Search Results - "Collin‐Osdoby, Patricia"

CCR1 Chemokines Promote the Chemotactic Recruitment, RANKL Development, and Motility of Osteoclasts and Are Induced by Inflammatory Cytokines in Osteoblasts by Yu, Xuefeng, Huang, Yuefang, Collin‐Osdoby, Patricia, Osdoby, Philip

“…Chemoattractants that recruit OC precursors to locally inflamed sites of resorption are not well known. A chemokine receptor, CCR1, was expressed in OC…”
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Stromal Cell‐Derived Factor‐1 (SDF‐1) Recruits Osteoclast Precursors by Inducing Chemotaxis, Matrix Metalloproteinase‐9 (MMP‐9) Activity, and Collagen Transmigration by Yu, Xuefeng, Huang, Yuefang, Collin‐Osdoby, Patricia, Osdoby, Philip

“…Signals targeting OCs to bone and resorption sites are not well characterized. A chemoattractant receptor (CXCR4), highly expressed in murine OC precursors,…”
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RANKL-mediated osteoclast formation from murine RAW 264.7 cells by Collin-Osdoby, Patricia, Osdoby, Philip

“…Extensive research efforts over the years have provided us with great insights into how bone-resorbing osteoclasts (OCs) develop and function and, based on…”
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Regulation of Vascular Calcification by Osteoclast Regulatory Factors RANKL and Osteoprotegerin by Collin-Osdoby, Patricia

“…Vascular calcification often occurs with advancing age, atherosclerosis, various metabolic disorders such as diabetes mellitus and end-stage renal disease, or…”
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Vascular Biology and the Skeleton by Brandi, Maria Luisa, Collin‐Osdoby, Patricia

“…This overview is intended to highlight the potential roles of various paracrine interactions between bone endothelium and differentiated bone cells during…”
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Role of vascular endothelial cells in bone biology by Collin-Osdoby, P

“…Bone development and remodeling depend on complex interactions between bone-forming osteoblasts, bone-degrading osteoclasts, and other cells present within the…”
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Bone cell function, regulation, and communication: a role for nitric oxide by Collin-Osdoby, P, Nickols, G A, Osdoby, P

“…A large array of factors serve as vital communication links between cells and the characterization, regulation, and mechanisms of action of such factors are…”
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Human Microvascular Endothelial Cell Activation by IL‐1 and TNF‐α Stimulates the Adhesion and Transendothelial Migration of Circulating Human CD14+ Monocytes That Develop With RANKL Into Functional Osteoclasts by Kindle, Libby, Rothe, Linda, Kriss, Michael, Osdoby, Philip, Collin‐Osdoby, Patricia

“…Circulating pre‐OCs may be recruited to locally inflamed sites through specific interactions with activated microvasculature. We found that HMVECs stimulated…”
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Cellular Mechanism of Decreased Bone in Brtl Mouse Model of OI: Imbalance of Decreased Osteoblast Function and Increased Osteoclasts and Their Precursors by Uveges, Thomas E, Collin‐Osdoby, Patricia, Cabral, Wayne A, Ledgard, Felicia, Goldberg, Leah, Bergwitz, Clemens, Forlino, Antonella, Osdoby, Philip, Gronowicz, Gloria A, Marini, Joan C

“…The Brtl mouse, a knock‐in model for moderately severe osteogenesis imperfecta (OI), has a G349C substitution in half of type I collagen α1(I) chains. We…”
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Proinflammatory agents, IL-8 and IL-10, upregulate inducible nitric oxide synthase expression and nitric oxide production in avian osteoclast-like cells by Sunyer, Teresa, Rothe, Linda, Jiang, Xinsheng, Osdoby, Philip, Collin-Osdoby, Patricia

“…Nitric oxide synthase (NOS) isoenzymes generate nitric oxide (NO), a sensitive multifunctional intercellular signal molecule. High NO levels are produced by an…”
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Basic Fibroblast Growth Factor Stimulates Osteoclast Recruitment, Development, and Bone Pit Resorption in Association With Angiogenesis In Vivo on the Chick Chorioallantoic Membrane and Activates Isolated Avian Osteoclast Resorption In Vitro by Collin‐Osdoby, Patricia, Rothe, Linda, Bekker, Simon, Anderson, Fred, Huang, Yuefang, Osdoby, Philip

