Search Results - "Collins, VP"

Tandem duplication producing a novel oncogenic BRAF fusion gene defines the majority of pilocytic astrocytomas by Jones, David T W, Kocialkowski, Sylvia, Liu, Lu, Pearson, Danita M, Bäcklund, L Magnus, Ichimura, Koichi, Collins, V Peter

“…Brain tumors are the most common solid tumors of childhood, and pilocytic astrocytomas (PA) are the most common central nervous system tumor in 5 to 19 year…”
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Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas by Kool, Marcel, Korshunov, Andrey, Remke, Marc, Jones, David T. W., Schlanstein, Maria, Northcott, Paul A., Cho, Yoon-Jae, Koster, Jan, Schouten-van Meeteren, Antoinette, van Vuurden, Dannis, Clifford, Steven C., Pietsch, Torsten, von Bueren, Andre O., Rutkowski, Stefan, McCabe, Martin, Collins, V. Peter, Bäcklund, Magnus L., Haberler, Christine, Bourdeaut, Franck, Delattre, Olivier, Doz, Francois, Ellison, David W., Gilbertson, Richard J., Pomeroy, Scott L., Taylor, Michael D., Lichter, Peter, Pfister, Stefan M.

“…Medulloblastoma is the most common malignant brain tumor in childhood. Molecular studies from several groups around the world demonstrated that medulloblastoma…”
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IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas by Ichimura, Koichi, Pearson, Danita M, Kocialkowski, Sylvia, Bäcklund, L Magnus, Chan, Raymond, Jones, David T W, Collins, V Peter

“…We screened exon 4 of the gene isocitrate dehydrogenase 1 (NADP+), soluble (IDH1) for mutations in 596 primary intracranial tumors of all major types. Codon…”
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Deletion Mapping of a Locus on Human Chromosome 22 Involved in the Oncogenesis of Meningioma by Dumanski, Jan P., Carlbom, Elisabeth, Collins, V. Peter, Nordenskjöld, Magnus

“…The genotypes were analyzed at 11 polymorphic DNA loci (restriction fragment length alleles) on chromosome 22 in tumor and normal tissue from 35 unrelated…”
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Brain tumours: classification and genes by Collins, V P

“…A patient's diagnosis is based on the most malignant part of the tumour. [...]it is of the utmost importance to sample the tumour adequately in order to…”
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Pathology and molecular genetics of astrocytic gliomas by REIFENBERGER, Guido, COLLINS, Vincent Peter

“…Astrocytic gliomas are the most common primary brain tumours. Here we summarize the characteristic neuropathological features of the different types of…”
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Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain by Geisenberger, Christoph, Mock, Andreas, Warta, Rolf, Rapp, Carmen, Schwager, Christian, Korshunov, Andrey, Nied, Ann-Katrin, Capper, David, Brors, Benedikt, Jungk, Christine, Jones, David, Collins, V. Peter, Ichimura, Koichi, Bäcklund, L. Magnus, Schnabel, Elena, Mittelbron, Michel, Lahrmann, Bernd, Zheng, Siyuan, Verhaak, Roel G. W., Grabe, Niels, Pfister, Stefan M., Hartmann, Christian, von Deimling, Andreas, Debus, Jürgen, Unterberg, Andreas, Abdollahi, Amir, Herold-Mende, Christel

“…Glioblastoma (GBM) is a devastating tumor and few patients survive beyond 3 years. Defining the molecular determinants underlying long-term survival is…”
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Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors by Möllemann, Maria, Wolter, Marietta, Felsberg, Jörg, Collins, V. Peter, Reifenberger, Guido

“…Allelic losses on the chromosome arms 1p and 19q have been associated with favorable response to chemotherapy and good prognosis in anaplastic…”
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PO395 YEAR SURVIVAL WITH GLIOBLASTOMA: A NATIONAL PERSPECTIVE by Brodbelt, A., Greenberg, D., Williams, M., Karabatsou, T., Miller, S., Collins, VP

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MGMT CpG island is invariably methylated in adult astrocytic and oligodendroglial tumors with IDH1 or IDH2 mutations by Mulholland, Shani, Pearson, Danita M., Hamoudi, Rifat A., Malley, Deborah S., Smith, Caroline M., Weaver, Jamie M.J., Jones, David T.W., Kocialkowski, Sylvia, Bäcklund, L. Magnus, Collins, V. Peter, Ichimura, Koichi

“…We have previously identified a region containing 16 CpGs within the MGMT CpG islands which is critical for the transcriptional control of MGMT (Malley, Acta…”
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Amplification of 2p as a genomic marker for transformation in lymphoma by Kwiecinska, Anna, Ichimura, Koichi, Berglund, Mattias, Dinets, Andrii, Sulaiman, Luqman, Collins, V. Peter, Larsson, Catharina, Porwit, Anna, Lagercrantz, Svetlana Bajalica

