Search Results - "Colombo, Teresa"

PVT1: A Rising Star among Oncogenic Long Noncoding RNAs by Paci, Paola, Macino, Giuseppe, Farina, Lorenzo, Colombo, Teresa

“…It is becoming increasingly clear that short and long noncoding RNAs critically participate in the regulation of cell growth, differentiation, and…”
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Computational analysis identifies a sponge interaction network between long non-coding RNAs and messenger RNAs in human breast cancer by Paci, Paola, Colombo, Teresa, Farina, Lorenzo

“…Non-coding RNAs (ncRNAs) are emerging as key regulators of many cellular processes in both physiological and pathological states. Moreover, the constant…”
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Role of the long non-coding RNA PVT1 in the dysregulation of the ceRNA-ceRNA network in human breast cancer by Conte, Federica, Fiscon, Giulia, Chiara, Matteo, Colombo, Teresa, Farina, Lorenzo, Paci, Paola

“…Recent findings have identified competing endogenous RNAs (ceRNAs) as the drivers in many disease conditions, including cancers. The ceRNAs indirectly regulate…”
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The oncogenic role of circPVT1 in head and neck squamous cell carcinoma is mediated through the mutant p53/YAP/TEAD transcription-competent complex by Verduci, Lorena, Ferraiuolo, Maria, Sacconi, Andrea, Ganci, Federica, Vitale, Jlenia, Colombo, Teresa, Paci, Paola, Strano, Sabrina, Macino, Giuseppe, Rajewsky, Nikolaus, Blandino, Giovanni

“…Circular RNAs are a class of endogenous RNAs with various functions in eukaryotic cells. Worthy of note, circular RNAs play a critical role in cancer…”
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A Census and Categorization Method of Epitranscriptomic Marks by Mathlin, Julia, Le Pera, Loredana, Colombo, Teresa

“…In the past few years, thorough investigation of chemical modifications operated in the cells on ribonucleic acid (RNA) molecules is gaining momentum. This new…”
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RNA-Based Strategies for Cancer Therapy: In Silico Design and Evaluation of ASOs for Targeted Exon Skipping by Pacelli, Chiara, Rossi, Alice, Milella, Michele, Colombo, Teresa, Le Pera, Loredana

“…Precision medicine in oncology has made significant progress in recent years by approving drugs that target specific genetic mutations. However, many cancer…”
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Transcriptional Profiling of Three Pseudomonas syringae pv. actinidiae Biovars Reveals Different Responses to Apoplast-Like Conditions Related to Strain Virulence on the Host by Vandelle, Elodie, Colombo, Teresa, Regaiolo, Alice, Maurizio, Vanessa, Libardi, Tommaso, Puttilli, Maria-Rita, Danzi, Davide, Polverari, Annalisa

“…pv. is a phytopathogen that causes devastating bacterial canker in kiwifruit. Among five biovars defined by genetic, biochemical, and virulence traits, pv…”
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Characterization of epithelial-mesenchymal transition intermediate/hybrid phenotypes associated to resistance to EGFR inhibitors in non-small cell lung cancer cell lines by Fustaino, Valentina, Presutti, Dario, Colombo, Teresa, Cardinali, Beatrice, Papoff, Giuliana, Brandi, Rossella, Bertolazzi, Paola, Felici, Giovanni, Ruberti, Giovina

“…Increasing evidence points to a key role played by epithelial-mesenchymal transition (EMT) in cancer progression and drug resistance. In this study, we used…”
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MicroRNAs Cooperatively Inhibit a Network of Tumor Suppressor Genes to Promote Pancreatic Tumor Growth and Progression by Frampton, Adam E, Castellano, Leandro, Colombo, Teresa, Giovannetti, Elisa, Krell, Jonathan, Jacob, Jimmy, Pellegrino, Loredana, Roca-Alonso, Laura, Funel, Niccola, Gall, Tamara M.H, De Giorgio, Alexander, Pinho, Filipa G, Fulci, Valerio, Britton, David J, Ahmad, Raida, Habib, Nagy A, Coombes, R. Charles, Harding, Victoria, Knösel, Thomas, Stebbing, Justin, Jiao, Long R

“…Background & Aims There has not been a broad analysis of the combined effects of altered activities of microRNAs (miRNAs) in pancreatic ductal adenocarcinoma…”
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AI applications in functional genomics by Caudai, Claudia, Galizia, Antonella, Geraci, Filippo, Le Pera, Loredana, Morea, Veronica, Salerno, Emanuele, Via, Allegra, Colombo, Teresa

“…[Display omitted] We review the current applications of artificial intelligence (AI) in functional genomics. The recent explosion of AI follows the remarkable…”
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Growth arrest-specific transcript 5 associated snoRNA levels are related to p53 expression and DNA damage in colorectal cancer by Krell, Jonathan, Frampton, Adam E, Mirnezami, Reza, Harding, Victoria, De Giorgio, Alex, Roca Alonso, Laura, Cohen, Patrizia, Ottaviani, Silvia, Colombo, Teresa, Jacob, Jimmy, Pellegrino, Loredana, Buchanan, Gordon, Stebbing, Justin, Castellano, Leandro

