Search Results - "Colombo, Sergio L."
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Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells
Published in Proceedings of the National Academy of Sciences - PNAS (27-12-2011)“…During cell division, the activation of glycolysis is tightly regulated by the action of two ubiquitin ligases, anaphase-promoting complex/cyclosome–Cdh1…”
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Fulfilling the metabolic requirements for cell proliferation
Published in Biochemical journal (15-08-2012)“…The activity of key metabolic enzymes is regulated by the ubiquitin ligases that control the function of the cyclins; therefore the activity of these ubiquitin…”
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Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-β-TrCP, sequentially regulate glycolysis during the cell cycle
Published in Proceedings of the National Academy of Sciences - PNAS (29-03-2011)“…During cell proliferation, the abundance of the glycolysis-promoting enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, isoform 3 (PFKFB3), is…”
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4
Mitochondria as Signaling Organelles in the Vascular Endothelium
Published in Proceedings of the National Academy of Sciences - PNAS (04-04-2006)“…Vascular endothelial cells are highly glycolytic and consume relatively low amounts of oxygen (O₂) compared with other cells. We have confirmed that oxidative…”
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Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes
Published in Proceedings of the National Academy of Sciences - PNAS (02-11-2010)“…Cell proliferation is accompanied by an increase in the utilization of glucose and glutamine. The proliferative response is dependent on a decrease in the…”
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Increased IL-2 and Reduced TGF-β Upon T-Cell Stimulation are Associated with GM-CSF Upregulation in Multiple Immune Cell Types in Multiple Sclerosis
Published in Biomedicines (18-07-2020)“…Granulocyte macrophage colony stimulating factor (GM-CSF) is a pro-inflammatory cytokine produced by immune cells. Recent evidence suggests that GM-CSF plays…”
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Rubisco activase is required for optimal photosynthesis in the green alga Chlamydomonas reinhardtii in a low-Co2 atmosphere
Published in Plant physiology (Bethesda) (01-12-2003)“…This report describes a Chlamydomonas reinhardtii mutant that lacks Rubisco activase (Rca). Using the BleR (bleomycin resistance) gene as a positive selectable…”
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Carnosine protects stimulus-secretion coupling through prevention of protein carbonyl adduction events in cells under metabolic stress
Published in Free radical biology & medicine (01-11-2021)“…Type 2 diabetes is characterised by failure to control glucose homeostasis, with numerous diabetic complications attributable to the resulting exposure of…”
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Rubisco Activase Is Required for Optimal Photosynthesis in the Green Alga Chlamydomonas reinhardtii in a Low-CO2 Atmosphere1
Published in Plant physiology (Bethesda) (01-12-2003)“…This report describes a Chlamydomonas reinhardtii mutant that lacks Rubisco activase (Rca). Using the BleR (bleomycin resistance) gene as a positive selectable…”
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Properties of DNA polymerase from petunia "mitchell" chloroplasts: Inhibitory effects of flavonoids
Published in Bioscience, biotechnology, and biochemistry (01-01-1994)“…A DNA polymerase has been assayed from chloroplasts of petunia plants cultured in vitro. The enzyme activity depends on the presence of DNA and Mg(2+) and is…”
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Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-[Beta]-TrCP, sequentially regulate glycolysis during the cell cycle
Published in Proceedings of the National Academy of Sciences - PNAS (29-03-2011)“…During cell proliferation, the abundance of the glycolysis-promoting enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, isoform 3 (PFKFB3), is…”
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12
Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-β-TrCP, sequentially regulate glycolysis during the cell cycle
Published in Proceedings of the National Academy of Sciences - PNAS (2011)“…During cell proliferation, the abundance of the glycolysis-promoting enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, isoform 3 (PFKFB3), is…”
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13
AMPKalpha1 regulates the antioxidant status of vascular endothelial cells
Published in Biochemical journal (26-06-2009)“…AMPK (AMP-activated protein kinase) is a key regulator of cellular energy because of its capacity to detect changes in the concentration of AMP. Recent…”
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14
Rubisco activase is required for optimal photosynthesis in the green alga Chlamydomonas reinhardtii in a low-CO(2) atmosphere
Published in Plant physiology (Bethesda) (01-12-2003)“…This report describes a Chlamydomonas reinhardtii mutant that lacks Rubisco activase (Rca). Using the BleR (bleomycin resistance) gene as a positive selectable…”
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15
The interaction of shikimic acid and protein phosphorylation with pep carboxylase from the C 4 dicot Amaranthus viridis
Published in Phytochemistry (Oxford) (01-05-1998)“…The effect of shikimic acid was studied on the purified dephospho and phosphorylated (in vitro) forms of PEPC from Amaranthus viridis. Kinetic analysis showed…”
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The interaction of shikimic acid and protein phosphorylation with PEP carboxylase from the C4 dicot Amaranthus viridis
Published in Phytochemistry (Oxford) (01-05-1998)“…Shikimic acid has been described as a potent competitive inhibitor of the activity of C4 phosphoenolpyruvate carboxylase (PEPC) from Amaranthus viridis. In the…”
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Flavonoids as Inhibitors of NADP-Malic Enzyme and PEP Carboxylase from C 4 Plants
Published in Bioscience, biotechnology, and biochemistry (01-05-1996)Get full text
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Inhibitory Effect of Shikimic Acid on PEP Carboxylase Activity
Published in Plant and cell physiology (01-09-1996)“…The inhibitory effect of shikimic acid on phosphoenolpyruvate carboxylase (PEPC) from Amaranthus leaves was evaluated. Shikimic acid behaved as a competitive…”
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Flavonoids as Inhibitors of NADP-Malic Enzyme and PEP Carboxylase from C4 Plants
Published in Bioscience, biotechnology, and biochemistry (1996)“…The inhibitory effects of flavonoids on the activity of two photosynthetic enzymes such as phosphoenol- pyruvate carboxylase (PEPCase) and NADP-dependent malic…”
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Interaction of analogues of substrate with NADP-malic enzyme from maize leaves
Published in Photosynthesis research (01-01-1994)“…The effect of structural analogues of L-malate was studied on NADP-malic enzyme purified from Zea mays L. leaves. Among the compounds tested, the organic acids…”
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