Search Results - "Colucci, W"

Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway by COMMUNAL, C, SINGH, K, PIMENTEL, D. R, COLUCCI, W. S

“…Myocardial sympathetic activity is increased in heart failure. We tested the hypothesis that norepinephrine (NE) stimulates apoptosis in adult rat ventricular…”
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Molecular and Cellular Mechanisms of Myocardial Failure by Colucci, Wilson S

“…Myocardial remodeling is a central feature in the progression of myocardial failure. This process, which can be stimulated by factors that are increased as a…”
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Effects of levosimendan on cardiac remodeling and cardiomyocyte apoptosis in hypertensive Dahl/Rapp rats by Louhelainen, M, Vahtola, E, Kaheinen, P, Leskinen, H, Merasto, S, Kytö, V, Finckenberg, P, Colucci, W S, Levijoki, J, Pollesello, P, Haikala, H, Mervaala, E M A

“…Background and purpose: Progression of heart failure in hypertensive Dahl rats is associated with cardiac remodeling and increased cardiomyocyte apoptosis…”
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The Effect of Carvedilol on Morbidity and Mortality in Patients with Chronic Heart Failure by Packer, Milton, Bristow, Michael R, Cohn, Jay N, Colucci, Wilson S, Fowler, Michael B, Gilbert, Edward M, Shusterman, Neil H

“…Activation of the sympathetic nervous system is one of the cardinal pathophysiologic abnormalities in patients with chronic heart failure. Levels of…”
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Nitric oxide, atrial natriuretic peptide, and cyclic GMP inhibit the growth-promoting effects of norepinephrine in cardiac myocytes and fibroblasts by Calderone, A, Thaik, C M, Takahashi, N, Chang, D L, Colucci, W S

“…This study tested the hypothesis that nitric oxide (NO) and atrial natriuretic peptide (ANP) can attenuate the effects of adrenergic agonists on the growth of…”
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Targeted anticytokine therapy in patients with chronic Heart failure: Results of the Randomized Etanercept Worldwide Evaluation (RENEWAL) by MANN, Douglas L, MCMURRAY, John J. V, KRUM, Henry, LIU, Peter, NIEMINEN, Markku, TAVAZZI, Luigi, VAN VELDHUISEN, Dirk Jan, WALDENSTROM, Anders, WARREN, Marshelle, WESTHEIM, Arne, ZANNAD, Faiez, FLEMING, Thomas, PACKER, Milton, SWEDBERG, Karl, BORER, Jeffrey S, COLUCCI, Wilson S, DJIAN, Jacques, DREXLER, Helmut, FELDMAN, Arthur, KOBER, Lars

“…Studies in experimental models and preliminary clinical experience suggested a possible therapeutic role for the soluble tumor necrosis factor antagonist…”
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Inhibition of Copper-Zinc Superoxide Dismutase Induces Cell Growth, Hypertrophic Phenotype, and Apoptosis in Neonatal Rat Cardiac Myocytes In Vitro by Siwik, Deborah A, Tzortzis, John D, Pimental, David R, Chang, Donny L.-F, Pagano, Patrick J, Singh, Krishna, Sawyer, Douglas B, Colucci, Wilson S

“…Oxidative stress has been implicated in the pathophysiology of myocardial failure. We tested the hypothesis that inhibition of endogenous antioxidant enzymes…”
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Sustained hemodynamic effects of intravenous levosimendan by KIVIKKO, Matti, LEHTONEN, Lasse, COLUCCI, Wilson S

“…The short-term infusion of levosimendan (Levo) improves hemodynamic function in patients with decompensated heart failure. The metabolites of Levo have a…”
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Apoptosis in the Heart by Colucci, Wilson S

“…Apoptosis (or programmed cell death) is a central feature of normal tissue development in the fetus and of cell replacement in certain adult tissues (e.g., the…”
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Akt3 overexpression in the heart results in progression from adaptive to maladaptive hypertrophy by Taniyama, Yoshiaki, Ito, Masahiro, Sato, Kaori, Kuester, Christoph, Veit, Kerstin, Tremp, Gunter, Liao, Ronglih, Colucci, Wilson S., Ivashchenko, Yuri, Walsh, Kenneth, Shiojima, Ichiro

