Search Results - "Colon, David F"

IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population by Nascimento, Daniele C., Melo, Paulo H., Piñeros, Annie R., Ferreira, Raphael G., Colón, David F., Donate, Paula B., Castanheira, Fernanda V., Gozzi, Aline, Czaikoski, Paula G., Niedbala, Wanda, Borges, Marcos C., Zamboni, Dario S., Liew, Foo Y., Cunha, Fernando Q., Alves-Filho, Jose C.

“…Patients who survive sepsis can develop long-term immune dysfunction, with expansion of the regulatory T (Treg) cell population. However, how Treg cells…”
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Gasdermin D inhibition prevents multiple organ dysfunction during sepsis by blocking NET formation by Silva, Camila Meirelles S., Wanderley, Carlos Wagner S., Veras, Flavio P., Sonego, Fabiane, Nascimento, Daniele C., Gonçalves, Augusto V., Martins, Timna V., Cólon, David F., Borges, Vanessa F., Brauer, Verônica S., Damasceno, Luis Eduardo A., Silva, Katiussia P., Toller-Kawahisa, Juliana E., Batah, Sabrina S., Souza, Ana Letícia J., Monteiro, Valter S., Oliveira, Antônio Edson R., Donate, Paula B., Zoppi, Daniel, Borges, Marcos C., Almeida, Fausto, Nakaya, Helder I., Fabro, Alexandre T., Cunha, Thiago M., Alves-Filho, José Carlos, Zamboni, Dario S., Cunha, Fernando Q.

“…Multiple organ dysfunction is the most severe outcome of sepsis progression and is highly correlated with a worse prognosis. Excessive neutrophil extracellular…”
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Vestitol Isolated from Brazilian Red Propolis Inhibits Neutrophils Migration in the Inflammatory Process: Elucidation of the Mechanism of Action by Franchin, Marcelo, Cólon, David F, Castanheira, Fernanda V. S, da Cunha, Marcos G, Bueno-Silva, Bruno, Alencar, Severino M, Cunha, Thiago M, Rosalen, Pedro L

“…Vestitol is an isoflavonoid isolated from Brazilian red propolis with potential anti-inflammatory activity. This study investigated the mechanism of action of…”
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Neutrophil Extracellular Traps Effectively Control Acute Chikungunya Virus Infection by Hiroki, Carlos H, Toller-Kawahisa, Juliana E, Fumagalli, Marcilio J, Colon, David F, Figueiredo, Luiz T M, Fonseca, Bendito A L D, Franca, Rafael F O, Cunha, Fernando Q

“…The Chikungunya virus (CHIKV) is a re-emerging arbovirus, in which its infection causes a febrile illness also commonly associated with severe joint pain and…”
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Paediatric sepsis survivors are resistant to sepsis-induced long-term immune dysfunction by Colón, David F, Wanderley, Carlos W, Turato, Walter M, Borges, Vanessa F, Franchin, Marcelo, Castanheira, Fernanda V S, Nascimento, Daniele, Prado, Douglas, Haruo Fernandes de Lima, Mikhael, Volpon, Leila C, Kavaguti, Silvia K, Carlotti, Ana P, Carmona, Fabio, Franklin, Bernardo S, Cunha, Thiago M, Alves-Filho, Jose Carlos, Cunha, Fernando Q

“…Sepsis-surviving adult individuals commonly develop immunosuppression and increased susceptibility to secondary infections, an outcome mediated by the axis…”
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Ilheus and Saint Louis encephalitis viruses elicit cross-protection against a lethal Rocio virus challenge in mice by Amarilla, Alberto Anastacio, Fumagalli, Marcilio Jorge, Figueiredo, Mario Luis, Lima-Junior, Djalma S, Santos-Junior, Nilton Nascimento, Alfonso, Helda Liz, Lippi, Veronica, Trabuco, Amanda Cristina, Lauretti, Flavio, Muller, Vanessa Danielle, Colón, David F, Luiz, João P M, Suhrbier, Andreas, Setoh, Yin Xiang, Khromykh, Alexander A, Figueiredo, Luiz Tadeu Moraes, Aquino, Victor Hugo

“…Rocio virus (ROCV) was the causative agent of an unprecedented outbreak of encephalitis during the 1970s in the Vale do Ribeira, Sao Paulo State, in the…”
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IL-33 signaling is essential to attenuate viral-induced encephalitis development by downregulating iNOS expression in the central nervous system by Franca, Rafael F O, Costa, Renata S, Silva, Jaqueline R, Peres, Raphael S, Mendonça, Leila R, Colón, David F, Alves-Filho, José Carlos, Cunha, Fernando Q

