Search Results - "Colombo, John S"

Scaffolds to Control Inflammation and Facilitate Dental Pulp Regeneration by Colombo, John S., PhD, Moore, Amanda N., BS, Hartgerink, Jeffrey D., PhD, D’Souza, Rena N., DDS, PhD

“…Abstract In dentistry, the maintenance of a vital dental pulp is of paramount importance because teeth devitalized by root canal treatment may become more…”
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Sequence Effects of Self-Assembling MultiDomain Peptide Hydrogels on Encapsulated SHED Cells by Kang, Marci K, Colombo, John S, D’Souza, Rena N, Hartgerink, Jeffrey D

“…Here we report three new nanofibrous, self-assembling multidomain peptide (MDP) sequences and examine the effect of sequence on the morphology and expansion of…”
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Dental Pulp Stem Cell Heterogeneity: Finding Superior Quality “Needles” in a Dental Pulpal “Haystack” for Regenerative Medicine-Based Applications by Kok, Zi Y., Alaidaroos, Nadia Y. A., Alraies, Amr, Colombo, John S., Davies, Lindsay C., Waddington, Rachel J., Sloan, Alastair J., Moseley, Ryan

“…Human dental pulp stem/stromal cells (hDPSCs) derived from the permanent secondary dentition are recognised to possess certain advantageous traits, which…”
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Elucidating the cellular actions of demineralised dentine matrix extract on a clonal dental pulp stem cell population in orchestrating dental tissue repair by Lee, Chi P, Colombo, John S, Ayre, Wayne Nishio, Sloan, Alastair J, Waddington, Rachel J

“…Bioactive growth factors identified within the extracellular matrix of dentine have been proposed roles in regulating the naturally inherent regenerative…”
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Modeling Hypoxia Induced Factors to Treat Pulpal Inflammation and Drive Regeneration by Colombo, John S., Jia, Shihai, D'Souza, Rena N.

“…Introduction: The ability to resolve pulpal inflammation to achieve predictable regeneration of the dentin-pulp complex has remained elusive and presents a…”
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Characterization of oxidative stress status during diabetic bone healing by Waddington, Rachel J, Alraies, Amr, Colombo, John S, Sloan, Alastair J, Okazaki, Joji, Moseley, Ryan

“…Early events associated with bone healing in patients with type 2 diabetes mellitus appear to be delayed. Hyperglycaemia and an associated increase in…”
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Highly targeted electrochemical disruption of microbes with minimal disruption to pulp cells by Colombo, John S., Malik, Hammad, Caranto, Christian Ariana, Allen, Patrina K., Howard, Jerry, Carlson, Krista

“…Pulpitis results from the infiltration of mixed populations of bacteria which trigger inflammation in the dental pulp, causing significant disruption to these…”
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Liposomal Delivery of Demineralized Dentin Matrix for Dental Tissue Regeneration by Melling, Genevieve E, Colombo, John S, Avery, Steven J, Ayre, Wayne Nishio, Evans, Samuel L, Waddington, Rachel J, Sloan, Alastair J

“…Current dental restorations have short longevity, and consequently, there is a need for novel tissue engineering strategies that aim to regenerate the…”
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Synthesis and characterization of novel calcium phosphate glass-derived cements for vital pulp therapy by Howard, Jerry, Gardner, Levi, Saifee, Zahra, Geleil, Aladdin, Nelson, Isaac, Colombo, John S., Naleway, Steven E., Carlson, Krista

“…Evaluation of the physicochemical behavior and setting reactions of a novel inorganic pulp capping cement which makes use of the unique corrosion properties of…”
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How Research Training Will Shape the Future of Dental, Oral, and Craniofacial Research by D'souza, Rena N., Colombo, John S.

