Search Results - "Colvin, Teresa"
-
1
The Neuroprotective Effect of Klotho is Mediated via Regulation of Members of the Redox System
Published in The Journal of biological chemistry (29-08-2014)“…Generation of reactive oxygen species (ROS), leading to oxidative damage and neuronal cell death, plays an important role in the pathogenesis of…”
Get full text
Journal Article -
2
Cardiac Toxicity Associated with Immune Checkpoint Inhibitors: Case Series and Review of the Literature
Published in Case reports in oncology (01-01-2019)“…The development of immune checkpoint inhibitors (ICIs) has revolutionized the treatment of patients with advanced stage cancers. However, immune-related…”
Get full text
Journal Article -
3
Hsp70-Bag3 Interactions Regulate Cancer-Related Signaling Networks
Published in Cancer research (Chicago, Ill.) (01-09-2014)“…Bag3, a nucleotide exchange factor of the heat shock protein Hsp70, has been implicated in cell signaling. Here, we report that Bag3 interacts with the SH3…”
Get full text
Journal Article -
4
Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer
Published in Molecular cancer therapeutics (01-03-2015)“…Hsp70 is a stress-inducible molecular chaperone that is required for cancer development at several steps. Targeting the active site of Hsp70 has proven…”
Get full text
Journal Article -
5
Anticancer Effects of Targeting Hsp70 in Tumor Stromal Cells
Published in Cancer research (Chicago, Ill.) (15-10-2016)“…The stress-induced chaperone protein Hsp70 enables the initiation and progression of many cancers, making it an appealing therapeutic target for development…”
Get full text
Journal Article -
6
Proteotoxicity is not the reason for the dependence of cancer cells on the major chaperone Hsp70
Published in Cell cycle (Georgetown, Tex.) (15-07-2014)“…Several years ago a hypothesis was proposed that the survival of cancer cells depend on elevated expression of molecular chaperones because these cells are…”
Get full text
Journal Article -
7
All-trans-retinoic-acid and arsenic trioxide induced remission in promyelocytic blast crisis
Published in Leukemia research reports (01-01-2018)“…A 78-year-old-male with chronic myeloid leukemia (CML) treated for seven years with dasatinib developed an acute promyelocytic leukemia complicated by…”
Get full text
Journal Article -
8
Anti-cancer effects of targeting Hsp70 in tumor stromal cells
Published in Cancer research (Chicago, Ill.) (08-08-2016)“…The stress-induced chaperone protein Hsp70 enables the initiation and progression of many cancers, making it an appealing therapeutic target for development…”
Get full text
Journal Article -
9
The heat shock protein HSP70 affects cancer signaling via its interaction with co-chaperone BAG3
Published 01-01-2014“…HSP70 plays an important role in cancer development. However, the molecular role of HSP70 in cancer is poorly understood. Previous work from our laboratory…”
Get full text
Dissertation -
10
The heat shock protein HSP70 affects cancer signaling via its interaction with co-chaperone BAG3
Get full text
Dissertation -
11
All-trans-retinoic-acid and arsenic trioxide induced remission in promyelocytic blast crisis
Published in Leukemia research reports (01-01-2018)Get full text
Report -
12
Cardiac Toxicity Associated with Immune Checkpoint Inhibitors: Case Series and Review of the Literature
Published in Case reports in oncology (01-01-2019)Get full text
Report