Search Results - "Colloc’h, N"
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Arginine 260 of the Amino-terminal Domain of NR1 Subunit Is Critical for Tissue-type Plasminogen Activator-mediated Enhancement of N-Methyl-D-aspartate Receptor Signaling
Published in The Journal of biological chemistry (03-12-2004)“…Tissue-type plasminogen activator (tPA) has been involved in both physiological and pathological glutamatergic-dependent processes, such as synaptic…”
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Interactions in solution and crystallization of Aspergillus flavus urate oxidase
Published in Journal of crystal growth (01-11-2001)“…Interparticle interactions of urate oxidase from Aspergillus flavus have been studied by small-angle X-ray scattering to determine crystallization conditions…”
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Journal Article Conference Proceeding -
3
Massive in Silico Study of Noble Gas Binding to the Structural Proteome
Published in Journal of chemical information and modeling (25-11-2019)“…Noble gases are chemically inert, and it was therefore thought they would have little effect on biology. Paradoxically, it was found that they do exhibit a…”
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4
P-SEA: a new efficient assignment of secondary structure from Cα trace of proteins
Published in Bioinformatics (01-06-1997)“…Motivation: The secondary structure is a key element of architectural organization in proteins. Accurate assignment of the secondary structure elements (SSE)…”
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Recapture of [S]-allantoin, the product of the two-step degradation of uric acid, by urate oxidase
Published in FEBS letters (03-04-2006)“…Urate oxidase from Aspergillus flavus catalyzes the degradation of uric acid to [S]-allantoin through 5-hydroxyisourate as a metastable intermediate. The…”
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6
High-Pressure Macromolecular Crystallography (HPMX): Status and prospects
Published in Biochimica et biophysica acta (01-03-2006)“…Recent technical developments, achievements and prospects of high-pressure (HP) macromolecular crystallography (MX) are reviewed. Technical difficulties…”
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Equilibria between conformational states of the Ras oncogene protein revealed by high-pressure crystallography
Published in Acta crystallographica. Section A, Foundations and advances (23-08-2022)“…Abstract only…”
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Identification of potentially bioactive argon binding sites in protein families
Published in Acta crystallographica. Section A, Foundations and advances (23-08-2022)“…Abstract only…”
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9
Structural Basis for Xenon Inhibition in a Cationic Pentameric Ligand-Gated Ion Channel
Published in PloS one (24-02-2016)“…GLIC receptor is a bacterial pentameric ligand-gated ion channel whose action is inhibited by xenon. Xenon has been used in clinical practice as a potent…”
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10
Novel fluoroalkyl derivatives of selective kappa opioid receptor antagonist JDTic: Design, synthesis, pharmacology and molecular modeling studies
Published in European journal of medicinal chemistry (27-01-2015)“…Novel N- and O-fluoroalkyl derivatives of the highly potent KOR antagonist JDTic were designed and synthesized. Their opioid receptor properties were compared…”
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Beta-breakers: an aperiodic secondary structure
Published in Journal of molecular biology (20-09-1991)“…We have studied the architecture of parallel beta-sheets in proteins and focused on the residues that initiate and terminate the beta-strands. These…”
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12
Structure-Function Perturbation and Dissociation of Tetrameric Urate Oxidase by High Hydrostatic Pressure
Published in Biophysical journal (19-05-2010)“…Structure-function relationships in the tetrameric enzyme urate oxidase were investigated using pressure perturbation. As the active sites are located at the…”
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Protein Crystallography under Xenon and Nitrous Oxide Pressure: Comparison with In Vivo Pharmacology Studies and Implications for the Mechanism of Inhaled Anesthetic Action
Published in Biophysical journal (01-01-2007)“…In contrast with most inhalational anesthetics, the anesthetic gases xenon (Xe) and nitrous oxide (N 2O) act by blocking the N-methyl- d-aspartate (NMDA)…”
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Crystallization and preliminary X-ray diffraction studies of a protective cloned 28 kDa glutathione S-transferase from Schistosoma mansoni
Published in Journal of molecular biology (20-03-1992)“…Crystals of the recombinant 28 kDa glutathione S-transferase from Schistosoma mansoni have been obtained by the hanging-drop method of vapor diffusion from…”
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15
p3 peptide, a truncated form of Aβ devoid of synaptotoxic effect, does not assemble into soluble oligomers
Published in FEBS letters (11-06-2008)“…In previously proposed models of Aβ soluble oligomers, the N-terminal domain Aβ 1–16, which is missing in p3 peptides, protects the hydrophobic core of the…”
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A new tool for the qualitative and quantitative analysis of protein surfaces using B-spline and density of surface neighborhood
Published in Journal of molecular graphics (01-09-1990)“…To improve the qualitative and quantitative analysis of surfaces of protein, two new methods are proposed: one that smoothes the MS surface of Connolly with…”
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Exploring hydrophobic sites in proteins with xenon or krypton
Published in Proteins, structure, function, and bioinformatics (01-01-1998)“…X‐ray diffraction is used to study the binding of xenon and krypton to a variety of crystallised proteins: porcine pancreatic elastase; subtilisin Carlsberg…”
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Salting-In Effects on Urate Oxidase Crystal Design
Published in Crystal growth & design (03-12-2008)“…In this paper, solubility and interactions in solution of the recombinant urate oxidase from Aspergillus flavus, rasburicase, are studied both in the absence…”
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Crystal Structure of the protein drug urate oxidase-inhibitor complex at 2.05 Å resolution
Published in Nature structural biology (01-11-1997)“…The gene coding for urate oxidase, an enzyme that catalyzes the oxidation of uric acid to allantoin, is inactivated in humans. Consequently, urate oxidase is…”
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