“…Viral encephalitis is a common cause of lethal infections in humans, and several different viruses are documented to be responsible. Rocio virus is a…”
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Paclitaxel Reduces Tumor Growth by Reprogramming Tumor-Associated Macrophages to an M1 Profile in a TLR4-Dependent Manner by Wanderley, Carlos W, Colón, David F, Luiz, João Paulo M, Oliveira, Francisco F, Viacava, Paula R, Leite, Caio A, Pereira, Janaina A, Silva, Camila M, Silva, Cassia R, Silva, Rangel L, Speck-Hernandez, Cesar A, Mota, José M, Alves-Filho, José C, Lima-Junior, Roberto C, Cunha, Thiago M, Cunha, Fernando Q

“…Paclitaxel is an antineoplastic agent widely used to treat several solid tumor types. The primary mechanism of action of paclitaxel is based on microtubule…”
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Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis by Colón, David F, Wanderley, Carlos W, Franchin, Marcelo, Silva, Camila M, Hiroki, Carlos H, Castanheira, Fernanda V S, Donate, Paula B, Lopes, Alexandre H, Volpon, Leila C, Kavaguti, Silvia K, Borges, Vanessa F, Speck-Hernandez, Cesar A, Ramalho, Fernando, Carlotti, Ana P, Carmona, Fabio, Alves-Filho, Jose C, Liew, Foo Y, Cunha, Fernando Q

“…Neutrophil extracellular traps (NETs) are innate defense mechanisms that are also implicated in the pathogenesis of organ dysfunction. However, the role of…”
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Therapeutic potential and limitations of cholinergic anti-inflammatory pathway in sepsis by Kanashiro, Alexandre, Sônego, Fabiane, Ferreira, Raphael G., Castanheira, Fernanda V.S., Leite, Caio A., Borges, Vanessa F., Nascimento, Daniele C., Cólon, David F., Alves-Filho, José Carlos, Ulloa, Luis, Cunha, Fernando Q.

“…[Display omitted] Sepsis is one of the main causes of mortality in hospitalized patients. Despite the recent technical advances and the development of novel…”
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Cinnamoyloxy-mammeisin Isolated from Geopropolis Attenuates Inflammatory Process by Inhibiting Cytokine Production: Involvement of MAPK, AP-1, and NF-κB by Franchin, Marcelo, Rosalen, Pedro Luiz, da Cunha, Marcos Guilherme, Silva, Rangel Leal, Colón, David F, Bassi, Gabriel Shimizu, de Alencar, Severino Matias, Ikegaki, Masaharu, Alves-Filho, José C, Cunha, Fernando Q, Beutler, John A, Cunha, Thiago Mattar

“…Chemical compounds belonging to the class of coumarins have promising anti-inflammatory potential. Cinnamoyloxy-mammeisin (CNM) is a 4-phenylcoumarin that can…”
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Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice by Ramos‐Junior, Erivan S, Leite, Gisele A, Carmo‐Silva, Cecilia C, Taira, Thaise M, Neves, Karla B, Colón, David F, da Silva, Lea AB, Salvador, Sergio L, Tostes, Rita C, Cunha, Fernando Q, Fukada, Sandra Y

“…ABSTRACT Chemerin is an adipokine that regulates adipogenesis and metabolic functions of mature adipocytes mainly through the activation of chemokine‐like…”
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Neovestitol, an isoflavonoid isolated from Brazilian red propolis, reduces acute and chronic inflammation: involvement of nitric oxide and IL-6 by Franchin, Marcelo, Colón, David F., da Cunha, Marcos G., Castanheira, Fernanda V. S., Saraiva, André L. L., Bueno-Silva, Bruno, Alencar, Severino M., Cunha, Thiago M., Rosalen, Pedro L.

“…Isoflavonoids have been largely studied due to their distinct biological activities identified thus far. Herein, we evaluated the activity of neovestitol, an…”
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CCR2 Plays a Protective Role in Rocio Virus-Induced Encephalitis by Promoting Macrophage Infiltration Into the Brain by Amarilla, Alberto A, Santos-Junior, Nilton Nascimento, Figueiredo, Mario Luis, Luiz, Joao Paulo Mesquita, Fumagalli, Marcilio Jorge, Colón, David F, Lippi, Veronica, Alfonso, Helda Liz, Lima-Junior, Djalma S, Trabuco, Amanda C, Spinieli, Richard L, Desidera, Amanda C, Leite-Panissi, Christie R A, Lauretti, Flávio, Mendoza, Silvia Elena Sánchez, Silva, Cleide Lúcia Araújo, Rego, Eduardo Magalhaes, Galvao-Lima, Leonardo J, Bassi, Gabriel S, Penharvel Martíns, Sandra L B, Manrique, Wilson Gomez, Alves-Filho, José Carlos, Cunha, Fernando Q, Peng, Nias Y G, Modhiran, Naphak, Setoh, Yin Xiang, Khromykh, Alexander A, Figueiredo, Luiz T M, Aquino, Victor H

“…Rocio virus (ROCV) is a highly neuropathogenic mosquito-transmitted flavivirus responsible for an unprecedented outbreak of human encephalitis during 1975-1976…”
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