“…Increased local osteoclast (OC)‐mediated bone resorption coincides with angiogenesis in normal bone development and fracture repair, as well as in pathological…”
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Estrogen's bone-protective effects may involve differential IL-1 receptor regulation in human osteoclast-like cells by Sunyer, T, Lewis, J, Collin-Osdoby, P, Osdoby, P

“…Declining estrogen levels during the first postmenopausal decade lead to rapid bone loss and increased fracture risk that can be reversed by estrogen…”
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Decreased Nitric Oxide Levels Stimulate Osteoclastogenesis and Bone Resorption Both in Vitro and in Vivo on the Chick Chorioallantoic Membrane in Association with Neoangiogenesis by Collin‐Osdoby, Patricia, Rothe, Linda, Bekker, Simon, Anderson, Fred, Osdoby, Philip

“…High nitric oxide (NO) levels inhibit osteoclast (OC)‐mediated bone resorption in vivo and in vitro, and nitrate donors protect against estrogen‐deficient bone…”
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RANKL Stimulates Inducible Nitric-oxide Synthase Expression and Nitric Oxide Production in Developing Osteoclasts by Zheng, Hong, Yu, Xuefeng, Collin-Osdoby, Patricia, Osdoby, Philip

“…Nitric oxide (NO) is a multifunctional signaling molecule and a key vasculoprotective and potential osteoprotective factor. NO regulates normal bone remodeling…”
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Osteoclast‐specific monoclonal antibodies coupled to magnetic beads provide a rapid and efficient method of purifying avian osteoclasts by Collin‐Osdoby, Patricia, Oursler, Merry Jo, Webber, David, Osdoby, Philip

“…Osteoclasts are the major cell type responsible for normal and pathologic bone resorption. Obtaining highly purified populations of these multinucleated cells…”
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Receptor Activator of NF-κB and Osteoprotegerin Expression by Human Microvascular Endothelial Cells, Regulation by Inflammatory Cytokines, and Role in Human Osteoclastogenesis by Collin-Osdoby, Patricia, Rothe, Linda, Anderson, Fred, Nelson, Maureen, Maloney, William, Osdoby, Philip

“…The receptor activator of NF-κB (RANKL) is the essential signal required for full osteoclast (OC) development, activation, and survival. RANKL is highly…”
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Inhibition of Avian Osteoclast Bone Resorption by Monoclonal Antibody 121F: A Mechanism Involving the Osteoclast Free Radical System by Collin‐Osdoby, Patricia, Li, Li, Rothe, Linda, Anderson, Fred, Kirsch, David, Oursler, Merry Jo, Osdoby, Philip

“…Osteoclasts generate high levels of superoxide anions during bone resorption that contribute to the degradative process, although excessive levels of this free…”
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Stromal cell-derived factor-1 binding to its chemokine receptor CXCR4 on precursor cells promotes the chemotactic recruitment, development and survival of human osteoclasts by Wright, Lorinda M., Maloney, William, Yu, Xuefeng, Kindle, Libby, Collin-Osdoby, Patricia, Osdoby, Philip

“…Osteoclasts (Oc) derive from hematopoietic precursors present in the circulation and bone marrow, and they differentiate into multinucleated bone-resorbing…”
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In vitro structural and functional relationships between preosteoclastic and bone endothelial cells: a juxtacrine model for migration and adhesion of osteoclast precursors by Formigli, L, Orlandini, S Z, Benvenuti, S, Masi, L, Pinto, A, Gattei, V, Bernabei, P A, Robey, P G, Collin-Osdoby, P, Brandi, M L

“…The role of vascularization in the process of bone resorption has not been clarified. The interactions between vascular endothelium and osteoclast progenitors…”
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Osteoclast 121F antigen expression during osteoblast conditioned medium induction of osteoclast‐like cells in vitro: Relationship to calcitonin responsiveness, tartrate resistant acid phosphatase levels, and bone resorptive activity by Collin‐Osdoby, Patricia, Oursler, Merry Jo, Rothe, Linda, Webber, David, Anderson, Fred, Osdoby, Philip

“…Osteoclast differentiation from hematopoietic precursors into multinucleated cells uniquely capable of removing the organic and inorganic components of bone…”
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