen, Patrick Y, Straube, Christoph, Pigorsch, Steffi, Wilkens, Jan J, Combs, Stephanie E

“…Abstract Background Because of the increased risk in cancer patients of developing complications caused by severe acute respiratory syndrome coronavirus 2…”
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Proton Beam Therapy and Carbon Ion Radiotherapy for Hepatocellular Carcinoma by Apisarnthanarax, Smith, Bowen, Stephen R., Combs, Stephanie E.

“…Charged particle therapy with proton beam therapy (PBT) and carbon ion radiotherapy (CIRT) has emerged as a promising radiation modality to minimize radiation…”
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Glioblastoma Recurrence Patterns After Radiation Therapy With Regard to the Subventricular Zone by Adeberg, Sebastian, MD, König, Laila, MD, Bostel, Tilman, MD, Harrabi, Semi, MD, Welzel, Thomas, MD, Debus, Jürgen, MD, PhD, Combs, Stephanie E., MD

“…Purpose We evaluated the influence of tumor location and tumor spread in primary glioblastoma (GBM), with respect to the subventricular zone (SVZ), on…”
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Deep learning derived tumor infiltration maps for personalized target definition in Glioblastoma radiotherapy by Peeken, Jan C, Molina-Romero, Miguel, Diehl, Christian, Menze, Bjoern H, Straube, Christoph, Meyer, Bernhard, Zimmer, Claus, Wiestler, Benedikt, Combs, Stephanie E

“…Highlights•DTI-derived tissue infiltration maps may improve radiotherapy planning. •Infiltrative tumor volumes overlapped frequently with observed recurrences…”
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Sulforaphane enhances irradiation effects in terms of perturbed cell cycle progression and increased DNA damage in pancreatic cancer cells by Naumann, Patrick, Liermann, Jakob, Fortunato, Franco, Schmid, Thomas E, Weber, Klaus-Josef, Debus, Jürgen, Combs, Stephanie E

“…Sulforaphane (SFN), an herbal isothiocyanate enriched in cruciferous vegetables like broccoli and cauliflower, has gained popularity for its antitumor effects…”
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Clinical evaluation of vertebral body replacement of carbon fiber–reinforced polyetheretherketone in patients with tumor manifestation of the thoracic and lumbar spine by Schwendner, Maximilian, Ille, Sebastian, Kirschke, Jan S., Bernhardt, Denise, Combs, Stephanie E., Meyer, Bernhard, Krieg, Sandro M.

“…Purpose Radiolucent anterior and posterior implants by carbon fiber–reinforced polyetheretherketone (CFR PEEK) aim to improve treatment of primary and…”
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Particle therapy at the Heidelberg Ion Therapy Center (HIT) – Integrated research-driven university-hospital-based radiation oncology service in Heidelberg, Germany by Combs, Stephanie E, Jäkel, Oliver, Haberer, Thomas, Debus, Jürgen

“…Abstract The Heidelberg Ion Therapy Center (HIT) offers treatment of particle therapy with variety of ion species for over 1300 patients yearly. In November…”
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Craniospinal irradiation(CSI) in patients with leptomeningeal metastases: risk-benefit-profile and development of a prognostic score for decision making in the palliative setting by Devecka, Michal, Duma, Marciana Nona, Wilkens, Jan J, Kampfer, Severin, Borm, Kai Joachim, Münch, Stefan, Straube, Christoph, Combs, Stephanie E

“…The aim of our study was to assess the feasibility and oncologic outcomes in patients treated with spinal (SI) or craniospinal irradiation (CSI) in patients…”
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Long-Term Outcome After Radiotherapy in Patients With Atypical and Malignant Meningiomas—Clinical Results in 85 Patients Treated in a Single Institution Leading to Optimized Guidelines for Early Radiation Therapy by Adeberg, Sebastian, Hartmann, Christian, M.D, Welzel, Thomas, M.D, Rieken, Stefan, M.D, Habermehl, Daniel, M.D, von Deimling, Andreas, M.D, Debus, Jürgen, M.D., Ph.D, Combs, Stephanie E., M.D

“…Purpose Previously, we could show that the new World Health Organization (WHO) classification of meningiomas significantly correlated with outcome in patients…”
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Have we achieved adequate recommendations for target volume definitions in anal cancer? A PET imaging based patterns of failure analysis in the context of established contouring guidelines by Dapper, Hendrik, Schiller, Kilian, Münch, Stefan, Peeken, Jan C, Borm, Kai, Weber, Wolfgang, Combs, Stephanie E

“…There are different contouring guidelines for the clinical target volume (CTV) in anal cancer (AC) which vary concerning recommendations for radiation margins…”
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A phase II, randomized, study of weekly APG101+reirradiation versus reirradiation in progressive glioblastoma by Wick, Wolfgang, Fricke, Harald, Junge, Klaus, Kobyakov, Grigory, Martens, Tobias, Heese, Oliver, Wiestler, Benedikt, Schliesser, Maximilian G, von Deimling, Andreas, Pichler, Josef, Vetlova, Elena, Harting, Inga, Debus, Jürgen, Hartmann, Christian, Kunz, Claudia, Platten, Michael, Bendszus, Martin, Combs, Stephanie E

“…Preclinical data indicate anti-invasive activity of APG101, a CD95 ligand (CD95L)-binding fusion protein, in glioblastoma. Patients (N = 91) with glioblastoma…”
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