Search Results - "Collins, Deborah J"

Efficacy of CMX001 against Herpes Simplex Virus Infections in Mice and Correlations with Drug Distribution Studies by Quenelle, Debra C., Lampert, Bernhardt, Collins, Deborah J., Rice, Terri L., Painter, George R., Kern, Earl R.

“…CMX001, an orally active lipid conjugate of cidofovir, is 50 times more active in vitro against herpes simplex virus (HSV) replication than acyclovir or…”
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Oral Treatment of Cowpox and Vaccinia Virus Infections in Mice with Ether Lipid Esters of Cidofovir by Quenelle, Debra C, Collins, Deborah J, Wan, W Brad, Beadle, James R, Hostetler, Karl Y, Kern, Earl R

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Effect of Oral Treatment with Hexadecyloxypropyl-[(S)-9-(3-Hydroxy-2- Phosphonylmethoxypropyl)Adenine] [(S)-HPMPA] or Octadecyloxyethyl-(S)-HPMPA on Cowpox or Vaccinia Virus Infections in Mice by QUENELLE, Debra C, COLLINS, Deborah J, HERROD, Bridgett P, KEITH, Kathy A, TRAHAN, Julissa, BEADLE, James R, HOSTETLER, Karl Y, KERN, Earl R

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Oral Treatment of Murine Cytomegalovirus Infections with Ether Lipid Esters of Cidofovir by KERN, Earl R, COLLINS, Deborah J, WAN, W. Brad, BEADLE, James R, HOSTETLER, Karl Y, QUENELLE, Debra C

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Efficacy of Multiple- or Single-Dose Cidofovir against Vaccinia and Cowpox Virus Infections in Mice by QUENELLE, Debra C, COLLINS, Deborah J, KERN, Earl R

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Efficacy of pritelivir and acyclovir in the treatment of herpes simplex virus infections in a mouse model of herpes simplex encephalitis by Quenelle, Debra C., Birkmann, Alexander, Goldner, Thomas, Pfaff, Tamara, Zimmermann, Holger, Bonsmann, Susanne, Collins, Deborah J., Rice, Terri L., Prichard, Mark N.

“…Pritelivir, a helicase-primase inhibitor, has excellent in vitro and in vivo activity against human herpes simplex virus (HSV). Mice lethally infected with HSV…”
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Evaluation of AD472, a live attenuated recombinant herpes simplex virus type 2 vaccine in guinea pigs by Prichard, Mark N., Kaiwar, Ravi, Jackman, Winthrop T., Quenelle, Debra C., Collins, Deborah J., Kern, Earl R., Kemble, George M., Spaete, Richard R.

“…An attenuated recombinant herpes simplex virus type 2 (HSV-2), designated as AD472, was constructed by deleting both copies of the γ 134.5 gene, UL55-56,…”
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Efficacy of Orally Administered Low Dose N-methanocarbathymidine against Lethal Herpes Simplex Virus Type-2 Infections of Mice by Quenelle, Debra C, Collins, Deborah J, Rice, Terri L, Rahman, Aquilur, Glazer, Robert

“…Background: N-methanocarbathymidine (N-MCT) has previously been shown to be effective against lethal orthopoxvirus and herpes simplex virus type-1 infections…”
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Effect of immunization with herpes simplex virus type-1 (HSV-1) glycoprotein D (gD) plus the immune enhancer GPI-0100 on infection with HSV-1 or HSV-2 by Quenelle, Debra C., Collins, Deborah J., Marciani, Dante J., Kern, Earl R.

“…These studies were performed to determine the effects of GPI-0100, a semi synthetic Quillaja Saponin analog, formulated with herpes simplex virus type-1…”
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Effect of oral treatment with ( S)-HPMPA, HDP-( S)-HPMPA or ODE-( S)-HPMPA on replication of murine cytomegalovirus (MCMV) or human cytomegalovirus (HCMV) in animal models by Quenelle, Debra C., Collins, Deborah J., Pettway, Latisha R., Hartline, Caroll B., Beadle, James R., Wan, W. Brad, Hostetler, Karl Y., Kern, Earl R.

“…We utilized BALB/c mice infected with murine CMV (MCMV) or severe combined immunodeficient (SCID) mice implanted with human fetal tissue and infected with HCMV…”
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Effect of an immune enhancer, GPI-0100, on vaccination with live attenuated herpes simplex virus (HSV) type 2 or glycoprotein D on genital HSV-2 infections of guinea pigs by Quenelle, Debra C., Collins, Deborah J., Rice, Terri L., Prichard, Mark N., Marciani, Dante J., Kern, Earl R.

“…These studies were performed to determine the effect of AD-472, an attenuated human herpes simplex virus (HSV) type 2 or HSV-2 glycoprotein D (gD) when…”
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Cutaneous infections of mice with vaccinia or cowpox viruses and efficacy of cidofovir by Quenelle, Debra C, Collins, Deborah J, Kern, Earl R

“…Orthopoxviruses, including smallpox, monkeypox and molluscipox, pose risks to human health through bioterrorist acts or natural transmission. There is no…”
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Oral Treatment of Cowpox and Vaccinia Virus Infections in Mice with Ether Lipid Esters of Cidofovir by Quenelle, Debra C, Collins, Deborah J, Wan, W. Brad, Beadle, James R, Hostetler, Karl Y, Kern, Earl R

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Oral treatment of cowpox and vaccinia virus infections in mice with ether lipid esters of cidofovir by QUENELLE, Debra C, COLLINS, Deborah J, WAN, W. Brad, BEADLE, James R, HOSTETLER, Karl Y, KERN, Earl R

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