Search Results - "Colon, Mariano"

Transcriptome and proteome dynamics of cervical remodeling in the mouse during pregnancy by Nallasamy, Shanmugasundaram, Palacios, Hector H, Setlem, Rohit, Caraballo, Mariano Colon, Li, Kelvin, Cao, Edward, Shankaran, Mahalakshmi, Hellerstein, Marc, Mahendroo, Mala

“…During gestation, the female reproductive tract must maintain pregnancy while concurrently preparing for parturition. Here, we explore the transitions in gene…”
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Human Endometriosis Tissue Microarray Reveals Site-specific Expression of Estrogen Receptors, Progesterone Receptor, and Ki67 by Colón-Caraballo, Mariano, García, Miosotis, Mendoza, Adalberto, Flores, Idhaliz

“…Most available therapies for endometriosis are hormone-based and generally broadly used without taking into consideration the ovarian hormone receptor…”
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Dynamic states of cervical epithelia during pregnancy and epithelial barrier disruption by Cooley, Anne, Madhukaran, ShanmugaPriyaa, Stroebele, Elizabeth, Colon Caraballo, Mariano, Wang, Lei, Akgul, Yucel, Hon, Gary C., Mahendroo, Mala

“…The cervical epithelium undergoes changes in proliferation, differentiation, and function that are critical to ensure fertility and maintain pregnancy. Here,…”
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H3K27me3 is an Epigenetic Mark of Relevance in Endometriosis by Colón-Caraballo, Mariano, Monteiro, Janice B, Flores, Idhaliz

“…Epigenetic mechanisms may play an important role in the etiology of endometriosis. The modification of histones by methylation of lysine residues has been…”
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Pharmacological blockage of the CXCR4-CXCL12 axis in endometriosis leads to contrasting effects in proliferation, migration, and invasion by Ruiz, Abigail, Ruiz, Lynnette, Colón-Caraballo, Mariano, Torres-Collazo, Bryan J, Monteiro, Janice B, Bayona, Manuel, Fazleabas, Asgerally T, Flores, Idhaliz

“…High levels of inflammatory factors including chemokines have been reported in peritoneal fluid and blood of women with endometriosis. CXCL12 mediates its…”
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Endometriosis is characterized by a distinct pattern of histone 3 and histone 4 lysine modifications by Monteiro, Janice B, Colón-Díaz, Maricarmen, García, Miosotis, Gutierrez, Sylvia, Colón, Mariano, Seto, Edward, Laboy, Joaquín, Flores, Idhaliz

“…The histone modification patterns in endometriosis have not been fully characterized. This gap in knowledge results in a poor understanding of the epigenetic…”
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Targeting of the Histone 3 Lysine 9 Methyltransferase Pathway in Kras‐Induced Cell Growth and Pancreatic Cancer by Lomberk, Gwen, Urrutia, Guillermo, Caraballo, Mariano Colon, Salmonson, Ann, Missfeldt, Mckenna, Mathison, Angela, Tsai, Susan, Adsay, Nazmi Volkan, Evans, Douglas, Iovanna, Juan, Urrutia, Raul

“…Pancreatic ductular adenocarcinoma (PDAC) ranks fourth as a cause of cancer death in the USA and is almost universally fatal, with the annual number of deaths…”
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CXCR4‐CXCL12 axis in proliferation, migration, and invasion of endometriosis (LB850) by Ruiz‐Rivera, Abigail, Monteiro, Janice, Colon, Mariano, Echevarria, Martha, Fazleabas, Asgerally, Flores, Idhaliz

“…Endometriosis a benign gynaecological disease, associated with chronic inflammation and increased levels of chemokines. Lesions are composed of endometrial…”
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Effects of histone methyltransferase inhibition in endometriosis by Colón-Caraballo, Mariano, Torres-Reverón, Annelyn, Soto-Vargas, John Lee, Young, Steven L, Lessey, Bruce, Mendoza, Adalberto, Urrutia, Raúl, Flores, Idhaliz

“…Although the histone methyltransferase EZH2 and its product H3K27me3 are well studied in cancer, little is known about their role and potential as therapeutic…”
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CXCL12α induces proliferation and migration of endometrial epithelial cells expressing CXCR4 by Ruiz, Abigail, Monteiro, Janice, Colon, Mariano, Echevarria, Martha, Morales, Luisa, Bayona, Manuel, Fazleabas, Asgerally, Flores, Idhaliz

“…Abstract only Endometriosis defined as the presence of endometrial stroma and glands outside the uterus, is associated with chronic pain, inflammation, and…”
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Validation of Epigenetic Markers in Endometriosis by Colon, Mariano, Colon, Maricarmen, Monteiro, Janice, Baez, Perla, Ruiz, Abigail, Flores, Idhaliz

“…Abstract only Endometriosis is a gynecological disease that affects 1 in 10 women during their reproductive years, cause incapacitating pelvic pain and…”
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Mechanical Response of Mouse Cervices Lacking Decorin and Biglycan During Pregnancy by Lee, Nicole, Shi, Lei, Colon Caraballo, Mariano, Nallasamy, Shanmugasundaram, Mahendroo, Mala, Iozzo, Renato V, Myers, Kristin

“…Cervical remodeling is critical for a healthy pregnancy. The proper regulation of extracellular matrix (ECM) turnover leads to remodeling throughout gestation,…”
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Novel regulatory roles of small leucine-rich proteoglycans in remodeling of the uterine cervix in pregnancy by Colon-Caraballo, Mariano, Lee, Nicole, Nallasamy, Shanmugasundaram, Myers, Kristin, Hudson, David, Iozzo, Renato V., Mahendroo, Mala

“…•Nonpregnant and pregnant compound-null mice deficient in class i (decorin and biglycan) and class II (lumican) SLRPs demonstrate inappropriate assembly of…”
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Decline in corepressor CNOT1 in the pregnant myometrium near term impairs progesterone receptor function and increases contractile gene expression by Kwak, Youn-Tae, Montalbano, Alina P., Kelleher, Andrew M., Colon-Caraballo, Mariano, Kraus, W. Lee, Mahendroo, Mala, Mendelson, Carole R.

“…Progesterone (P4), acting via its nuclear receptor (PR), is critical for pregnancy maintenance by suppressing proinflammatory and contraction-associated…”
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Dissecting the Role of EZH2 and H3K27me3 in Endometriosis by Colon‐Caraballo, Mariano, Soto‐Vargas, John, Urrutia, Raul, Flores, Idhaliz

“…Abstract only Background Endometriosis, defined as the growth and development of endometrial like tissue, ( i.e., glands and stroma) outside the uterine…”
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Effects of psychological stress in histone acetylation (537.2) by Gómez Padilla, Paola, Colón Caraballo, Mariano, Rivera, Ivelisse, Appleyard, Caroline, Flores, Idhaliz

“…Recently, epigenetic factors, including histone modifications, and environmental factors have shown to play an active role in endometriosis. We have recently…”
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