“…The growth arrest-specific transcript 5 gene (GAS5) encodes a long noncoding RNA (lncRNA) and hosts a number of small nucleolar RNAs (snoRNAs) that have…”
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Interleukin-8 in Colorectal Cancer: A Systematic Review and Meta-Analysis of Its Potential Role as a Prognostic Biomarker by Bazzichetto, Chiara, Milella, Michele, Zampiva, Ilaria, Simionato, Francesca, Amoreo, Carla Azzurra, Buglioni, Simonetta, Pacelli, Chiara, Le Pera, Loredana, Colombo, Teresa, Bria, Emilio, Zeuli, Massimo, Del Bufalo, Donatella, Sperduti, Isabella, Conciatori, Fabiana

“…Among soluble actors that have emerged as druggable factors, the chemokine interleukin-8 (IL-8) has emerged as a possible determinant of response to…”
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Large-scale sorting of C. elegans embryos reveals the dynamics of small RNA expression by Piano, Fabio, Rajewsky, Nikolaus, Stoeckius, Marlon, Maaskola, Jonas, Colombo, Teresa, Rahn, Hans-Peter, Friedländer, Marc R, Li, Na, Chen, Wei

“…Fluorescence-activated cell sorting of worm embryos promises to replace manual sorting of staged embryos and yields large populations highly enriched in…”
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Plant and fungus transcriptomic data from grapevine berries undergoing artificially-induced noble rot caused by Botrytis cinerea by Lovato, Arianna, Zenoni, Sara, Tornielli, Giovanni Battista, Colombo, Teresa, Vandelle, Elodie, Polverari, Annalisa

“…Noble rot is a latent infection of grape berries caused by the necrotrophic fungus Botrytis cinerea, which develops under specific climatic conditions. The…”
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The role of TP53 in miRNA loading onto AGO2 and in remodelling the miRNA–mRNA interaction network by Krell, Jonathan, Dr, Stebbing, Justin, PhD, Frampton, Adam Enver, PhD, Carissimi, Claudia, PhD, Harding, Victoria, MRCP, De Giorgio, Alexander, MA, Fulci, Valerio, PhD, Macino, Giuseppe, PhD, Colombo, Teresa, PhD, Castellano, Leandro, PhD

“…Abstract Background DNA damage transactivates tumour protein p53 (TP53) -regulated surveillance, crucial in suppressing tumorigenesis. TP53 mediates this…”
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The p53 miRNA interactome and its potential role in the cancer clinic by Krell, Jonathan, Frampton, Adam E, Colombo, Teresa, Gall, Tamara M H, De Giorgio, Alex, Harding, Victoria, Stebbing, Justin, Castellano, Leandro

“…p53 is one of the most frequently mutated tumor suppressors. It regulates protein-coding genes and noncoding RNAs involved in many cellular processes,…”
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Integrated molecular analysis to investigate the role of microRNAs in pancreatic tumour growth and progression by Frampton, Adam E, Dr, Castellano, Leandro, PhD, Colombo, Teresa, PhD, Giovannetti, Elisa, PhD, Krell, Jonathan, PhD, Jacob, Jimmy, PhD, Pellegrino, Loredana, PhD, Roca-Alonso, Laura, PhD, Funel, Niccola, PhD, Gall, Tamara M H, MRCS, Ahmad, Raida, FRCPath, Habib, Nagy A, FRCS, Knösel, Thomas, PhD, Stebbing, Justin, PhD, Jiao, Long R, FRCS

“…Abstract Background MicroRNAs (miRNAs) are small non-coding RNAs involved in the post-transcriptional regulation of mRNAs and are aberrantly expressed in…”
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Comprehensive RNA dataset of AGO2 associated RNAs in Jurkat cells following miR-21 over-expression by Carissimi, Claudia, Colombo, Teresa, Azzalin, Gianluca, Cipolletta, Emanuela, Laudadio, Ilaria, Macino, Giuseppe, Fulci, Valerio

“…We set out to identify miR-21 targets in Jurkat cells using a high-throughput biochemical approach (10.1016/j.biochi.2014.09.021[1]). Using a specific…”
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SWIM: a computational tool to unveiling crucial nodes in complex biological networks by Paci, Paola, Colombo, Teresa, Fiscon, Giulia, Gurtner, Aymone, Pavesi, Giulio, Farina, Lorenzo

“…SWItchMiner (SWIM) is a wizard-like software implementation of a procedure, previously described, able to extract information contained in complex networks…”
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Inverse Problems in Systems Biology: A Critical Review by Guzzi, Rodolfo, Colombo, Teresa, Paci, Paola

“…Systems Biology may be assimilated to a symbiotic cyclic interplaying between the forward and inverse problems. Computational models need to be continuously…”
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