“…This is a critical time in the history of the dental profession for it to fully embrace the responsibility to safeguard its reputation as a learned profession…”
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Innovative Molecular and Cellular Therapeutics in Cleft Palate Tissue Engineering by Oliver, Jeremie D, Jia, Shihai, Halpern, Leslie R, Graham, Emily M, Turner, Emma C, Colombo, John S, Grainger, David W, D'Souza, Rena N

“…Clefts of the lip and/or palate are the most prevalent orofacial birth defects occurring in about 1:700 live human births worldwide. Early postnatal surgical…”
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Epidermal growth factor receptor genes are overexpressed within the periprosthetic soft‐tissue around percutaneous devices: A pilot study by Jeyapalina, Sujee, Colombo, John S., Beck, James P., Agarwal, Jayant P., Schmidt, Linda A., Bachus, Kent N.

“…Epidermal downgrowth around percutaneous devices produce sinus tracts, which then accumulate bacteria becoming foci of infection. This mode to failure is…”
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Delayed osteoblast differentiation and altered inflammatory response around implants placed in incisor sockets of type 2 diabetic rats by Colombo, John S., Balani, Deepak, Sloan, Alastair J., Crean, St John, Okazaki, Joji, Waddington, Rachel J.

“…Objective: Central to the process of osseointegration is the recruitment of mesenchymal progenitor cells to the healing site, their proliferation and…”
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A Single-Step Self-Assembly Approach for the Fabrication of Aligned and Multilayered Three-Dimensional Tissue Constructs Using Multidomain Peptide Hydrogel by Wee, Yinshen, Moore, Amanda N, Jia, Shihai, Zhou, Jing, Colombo, John S, D'Souza, Rena N

“…Hydrogels are homogenous materials that are limited in their ability to form oriented multilayered architecture in three-dimensional (3D) tissue constructs…”
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In vivo monitoring of the bone healing process around different titanium alloy implant surfaces placed into fresh extraction sockets by Colombo, John S, Satoshi, Sanda, Okazaki, Joji, Crean, StJohn, Sloan, Alastair J, Waddington, Rachel J

“…Abstract Objectives Increasing surface roughness and coating with tricalcium phosphate of titanium and titanium alloy implants has been proposed to provide…”
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Osteogenic potential of bone marrow stromal cells on smooth, roughened, and tricalcium phosphate-modified titanium alloy surfaces by Colombo, John S, Carley, Albert, Fleming, Garry J P, Crean, St John, Sloan, Alastair J, Waddington, Rachel J

“…This study investigated the influence of smooth, roughened, and tricalcium phosphate (TCP)-coated roughened titanium-aluminum-vanadium (Ti-6Al-4V) surfaces on…”
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A 3D ex vivo mandible slice system for longitudinal culturing of transplanted dental pulp progenitor cells by Colombo, John S., Howard‐Jones, Rachel A., Young, Fraser I., Waddington, Rachel J., Errington, Rachel J., Sloan, Alastair J.

“…Harnessing mesenchymal stem cells for tissue repair underpins regenerative medicine. However, how the 3D tissue matrix maintains such cells in a quiescent…”
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Differential cellular and microbial responses to nano-/micron-scale titanium surface roughness induced by hydrogen peroxide treatment by Daw, Abdulaziz E, Kazi, Hizbullah AA, Colombo, John S, Rowe, Wendy G, Williams, David W, Waddington, Rachel J, Thomas, David W, Moseley, Ryan

“…This study investigated the effects of combined titanium nano-/micron-scale roughness, induced by hydrogen peroxide pre-treatments, on bone marrow stromal cell…”
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Delayed osteoblast differentiation and altered inflammatory response around implants placed in incisor sockets of type 2 diabetic rats by Colombo, John S., Balani, Deepak, Sloan, Alastair J., Crean, St John, Okazaki, Joji, Waddington, Rachel J.

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Characterization and evaluation of fluoridated apatites for the development of infection-free percutaneous devices by Bennett, Brian T., Beck, James Peter, Papangkorn, Kongnara, Colombo, John S., Bachus, Kent N., Agarwal, Jayant, Shieh, Joshua F., Jeyapalina, Sujee

“…The wound healing process in the soft tissues adjacent to percutaneous implants induces “epithelial downgrowth”, and subsequently, a sinus tract around the…”
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