“…Akt is a serine/threonine kinase that mediates a variety of cellular responses to external stimuli. Among the three members of mammalian Akt (Akt1, Akt2 and…”
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Acute endothelin a receptor blockade causes selective pulmonary vasodilation in patients with chronic heart failure by GIVERTZ, M. M, COLUCCI, W. S, LEJEMTEL, T. H, GOTTLIEB, S. S, HARE, J. M, SLAWSKY, M. T, LEIER, C. V, LOH, E, NICKLAS, J. M, LEWIS, B. E

“…Elevated plasma endothelin-1 (ET-1) levels in patients with chronic heart failure correlate with pulmonary artery pressures and pulmonary vascular resistance…”
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Nesiritide for the treatment of decompensated heart failure by Colucci, Wilson S.

“…Nesiritide (human recombinant B-type natriuretic peptide) binds to receptors in the vasculature, kidney, and other organs to mimic the actions of endogenous…”
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Effect of nozzle geometry on local convective heat transfer to a confined impinging air jet by COLUCCI, D. W, VISKANTA, R

“…This article reports results on the effects of hyperbolic nozzle geometry on the local heat-transfer coefficients for confined impinging air jets. A…”
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Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts by Siwik, D A, Pagano, P J, Colucci, W S

“…Oxidative stress has been implicated in the pathophysiology of myocardial failure. We tested the hypothesis that oxidative stress can regulate extracellular…”
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Secondary pulmonary hypertension in chronic heart failure : The role of the endothelium in pathophysiology and management by MORAES, Denzil L, COLUCCI, Wilson S, GIVERTZ, Michael M

“…Pulmonary vascular resistance is frequently elevated in patients with chronic left ventricular failure as a result of dysregulation of vascular smooth muscle…”
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Interleukin-1 beta modulates the growth and phenotype of neonatal rat cardiac myocytes by Thaik, C M, Calderone, A, Takahashi, N, Colucci, W S

“…Mononuclear cell infiltration and local cytokine elaboration are hallmarks of inflammatory and immunologic heart diseases. To test the hypothesis that…”
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Increased sensitivity to nitric oxide synthase inhibition in patients with heart failure: Potentiation of β-adrenergic inotropic responsiveness by HARE, J. M, GIVERTZ, M. M, CREAGER, M. A, COLUCCI, W. S

“…We previously showed that cardiac nitric oxide (NO) inhibits the positive inotropic response to beta-adrenergic stimulation in humans with left ventricular…”
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β-Adrenergic Receptor–Stimulated Apoptosis in Cardiac Myocytes Is Mediated by Reactive Oxygen Species/c-Jun NH2-Terminal Kinase–Dependent Activation of the Mitochondrial Pathway by Remondino, Andrea, Kwon, Susan H, Communal, Catherine, Pimentel, David R, Sawyer, Douglas B, Singh, Krishna, Colucci, Wilson S

“…Stimulation of β-adrenergic receptors (βARs) causes apoptosis in adult rat ventricular myocytes (ARVMs). The role of reactive oxygen species (ROS) in mediating…”
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Interleukin-1β and Tumor Necrosis Factor-α Decrease Collagen Synthesis and Increase Matrix Metalloproteinase Activity in Cardiac Fibroblasts In Vitro by Siwik, Deborah A, Chang, Donny L.-F, Colucci, Wilson S

“…We tested the hypothesis that the inflammatory cytokines can regulate fibroblast extracellular matrix metabolism. Neonatal and adult rat cardiac fibroblasts…”
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Clinical and echocardiographic correlates of plasma osteopontin in the community: the Framingham Heart Study by Ärnlöv, J, Evans, J C, Benjamin, E J, Larson, M G, Levy, D, Sutherland, P, Siwik, D A, Wang, T J, Colucci, W S, Vasan, R S

“…[...]we investigated the clinical and echocardiographic correlates of plasma osteopontin in a community-based sample. All models are adjusted for age, sex,…”
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