Search Results - "Colnaghi, Maria I."

Response to Cyclophosphamide, Methotrexate, and Fluorouracil in Lymph Node–Positive Breast Cancer According to HER2 Overexpression and Other Tumor Biologic Variables by MENARD, Sylvie, VALAGUSSA, Pinuccia, CASCINELLI, Natale, BONADONNA, Gianni, PILOTTI, Silvana, GIANNI, Luca, BIGANZOLI, Elia, BORACCHI, Patrizia, TOMASIC, Gorand, CASALINI, Patrizia, MARUBINI, Ettore, COLNAGHI, Maria I

“…There is considerable interest in biologic markers able to predict the response of cancer patients to therapy. HER2 overexpression is a potential indicator of…”
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A comparative study of p53 gene mutations, protein accumulation, and response to cisplatin-based chemotherapy, in advanced ovarian carcinoma by RIGHETTI, S. C, DELLA TORRE, G, BÖHM, S, BRESCIANI, G. L, SPATTI, G, ZUNINO, F, PILOTTI, S, MENARD, S, OTTONE, F, COLNAGHI, M. L, PIEROTTI, M. A, LAVARINO, C, CORNAROTTI, M, ORIANA, S

“…The p53 protein is a multifunctional transcriptional regulator involved in cellular response to DNA damage and has been implicated as a putative determinant of…”
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Panning phage antibody libraries on cells : Isolation of human Fab fragments against ovarian carcinoma using guided selection by FIGINI, M, OBICI, L, MEZZANZANICA, D, GRIFFITHS, A, COLNAGHI, M. I, WINTER, G, CANEVARI, S

“…The display of repertoires of human antibody (Ab) fragments on filamentous phages and selection by binding of the phage to antigen (Ag) have provided a ready…”
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Formation of the 67-kDa laminin receptor by acylation of the precursor by Butò, Simona, Tagliabue, Elda, Ardini, Elena, Magnifico, Alessandra, Ghirelli, Cristina, van den Brûle, Frédéric, Castronovo, Vincent, Colnaghi, Maria I., Sobel, Mark E., Ménard, Sylvie

“…Even though the involvement of the 67‐kDa laminin receptor (67LR) in tumor invasiveness has been clearly demonstrated, its molecular structure remains an open…”
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Tamoxifen chemoprevention of a hormone-independent tumor in the proto-neu transgenic mice model by MENARD, S, AIELLO, P, TAGLIABUE, E, RUMIO, C, LOLLINI, P. L, COLNAGHI, M. I, BALSARI, A

“…We evaluated the effect of tamoxifen (TAM) on tumor development in proto-neu transgenic mice that spontaneously develop mammary carcinomas overexpressing the…”
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Tumor Pretargeting: Role of Avidin/Streptavidin on Monoclonal Antibody Internalization by Casalini, Patrizia, Luison, Elena, Menard, Sylvie, Colnaghi, Maria I, Paganelli, Giovanni, Canevari, Silvana

“…Radioimmunodetection of tumor can be improved by introducing a two-step system in which radiolabeled streptavidin is administrated after the injection of a…”
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Oral administration of anti-doxorubicin monoclonal antibody prevents chemotherapy-induced gastrointestinal toxicity in mice by MORELLI, D, MENARD, S, COLNAGHI, M. I, BALSARI, A

“…Gastrointestinal mucositis is a common and painful condition that afflicts a proportion of cancer patients receiving chemotherapeutic drugs including…”
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Gene transfection and expression of the ovarian carcinoma marker folate binding protein on NIH/3T3 cells increases cell growth in vitro and in vivo by BOTTERO, F, TOMASSETTI, A, CANEVARI, S, MIOTTI, S, MENARD, S, COLNAGHI, M. I

“…The glycoprotein gp38 is overexpressed in 90% of ovarian carcinomas and recognized by monoclonal antibodies MOv18 and MOv19. This molecule is a high affinity…”
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Antibody response against the c-erbB-2 oncoprotein in breast carcinoma patients by PUPA, S. M, MENARD, S, ANDREOLA, S, COLNAGHI, M. I

“…Indirect immunofluorescence analysis of sera from breast carcinoma patients whose tumors were characterized for overexpression of the c-erbB-2 oncoprotein…”
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CD3-CD28 costimulation as a means to avoiding T cell preactivation in bispecific monoclonal antibody-based treatment of ovarian carcinoma by MAZZONI, A, MEZZANZANICA, D, JUNG, G, WOLF, H, COLNAGHI, M. I, CANEVARI, S