“…To outline further genetic mechanisms of transformation from follicular lymphoma (FL) to diffuse large B‐cell lymphoma (DLBCL), we have performed whole genome…”
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A20 deletion is associated with copy number gain at the TNFA/B/C locus and occurs preferentially in translocation-negative MALT lymphoma of the ocular adnexa and salivary glands by Chanudet, E, Ye, H, Ferry, J, Bacon, CM, Adam, P, Müller-Hermelink, HK, Radford, J, Pileri, SA, Ichimura, K, Collins, VP, Hamoudi, RA, Nicholson, AG, Wotherspoon, AC, Isaacson, PG, Du, MQ

“…The genetic basis of MALT lymphoma is largely unknown. Characteristic chromosomal translocations are frequently associated with gastric and pulmonary cases,…”
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Distinct patterns of 1p and 19q alterations identify subtypes of human gliomas that have different prognoses by Vogazianou, Artemis P., Chan, Raymond, Bäcklund, L. Magnus, Pearson, Danita M., Liu, Lu, Langford, Cordelia F., Gregory, Simon G., Collins, V. Peter, Ichimura, Koichi

“…We studied the status of chromosomes 1 and 19 in 363 astrocytic and oligodendroglial tumors. Whereas the predominant pattern of copy number abnormality was a…”
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Molecular pathogenesis of astrocytic tumours by Ichimura, Koichi, Ohgaki, Hiroko, Kleihues, Paul, Collins, V Peter

“…Our current knowledge of the molecular pathogenesis of the diffuse adult astrocytic tumours is vast if compared to 20 years ago, yet we are far from…”
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Optimizing sharing of hospital biobank samples by Riegman, Peter H J, de Jong, Bas, Daidone, Maria Grazia, Söderström, Tommy, Thompson, James, Hall, Jacqueline A, Mendy, Maimuna, Ten Hoeve, Jelle, Broeks, Annegien, Reed, Wenche, Morente, Manuel M, López-Guerrero, José Antonio, Collins, V Peter, Rogan, Jane, Ringborg, Ulrik

“…Implementing technical guidelines and standards as well as ways to boost cooperation should facilitate sharing of hospital biobank samples…”
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Alterations of the tumor suppressor genes CDKN2A (p16(INK4a)), p14(ARF), CDKN2B (p15(INK4b)), and CDKN2C (p18(INK4c)) in atypical and anaplastic meningiomas by Boström, J, Meyer-Puttlitz, B, Wolter, M, Blaschke, B, Weber, R G, Lichter, P, Ichimura, K, Collins, V P, Reifenberger, G

“…We investigated 67 meningothelial tumors (20 benign meningiomas, 34 atypical meningiomas, and 13 anaplastic meningiomas) for losses of genetic information from…”
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1p36 is a preferential target of chromosome 1 deletions in astrocytic tumours and homozygously deleted in a subset of glioblastomas by Ichimura, K, Vogazianou, A P, Liu, L, Pearson, D M, Bäcklund, L M, Plant, K, Baird, K, Langford, C F, Gregory, S G, Collins, V P

“…Astrocytic, oligodendroglial and mixed gliomas are the commonest gliomas in adults. They have distinct phenotypes and clinical courses, but as they exist as a…”
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Adult grade II diffuse astrocytomas are genetically distinct from and more aggressive than their paediatric counterparts by Jones, David T. W., Mulholland, Shani A., Pearson, Danita M., Malley, Deborah S., Openshaw, Samuel W. S., Lambert, Sally R., Liu, Lu, Bäcklund, L. Magnus, Ichimura, Koichi, Collins, V. Peter

“…Diffuse astrocytomas (WHO grade II) typically present as slow-growing tumours showing significant cellular differentiation, but possessing a tendency towards…”
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Global amplification of mRNA by template‐switching PCR: linearity and application to microarray analysis by Petalidis, L., Bhattacharyya, S., Morris, G. A., Collins, V. P., Freeman, T. C., Lyons, P. A.

“…Conventional approaches to target labelling for expression microarray analysis typically require relatively large amounts of total RNA, a serious limitation…”
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Improved grading and survival prediction of human astrocytic brain tumors by artificial neural network analysis of gene expression microarray data by Petalidis, Lawrence P, Oulas, Anastasis, Backlund, Magnus, Wayland, Matthew T, Liu, Lu, Plant, Karen, Happerfield, Lisa, Freeman, Tom C, Poirazi, Panayiota, Collins, V Peter

“…Histopathologic grading of astrocytic tumors based on current WHO criteria offers a valuable but simplified representation of oncologic reality and is often…”
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