Effects of acute exposure to altitude (3,460 m) on blood pressure response to dynamic and isometric exercise in men with systemic hypertension

The effects of the acute exposure to altitude on the cardiovascular system have been extensively studied. 1–4 In normal subjects, reports on blood pressure (BP) changes associated with initial exposure to altitude lack general agreement: some investigators have found a small increase, 5,6 others a s...

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Bibliographic Details
Published in:	The American journal of cardiology Vol. 70; no. 18; pp. 1493 - 1497
Main Authors:	Savonitto, Stefano, Cardellino, Giovanni, Doveri, Giulio, Pernpruner, Silvia, Bronzini, Roberto, Milloz, Nicole, Colombo, M.Delia, Sardina, Marco, Nassi, Guido, Marraccini, Paolo
Format:	Journal Article
Language:	English
Published:	New York, NY Elsevier Inc 01-12-1992 Elsevier
Subjects:	Adult Aged Altitude Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Blood Pressure - physiology Cardiology. Vascular system Clinical manifestations. Epidemiology. Investigative techniques. Etiology Diastole - physiology Electrocardiography Exercise - physiology Exercise Test Heart Rate - physiology Humans Hypertension - physiopathology Male Medical sciences Middle Aged Physical Exertion - physiology Space life sciences Systole - physiology Human Hypertension Heart rate Bicycle ergometer Cardiovascular disease Isometric muscular contraction Exercise tolerance test Exploration Blood pressure Altitude
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Summary:	The effects of the acute exposure to altitude on the cardiovascular system have been extensively studied. 1–4 In normal subjects, reports on blood pressure (BP) changes associated with initial exposure to altitude lack general agreement: some investigators have found a small increase, 5,6 others a small reduction 7,8 and others no change. 9–11 Two articles have recently reported BP reactivity at altitude in patients with systemic arterial hypertension, showing that the exposure to an altitude between 2,500 and 3,000 m induces a small increase in systolic BP 6 or no change at all. 12 Neither study investigated the BP response to exercise during acute exposure to altitude. The subject is of practical relevance since many uncomplicated hypertensive subjects are discouraged from hiking or skiing at altitudes for fear that acute hypoxia may produce excessive hypertension. In this study we investigated the effects of an acute change in altitude of 2,090 m on BP and heart rate responsiveness to dynamic and isometric exercise in untreated hypertensive patients.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0002-9149 1879-1913
DOI:	10.1016/0002-9149(92)90308-L