“…One of the major limitations to the immunotherapy of ovarian carcinoma based on the use of anti-CD3/antitumor bispecific monoclonal antibodies (bi-mAb) is the…”
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Peptide G, Containing the Binding Site of the 67-kDa Laminin Receptor, Increases and Stabilizes Laminin Binding to Cancer Cells by Magnifico, Alessandra, Tagliabue, Elda, Butó, Simona, Ardini, Elena, Castronovo, Vincent, Colnaghi, Maria I., Ménard, Sylvie

“…We investigated the effect of peptide G, a synthetic peptide derived from the sequence of the 37-kDa laminin receptor precursor, on the interaction of laminin…”
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Local Concentration of Folate Binding Protein GP38 in Sections of Human Ovarian Carcinoma by In Vitro Quantitative Autoradiography by Li, Pei Yong, Del Vecchio, Silvana, Fonti, Rosa, Carriero, Maria V, Potena, Maria I, Botti, Gerardo, Miotti, Silvia, Lastoria, Secondo, Menard, Sylvie, Colnaghi, Maria I, Salvatore, Marco

“…Folate binding protein (FBP) GP38 is a membrane-associated glycoprotein that mediates the intracellular transport of folates. The enhanced expression of FBP in…”
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Cooperative effects of Mycobacterium tuberculosis Ag38 gene transduction and interleukin 12 in vaccination against spontaneous tumor development in proto-neu transgenic mice by SFONDRINI, L, RODOLFO, M, SINGH, M, COLOMBO, M. P, COLNAGHI, M. I, MENARD, S, BALSARI, A

“…An approach to stimulating an immune response against tumors is to transduce tumor cells with bacterial genes, which represent a "danger signal" and can induce…”
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Protection against doxorubicin-induced alopecia in rats by liposome-entrapped monoclonal antibodies by Balsari, A L, Morelli, D, Ménard, S, Veronesi, U, Colnaghi, M I

“…Alopecia is a common side effect of several anti-cancer drugs, including doxorubicin. Based on our recent observation that a monoclonal antibody (MAD11)…”
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Ectopic expression of pRb2/p130 suppresses the tumorigenicity of the c-erbB-2-overexpressing SKOV3 tumor cell line by PUPA, S. M, HOWARD, C. M, INVERNIZZI, A. M, DE VECCHI, R, GIANI, C, CLAUDIO, P. P, COLNAGHI, M. I, GIORDANO, A, MENARD, S

“…We investigated the in vitro and in vivo effects of the ectopic expression of the pRb2/p130 cell cycle regulator on c-erbB-2-associated tumorigenicity. SKOV3…”
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Role of Cross-Linking Agents in Determining the Biochemical and Pharmacokinetic Properties of Mgr6−Clavin Immunotoxins by Dosio, Franco, Arpicco, Silvia, Adobati, Elena, Canevari, Silvana, Brusa, Paola, De Santis, Rita, Parente, Dino, Pignanelli, Paola, Negri, Donatella R. M, Colnaghi, Maria I, Cattel, Luigi

“…Several immunotoxins (ITs) were synthesized by the attachment of clavin, a recombinant toxic protein derived from Aspergillus clavatus, to the monoclonal…”
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Generation of monoclonal antibodies reacting with normal and cancer cells of human breast by Mènard, S, Tagliabue, E, Canevari, S, Fossati, G, Colnaghi, M I

“…From the fusion of the murine myeloma P3- X63-Ag8-U1 with spleen cells from a mouse immunized with the human breast cancer cell line MCF-7, 88 hybridomas…”
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Anti-tumor efficacy of an anti-epidermal-growth-factor-receptor monoclonal antibody and its F(ab')2 fragment against high- and low-EGFR-expressing carcinomas in nude mice by Tosi, E, Valota, O, Negri, D R, Adobati, E, Mazzoni, A, Meazza, R, Ferrini, S, Colnaghi, M I, Canevari, S

“…Monoclonal antibody (MAb) MINT5 specifically detects the epidermal-growth-factor receptor (EGFR). In vitro analyses of intact MINT5 (IgG1) and its F(ab')2…”
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Tumor-necrosis-factor-induced fibroblast growth factor-1 acts as a survival factor in a transformed endothelial cell line by Maier, JA, Morelli, D, Menard, S, Colnaghi, MI, Balsari, A

“…Endothelial cells undergo apoptosis after withdrawal of growth factors, alterations in the extracellular matrix, or exposure to cytokines. Here we report that…”
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Approaches to implement bispecific antibody treatment of ovarian carcinoma by CANEVARI, S, MEZZANZANICA, D, MAZZONI, A, NEGRI, D. R. M, FIGINI, M, RAMAKRISHNA, V, BOLIS, G, COLNAGHI, M. I

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