Search Results - "Comasseto, João V"
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Biocatalysis and biotransformation in Brazil: An overview
Published in Biotechnology advances (01-09-2015)“…This review presents the recent research in biocatalysis and biotransformation in Brazil. Several substrates were biotransformed by fungi, bacteria and plants…”
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2
Stereoselective Bioreduction of α-Azido Ketones by Whole Cells of Marine-Derived Fungi
Published in Marine biotechnology (New York, N.Y.) (01-12-2015)“…Seven strains of marine-derived fungi (Aspergillus sclerotiorum CBMAI 849, Cladosporium cladosporioides CBMAI 857, Penicillium raistrickii CBMAI 931,…”
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3
Tellurium in organic synthesis: a general approach to buteno- and butanolides
Published in Tetrahedron (23-12-2012)“…The naturally occurring butanolides (−)-blastmycinolactol, (+)-blastmycinone, (−)-NFX-2, (+)-antimycinone as well as the four stereoisomers of the butenolide…”
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4
Biotransformations on organic selenides and tellurides: synthetic applications
Published in Tetrahedron (10-10-2009)“…[Display omitted] Chemical transformations promoted by enzymes in organic selenides and tellurides are reviewed…”
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5
Tellurium in organic synthesis: a general approach to buteno- and butanolides
Published in Tetrahedron (07-10-2012)“…The naturally occurring butanolides (−)-blastmycinolactol, (+)-blastmycinone, (−)-NFX-2, (+)-antimycinone as well as the four stereoisomers of the butenolide…”
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6
Synthetic organotelluride compounds induce the reversal of Pdr5p mediated fluconazole resistance in Saccharomyces cerevisiae
Published in BMC microbiology (26-07-2014)“…Resistance to fluconazole, a commonly used azole antifungal, is a challenge for the treatment of fungal infections. Resistance can be mediated by…”
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7
Selenium and tellurium chemistry: historical background
Published in Journal of the Brazilian Chemical Society (2010)“…In this paper we present a general survey on the history of the selenium and tellurium chemistry in Brazil and worldwide…”
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8
An alternative approach for the synthesis of aryl–alkyl tellurides: reaction of aryl iodides with metal alkyltellurolates promoted by CuI
Published in Tetrahedron (11-11-2011)“…Aryl iodides react with metal organotellurolates in tetrahydrofuran/dimethylformamide in the presence of CuI (5 mol %) or CuI (5 mol %) and 1,10-phenanthroline…”
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9
Stability Study of Hypervalent Tellurium Compounds in Aqueous Solutions
Published in ACS omega (31-08-2017)“…Hypervalent tellurium compounds (telluranes) are promising therapeutical agents with negligible toxicities for some diseases in animal models. The C–Te bond of…”
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10
Stereocontrolled Synthesis of (−)-Macrolactin A
Published in Journal of the American Chemical Society (27-02-2002)“…The total synthesis of (−)-macrolactin A, a 24-membered macrolide, has been achieved using a newly developed 1,3-diol synthon for the introduction of two key…”
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11
Metallic chalcogenolates mediated modular Michael-aldol cascade reaction: an easy route to multi-functionalized chalcogenides and Morita–Baylis–Hillman adducts
Published in Tetrahedron (23-12-2012)“…Chalcogenolate mediated Michael-aldol cascade reactions consists of a very efficient route to multi-functionalized γ-hydroxichalcogenides. Although, when…”
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12
A tellurium-based cathepsin B inhibitor: Molecular structure, modelling, molecular docking and biological evaluation
Published in Journal of molecular structure (11-04-2012)“…► Tellurium compounds display pharmaceutical potential. ► Cathepsin B is a likely target for thiophilic tellurium. ► Intramolecular Te⋯O(carbonyl) contacts…”
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13
Antiproliferative and ultrastructural effects of phenethylamine derivatives on promastigotes and amastigotes of Leishmania ( Leishmania ) infantum chagasi
Published in Parasitology international (01-04-2017)“…Abstract Leishmania ( Leishmania ) infantum chagasi is one of the agents that cause visceral leishmaniasis. This disease occurs more frequently in third world…”
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14
Tellurium-based cysteine protease inhibitors: evaluation of novel organotellurium(IV) compounds as inhibitors of human cathepsin B
Published in Bioorganic & medicinal chemistry letters (01-02-2005)“…The inhibition of Cathepsin B by a sort of different classes of organotellurium(IV) compounds was described. New organotellurium(IV) compounds with specific…”
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15
Novel cross-coupling reactions between organotellurides and Grignard reagents employing a MnCl2/CuI catalytic system
Published in Tetrahedron letters (11-07-2012)“…We present a general protocol for the cross-coupling reaction of Grignard reagents and organic tellurides. Aryl Grignard reagents react stereospecifically with…”
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16
A new approach to organomanganese compounds: the tellurium/manganese exchange reaction
Published in Tetrahedron letters (13-10-2010)“…Diorganomanganese compounds react with aryl, vinyl, and alkynyl tellurides in a tellurium/manganese exchange reaction. The new mixed organomanganese reagents…”
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17
Reactive organometallics from organotellurides: application in organic synthesis
Published in Journal of the Brazilian Chemical Society (2010)“…In this paper the preparation of reactive organometallics starting from organotellurides is reviewed. The application of the reactive organometallics prepared…”
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18
Irreversible inhibition of human cathepsins B, L, S and K by hypervalent tellurium compounds
Published in Biological chemistry (01-11-2009)“…The inhibition of human cysteine cathepsins B, L, S and K was evaluated by a set of hypervalent tellurium compounds (telluranes) comprising both organic and…”
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19
Enzymatic kinetic resolution of organochalcogenides in supercritical CO2
Published in Tetrahedron letters (29-06-2011)“…1-(Phenylthio)-, 1-(phenylseleno)- and 1-(phenyltelluro)-propan-2-ol were efficiently resolved by CAL-B in sc-CO2…”
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20
N-Functionalized organolithium compounds via tellurium/lithium exchange reaction
Published in Journal of the Brazilian Chemical Society (2010)“…A set of tellurium amines have been evaluated in the tellurium/lithium exchange reaction. The nitrogen-containing organolithium compounds were efficiently…”
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