Search Results - "Colloby, Sean. J"

Neuropathologically mixed Alzheimer’s and Lewy body disease: burden of pathological protein aggregates differs between clinical phenotypes by Walker, Lauren, McAleese, Kirsty E., Thomas, Alan J., Johnson, Mary, Martin-Ruiz, Carmen, Parker, Craig, Colloby, Sean J., Jellinger, Kurt, Attems, Johannes

“…Multiple different pathological protein aggregates are frequently seen in human postmortem brains and hence mixed pathology is common. Mixed dementia on the…”
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PET imaging of brain amyloid in dementia: a review by Quigley, Harriet, Colloby, Sean J., O'Brien, John T.

“…Objective To review the rapidly expanding literature of amyloid PET imaging with particular attention to Pittsburgh compound‐B (PIB) in Alzheimer's disease…”
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Computational meta-analysis of statistical parametric maps in major depression by Arnone, Danilo, Job, Dominic, Selvaraj, Sudhakar, Abe, Osamu, Amico, Francesco, Cheng, Yuqi, Colloby, Sean J., O'Brien, John T., Frodl, Thomas, Gotlib, Ian H., Ham, Byung-Joo, Kim, M Justin, Koolschijn, P Cédric MP, Périco, Cintia A.-M., Salvadore, Giacomo, Thomas, Alan J., Van Tol, Marie-José, van der Wee, Nic J.A., Veltman, Dick J., Wagner, Gerd, McIntosh, Andrew M.

“…Objective Several neuroimaging meta‐analyses have summarized structural brain changes in major depression using coordinate‐based methods. These methods might…”
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Patterns of cerebellar volume loss in dementia with Lewy bodies and Alzheimer's disease: A VBM-DARTEL study by COLLOBY, Sean J, O'BRIEN, John T, TAYLOR, John-Paul

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Cortical Thickness in Dementia with Lewy Bodies and Alzheimer's Disease: A Comparison of Prodromal and Dementia Stages by Blanc, Frederic, Colloby, Sean J, Philippi, Nathalie, de Pétigny, Xavier, Jung, Barbara, Demuynck, Catherine, Phillipps, Clélie, Anthony, Pierre, Thomas, Alan, Bing, Fabrice, Lamy, Julien, Martin-Hunyadi, Catherine, O'Brien, John T, Cretin, Benjamin, McKeith, Ian, Armspach, Jean-Paul, Taylor, John-Paul

“…To assess and compare cortical thickness (CTh) of patients with prodromal Dementia with Lewy bodies (pro-DLB), prodromal Alzheimer's disease (pro-AD), DLB…”
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Assessment of Regional Gray Matter Loss in Dementia with Lewy Bodies: A Surface-Based MRI Analysis by Watson, Rosie, Ph.D, Colloby, Sean J., Ph.D, Blamire, Andrew M., Ph.D, O’Brien, John T., D.M

“…Objective To compare magnetic resonance imaging (MRI) patterns of cortical thinning in subjects with dementia with Lewy bodies (DLB), Alzheimer's disease (AD),…”
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fMRI resting state networks and their association with cognitive fluctuations in dementia with Lewy bodies by Peraza, Luis R, Kaiser, Marcus, Firbank, Michael, Graziadio, Sara, Bonanni, Laura, Onofrj, Marco, Colloby, Sean J, Blamire, Andrew, O'Brien, John, Taylor, John-Paul

“…Cognitive fluctuations are a core symptom in dementia with Lewy bodies (DLB) and may relate to pathological alterations in distributed brain networks. To test…”
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Consecutive sessions of transcranial direct current stimulation do not remediate visual hallucinations in Lewy body dementia: a randomised controlled trial by Elder, Greg J, Colloby, Sean J, Firbank, Michael J, McKeith, Ian G, Taylor, John-Paul

“…Complex visual hallucinations are common in Lewy body dementia (LBD) and can cause significant patient and caregiver distress. Current treatments are primarily…”
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Relationship Between Cognition, Magnetic Resonance White Matter Hyperintensities, and Cardiovascular Autonomic Changes in Late-Life Depression by Vasudev, Akshya, Ph.D, Saxby, Brian K., Ph.D, O'Brien, John T., F.R.C.Psych., D.M, Colloby, Sean J., Ph.D, Firbank, Michael J., Ph.D, Brooker, Helen, Ph.D, Wesnes, Keith, Ph.D, Thomas, Alan J., Ph.D., M.R.C.Psych

“…Objectives To explore the relationship between specific aspects of cognition, white matter hyperintensities (WMHs), and cardiovascular autonomic parameters in…”
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Cortical thickness and VBM-DARTEL in late-life depression by Colloby, Sean J, Firbank, Michael J, Vasudev, Akshya, Parry, Steve W, Thomas, Alan J, O'Brien, John T

“…Abstract Background Numerous studies have revealed structural brain changes in late life depression, mainly in white matter or whole lobes with few focussing…”
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Relationship of orthostatic blood pressure to white matter hyperintensities and subcortical volumes in late-life depression by Colloby, Sean J., Vasudev, Akshya, O'Brien, John T., Firbank, Michael J., Parry, Steve W., Thomas, Alan J.

