Search Results - "Colombo, Fabio Antônio"
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Anti-Toxoplasma gondii screening of MMV pandemic response box and evaluation of RWJ-67657 efficacy in chronically infected mice
Published in Parasitology (01-11-2023)“…Toxoplasmosis is a significant public health concern with limited therapeutic options. The medicines for malaria venture (MMV) developed the pandemic response…”
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Synthesis and evaluation of the antileishmanial activity of silver compounds containing imidazolidine-2-thione
Published in Journal of biological inorganic chemistry (01-05-2019)“…A new series of silver compounds could be of interest on designing new drugs for the treatment of leishmaniasis. The compounds [Ag(phen)(imzt)]NO 3 (1) ,…”
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Repurposing the Medicines for Malaria Venture's COVID Box to discover potent inhibitors of Toxoplasma gondii, and in vivo efficacy evaluation of almitrine bismesylate (MMV1804175) in chronically infected mice
Published in PloS one (07-07-2023)“…Toxoplasmosis, caused by the obligate intracellular parasite Toxoplasma gondii, affects about one-third of the world's population and can cause severe…”
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4
Camu-camu (Myrciaria dubia) seeds as a novel source of bioactive compounds with promising antimalarial and antischistosomicidal properties
Published in Food research international (01-10-2020)“…[Display omitted] •Camu-camu seed extracts presented antimalarial and antischistosomicidal activities.•Methylvescalagin was the bioactive compound correlated…”
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Assessment of nebivolol efficacy in experimental models of toxoplasmosis: insights into parasite burden reduction and neuronal protection
Published in Parasitology research (1987) (20-08-2024)“…This study investigates the efficacy of nebivolol (NBV) in experimental models of toxoplasmosis, focusing on parasite burden reduction and neuronal protection…”
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Case Report: Human Bertiellosis in Brazil
Published in The American journal of tropical medicine and hygiene (01-01-2023)“…The Anoplocephalidae family comprises a group of parasites that affect reptiles, birds, and mammals. Humans can be accidentally infected by ingesting…”
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Radiographic and antimicrobial evaluation of enterococcus Faecalis and Actinomyces Israelii micro-organisms after photodynamic therapy (aPDT)
Published in Photodiagnosis and photodynamic therapy (01-09-2021)“…•aPDT did not prove superior to conventional techniques.•The group with aPDT application was similar to the group without aPDT.•More studies are needed to…”
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In vivo evaluation of anti-Leishmania activity of alkyltriazoles and alkylphosphocholines by oral route
Published in Experimental parasitology (01-07-2021)“…The failures in the treatment of leishmaniasis is an increasing problem around the world, especially related to resistance. Thus, we describe the synthesis and…”
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Investigation of 8-methoxy-3-(4-nitrobenzoyl)-6-propyl-2H-chromen-2-one as a promising coumarin compound for the development of a new and orally effective antileishmanial agent
Published in Molecular biology reports (01-11-2020)“…Changes in host immunity and parasite resistance to drugs are among the factors that contribute to decreased efficacy of antiparasitic drugs such as the…”
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First Description of Marinoquinoline Derivatives' Activity against Toxoplasma gondii
Published in Pharmaceutics (10-02-2024)“…Toxoplasmosis is a globally prevalent zoonotic disease with significant clinical implications, including neurotoxoplasmosis, a leading cause of cerebral…”
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11
Comparative analysis of real-time PCR assays in the detection of canine visceral leishmaniasis
Published in Parasitology research (1987) (01-10-2018)“…Dogs are important hosts and reservoirs of leishmaniasis, a disease caused by protozoan parasites from the genus Leishmania, affecting ~12 million people…”
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Effect of EDTA on TGF-β1 released from the dentin matrix and its influence on dental pulp stem cell migration
Published in Brazilian oral research (2016)“…Bioactive molecules stored in dentin, such as transforming growth factor beta1 (TGF-b1), may be involved in the signaling events related to dental tissue…”
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First detection of Leishmania spp. DNA in Brazilian bats captured strictly in urban areas
Published in Acta tropica (01-10-2015)“…[Display omitted] •We analyzed 488 bats captured in urban area for the presence of Leishmania ssp. kDNA.•The 23.9% of bats were positive for the presence of…”
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Leishmania infantum INFECTION IN DOGS FROM THE SOUTHERN REGION OF MINAS GERAIS STATE, BRAZIL
Published in Revista do Instituto de Medicina Tropical de São Paulo (01-01-2016)“…Visceral leishmaniasis is a systemic and chronic disease and dogs are the main reservoir of the etiologic agent, Leishmania infantum (syn L. chagasi). A…”
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PCR Assay Using Cerebrospinal Fluid for Diagnosis of Cerebral Toxoplasmosis in Brazilian AIDS patients
Published in Journal of Clinical Microbiology (01-10-2004)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Importance of high IgG anti-Toxoplasma gondii titers and PCR detection of T. gondii DNA in peripheral blood samples for the diagnosis of AIDS-related cerebral toxoplasmosis: a case-control study
Published in The Brazilian journal of infectious diseases (01-07-2011)“…Cerebral toxoplasmosis (CT) continues to cause significant morbidity and mortality in human immunodeficiency virus (HIV)-infected patients in Brazil. In…”
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Importance of high IgG anti-Toxoplasma gondii titers and PCR detection of T. gondii DNA in peripheral blood samples for the diagnosis of AIDS-related cerebral toxoplasmosis: a case-control study
Published in The Brazilian journal of infectious diseases (01-08-2011)“…BACKGROUND: Cerebral toxoplasmosis (CT) continues to cause significant morbidity and mortality in human immunodeficiency virus (HIV)-infected patients in…”
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Repurposing the Medicines for Malaria Venture's COVID Box to discover potent inhibitors of Toxoplasma gondii, and in vivo efficacy evaluation of almitrine bismesylate
Published in PloS one (07-07-2023)“…Toxoplasmosis, caused by the obligate intracellular parasite Toxoplasma gondii, affects about one-third of the world's population and can cause severe…”
Get full text
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19
First Description of Marinoquinoline Derivatives’ Activity against IToxoplasma gondii/I
Published in Pharmaceutics (01-02-2024)“…Toxoplasmosis is a globally prevalent zoonotic disease with significant clinical implications, including neurotoxoplasmosis, a leading cause of cerebral…”
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20
Performance of a real time PCR for leishmaniasis diagnosis using a L. (L.) infantum hypothetical protein as target in canine samples
Published in Experimental parasitology (01-10-2015)“…Visceral leishmaniasis represents an important public health issue in different parts of the world, requiring that measures be put in place to control the…”
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