Search Results - "Colosi, P"
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Quantitative Single-Molecule Localization Microscopy
Published in Annual review of biophysics (09-05-2023)“…Super-resolution fluorescence microscopy allows the investigation of cellular structures at nanoscale resolution using light. Current developments in…”
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2
α-Synuclein colocalizes with AP180 and affects the size of clathrin lattices
Published in The Journal of biological chemistry (01-09-2023)“…α-Synuclein and family members β- and γ-synuclein are presynaptic proteins that sense and generate membrane curvature, properties important for synaptic…”
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3
Intravitreal delivery of AAV8 retinoschisin results in cell type-specific gene expression and retinal rescue in the Rs1-KO mouse
Published in Gene therapy (01-07-2009)“…X-linked juvenile retinoschisis (XLRS) is a neurodevelopmental abnormality caused by retinoschisin gene mutations. XLRS is characterized by splitting through…”
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4
Piggybacking functionalized DNA nanostructures into live-cell nuclei
Published in Science advances (05-07-2024)“…DNA origami nanostructures (DOs) are promising tools for applications including drug delivery, biosensing, detecting biomolecules, and probing chromatin…”
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5
Efficiency of eight different AAV serotypes in transducing rat myocardium in vivo
Published in Gene therapy (01-07-2007)“…Recombinant adeno-associated (AAV) viruses have unique properties, which make them ideal vectors for gene transfer targeting the myocardium. Numerous serotypes…”
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6
Inhibition of pathological brain angiogenesis through systemic delivery of AAV vector expressing soluble FLT1
Published in Gene therapy (01-11-2015)“…The soluble vascular endothelial growth factor (VEGF) receptor 1 (sFLT1) has been tested in both animals and humans for anti-angiogenic therapies, for example,…”
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7
Adeno-associated virus vectors can be efficiently produced without helper virus
Published in Gene therapy (01-07-1998)“…The purpose of this work was to develop an efficient method for the production of adeno-associated virus (AAV) vectors in the absence of helper virus. The…”
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8
Intravitreal delivery of AAV8 retinoschisin results in cell type-specific gene expression and retinal rescue in the Rs1-KO mouse
Published in Gene therapy (01-07-2009)Get full text
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9
Gene Delivery to Skeletal Muscle Results in Sustained Expression and Systemic Delivery of a Therapeutic Protein
Published in Proceedings of the National Academy of Sciences - PNAS (26-11-1996)“…Somatic gene therapy has been proposed as a means to achieve systemic delivery of therapeutic proteins. However, there is limited evidence that current methods…”
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10
Mechanism-based design of prolactin receptor antagonists
Published in The Journal of biological chemistry (15-03-1993)“…The mechanism of action of two forms of the prolactin (PRL) receptor was studied using analogs of human growth hormone (hGH). At low concentrations…”
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11
Mutational analysis of the intracellular domain of the human growth hormone receptor
Published in The Journal of biological chemistry (15-06-1993)“…The human growth hormone (GH) receptor contains an extracellular hormone-binding domain of about 246 amino acids, a single transmembrane domain, and a…”
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12
Gene therapy against an experimental glioma using adeno-associated virus vectors
Published in Gene therapy (01-11-1996)“…The efficacy of gene therapy for glioma was examined using adeno-associated virus (AAV)-based vectors to deliver genes to experimental tumors in mice…”
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13
Molecular cloning of mouse placental lactogen cDNA
Published in Proceedings of the National Academy of Sciences - PNAS (01-11-1986)“…We have isolated a cDNA clone for the 23-kDa mouse placental lactogen II (mPL-II) from a phage λ gt11 expression library containing cDNA synthesized from…”
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14
Mouse placental lactogen-I: RIA and gestational profile in maternal serum
Published in Endocrinology (Philadelphia) (01-11-1989)“…A RIA for mouse placental lactogen-I (mPL-I) was developed using recombinant mPL-I as the standard, radioligand, and antigen for antiserum production…”
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15
Mutations on the External Surfaces of Adeno-Associated Virus Type 2 Capsids That Affect Transduction and Neutralization
Published in Journal of Virology (01-01-2006)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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16
Robust, But Transient Expression of Adeno-Associated Virus-Transduced Genes During Human T Lymphopoiesis
Published in Blood (15-12-1997)“…Recombinant adeno-associated viruses (rAAV) have been proposed to be gene transfer vehicles for hematopoietic stem cells with advantages over other virus-based…”
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17
PDGF-CC blockade inhibits pathological angiogenesis by acting on multiple cellular and molecular targets
Published in Proceedings of the National Academy of Sciences - PNAS (06-07-2010)“…The importance of identifying VEGF-independent pathways in pathological angiogenesis is increasingly recognized as a result of the emerging drug resistance to…”
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Isolation, Purification, and Characterization of Mouse Placental Lactogen
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-1982)“…Mouse placental lactogen was purified 1840-fold from BALB/c placentae from days 14-18 of gestation with an overall yield of 29%. The purification procedure…”
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19
Preclinical in vivo evaluation of pseudotyped adeno-associated virus vectors for liver gene therapy
Published in Blood (01-10-2003)“…We report the generation and use of pseudotyped adeno-associated viral (AAV) vectors for the liver-specific expression of human blood coagulation factor IX…”
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20
Lactogenic response of cultured mouse mammary epithelial cells to mouse placental lactogen
Published in Journal of endocrinology (01-05-1986)“…The ability of mouse placental lactogen (mPL), mouse prolactin (mPRL), mouse GH (mGH) and ovine prolactin (oPRL) to stimulate synthesis of alpha-lactalbumin…”
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