“…Structural brain abnormalities are associated with late-life major depression, with numerous studies reporting increased white matter hyperintensities (WMH)…”
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A new visual rating scale for Ioflupane imaging in Lewy body disease by Lloyd, Jim J., Petrides, George, Donaghy, Paul C., Colloby, Sean J., Attems, Johannes, O'Brien, John T., Roberts, Gemma, Thomas, Alan J.

“…Dopaminergic loss on 123I-Ioflupane brain imaging is a recognised biomarker for dementia with Lewy bodies. It is usually assessed using a visual rating scale…”
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Patterns of cerebellar volume loss in dementia with Lewy bodies and Alzheimer׳s disease: A VBM-DARTEL study by Colloby, Sean. J, O׳Brien, John. T, Taylor, John-Paul

“…Abstract Evidence suggests that the cerebellum contributes to cognition as well as motor function. We investigated cerebellar grey matter (GM) and white matter…”
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Parietal white matter lesions in Alzheimer’s disease are associated with cortical neurodegenerative pathology, but not with small vessel disease by McAleese, Kirsty E., Walker, Lauren, Graham, Sophie, Moya, Elisa L. J., Johnson, Mary, Erskine, Daniel, Colloby, Sean J., Dey, Madhurima, Martin-Ruiz, Carmen, Taylor, John-Paul, Thomas, Alan J., McKeith, Ian G., De Carli, Charles, Attems, Johannes

“…Cerebral white matter lesions (WML) encompass axonal loss and demyelination, and the pathogenesis is assumed to be small vessel disease (SVD)-related ischemia…”
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Concomitant neurodegenerative pathologies contribute to the transition from mild cognitive impairment to dementia by McAleese, Kirsty E., Colloby, Sean J., Thomas, Alan J., Al‐Sarraj, Safa, Ansorge, Olaf, Neal, James, Roncaroli, Federico, Love, Seth, Francis, Paul T., Attems, Johannes

“…Introduction The aged brain frequently exhibits multiple pathologies, rather than a single hallmark pathology (pure pathology [PurP]), ranging from…”
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Frontal white matter lesions in Alzheimer’s disease are associated with both small vessel disease and AD-associated cortical pathology by McAleese, Kirsty E., Miah, Mohi, Graham, Sophie, Hadfield, Georgina M., Walker, Lauren, Johnson, Mary, Colloby, Sean J., Thomas, Alan J., DeCarli, Charles, Koss, David, Attems, Johannes

“…Cerebral white matter lesions (WML) encompass axonal loss and demyelination and are assumed to be associated with small vessel disease (SVD)-related ischaemia…”
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Neuropsychiatric symptoms and cognitive profile in mild cognitive impairment with Lewy bodies by Donaghy, Paul C, Taylor, John-Paul, O'Brien, John T, Barnett, Nicola, Olsen, Kirsty, Colloby, Sean J, Lloyd, Jim, Petrides, George, McKeith, Ian G, Thomas, Alan J

“…The accurate clinical characterisation of mild cognitive impairment (MCI) is becoming increasingly important. The aim of this study was to compare the…”
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Neuropathological correlates of dopaminergic imaging in Alzheimer's disease and Lewy body dementias by COLLOBY, Sean J, MCPARLAND, Shane, O'BRIEN, John T, ATTEMS, Johannes

“…Investigation of dopaminergic transporter loss in vivo using (123)I-N-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl) nortropane single photon emission computed…”
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Diagnostic accuracy of dopaminergic imaging in prodromal dementia with Lewy bodies by Thomas, Alan J, Donaghy, Paul, Roberts, Gemma, Colloby, Sean J, Barnett, Nicky A, Petrides, George, Lloyd, Jim, Olsen, Kirsty, Taylor, John-Paul, McKeith, Ian, O'Brien, John T

“…Dopaminergic imaging has high diagnostic accuracy for dementia with Lewy bodies (DLB) at the dementia stage. We report the first investigation of dopaminergic…”
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Accuracy of Cardiac Innervation Scintigraphy for Mild Cognitive Impairment With Lewy Bodies by Roberts, Gemma, Durcan, Rory, Donaghy, Paul C., Lawley, Sarah, Ciafone, Joanna, Hamilton, Calum A., Colloby, Sean J., Firbank, Michael J., Allan, Louise, Barnett, Nicola, Barker, Sally, Howe, Kim, Ali, Tamir, Petrides, George S., Lloyd, Jim, Taylor, John-Paul, O'Brien, John, Thomas, Alan J.

“…To provide evidence that cardiac I-123-metaiodobenzylguanidine sympathetic innervation imaging (MIBG) scintigraphy differentiates probable mild cognitive…”
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