Search Results - "Collins, Hannah Y."
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Spatiotemporal Control of CNS Myelination by Oligodendrocyte Programmed Cell Death through the TFEB-PUMA Axis
Published in Cell (13-12-2018)“…Nervous system function depends on proper myelination for insulation and critical trophic support for axons. Myelination is tightly regulated spatially and…”
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Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia
Published in Cell reports (Cambridge) (04-06-2019)“…Microglia, the brain's immune cells, maintain homeostasis and sense pathological changes by continuously surveying the parenchyma with highly motile large…”
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Isolation and Culture of Rodent Microglia to Promote a Dynamic Ramified Morphology in Serum-free Medium
Published in Journal of visualized experiments (09-03-2018)“…Microglia represent 5 - 10% of all central nervous system (CNS) cells and are increasingly drawing attention due to their contributions during development,…”
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Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis
Published in Nature communications (21-08-2018)“…Oligodendrocyte progenitor cells (OPC) undergo asymmetric cell division (ACD) to generate one OPC and one differentiating oligodendrocyte (OL) progeny. Loss of…”
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Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures
Published in Neuron (Cambridge, Mass.) (17-05-2017)“…Microglia, the resident macrophages of the CNS, engage in various CNS-specific functions that are critical for development and health. To better study…”
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Fishing for a balance: Toward promyelinating drug discovery
Published in Cell chemical biology (20-10-2022)“…In this issue, Häberlein et al. demonstrate a role for GPR17 in regulating zebrafish oligodendrocyte differentiation. Zebrafish expressing a humanized GPR17…”
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Diversity of microglial transcriptional responses during opioid exposure and neuropathic pain
Published in Pain (Amsterdam) (01-11-2024)“…Microglia take on an altered morphology during chronic opioid treatment. This morphological change is broadly used to identify the activated microglial state…”
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Isolation and Culture of Rodent Microglia to Promote a Dynamic Ramified Morphology in Serum-free Medium
Published in Journal of visualized experiments (09-03-2018)Get full text
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