Search Results - "Collier, Paul"
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Single-cell isoform RNA sequencing characterizes isoforms in thousands of cerebellar cells
Published in Nature biotechnology (01-12-2018)“…Full-length spliced RNA isoforms are identified in thousands of single cerebellar cells. Full-length RNA sequencing (RNA-Seq) has been applied to bulk tissue,…”
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2
Achieving Socio-Economic Convergence in Europe
Published in Inter economics (2020)“…The origins of European populism are two socio-economic divergences that began around 1980 and have been at their most extreme in Britain. One is spatial, the…”
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Poverty Reduction in Africa
Published in Proceedings of the National Academy of Sciences - PNAS (23-10-2007)“…Poverty in Africa has been rising for the last quarter-century, while it has been falling in the rest of the developing world. Africa's distinctive problem is…”
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4
Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy
Published in Cell (18-05-2017)“…Dormant hematopoietic stem cells (dHSCs) are atop the hematopoietic hierarchy. The molecular identity of dHSCs and the mechanisms regulating their maintenance…”
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Microfluidic isoform sequencing shows widespread splicing coordination in the human transcriptome
Published in Genome research (01-02-2018)“…Understanding transcriptome complexity is crucial for understanding human biology and disease. Technologies such as Synthetic long-read RNA sequencing…”
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Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids
Published in Molecular psychiatry (01-03-2022)“…Due to an inability to ethically access developing human brain tissue as well as identify prospective cases, early-arising neurodevelopmental and cell-specific…”
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A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
Published in Nature communications (19-01-2021)“…Splicing varies across brain regions, but the single-cell resolution of regional variation is unclear. We present a single-cell investigation of differential…”
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INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models
Published in PloS one (21-04-2020)“…Alterations in fibroblast growth factor receptor (FGFR) genes have been identified as potential driver oncogenes. Pharmacological targeting of FGFRs may…”
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mRNA 3′ uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome
Published in Nature (London) (17-08-2017)“…TUT4 and TUT7 mediate 3′ uridylation of mRNA transcripts, preferentially those with short poly(A) tails; in the absence of TUT4 and TUT7, oocytes cannot mature…”
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10
Resource Rents, Governance, and Conflict
Published in The Journal of conflict resolution (01-08-2005)“…Case studies as well as cross-country studies suggest that countries with an abundance of natural resources are more prone to violent conflict. This collection…”
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Post-Conflict Risks
Published in Journal of peace research (01-07-2008)“…Post-conflict societies face two distinctive challenges: economic recovery and reduction of the risk of a recurring conflict. Aid and policy reforms have been…”
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Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue
Published in Nature biotechnology (01-07-2022)“…Single-nuclei RNA sequencing characterizes cell types at the gene level. However, compared to single-cell approaches, many single-nuclei cDNAs are purely…”
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13
Balancing creativity and organisational performance in an advertising agency network: A case study
Published in Journal of marketing communications (17-11-2021)“…While interest in international advertising campaigns continues to attract considerable research interest, the management of advertising agencies…”
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14
Migration, Diasporas and Culture: An Empirical Investigation
Published in Kyklos (Basel) (01-02-2018)“…Summary Using a gravity model, we examine the dynamics of migration from developing to OECD countries. Origin and destination countries are characterized by…”
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15
Prevention and treatment of dilator injuries during central venous catheter placement
Published in Journal of vascular surgery. Venous and lymphatic disorders (New York, NY) (01-11-2019)“…AbstractBackroundMisuse of vascular dilators during the placement of central venous catheters has been infrequently reported and can lead to devastating…”
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Probing the Role of a Non‐Thermal Plasma (NTP) in the Hybrid NTP Catalytic Oxidation of Methane
Published in Angewandte Chemie International Edition (01-08-2017)“…Three recurring hypotheses are often used to explain the effect of non‐thermal plasmas (NTPs) on NTP catalytic hybrid reactions; namely, modification or…”
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Rebellion as a Quasi-Criminal Activity
Published in The Journal of conflict resolution (01-12-2000)“…Economic models of rebellion usually treat it as a form of crime or banditry. However, the analogy is not developed. This article treats rebellion as a…”
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Unbiased classification of mosquito blood cells by single-cell genomics and high-content imaging
Published in Proceedings of the National Academy of Sciences - PNAS (07-08-2018)“…Mosquito blood cells are immune cells that help control infection by vector-borne pathogens. Despite their importance, little is known about mosquito blood…”
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The Janus kinase 2 inhibitor fedratinib inhibits thiamine uptake: a putative mechanism for the onset of Wernicke's encephalopathy
Published in Drug metabolism and disposition (01-10-2014)“…The clinical development of fedratinib, a Janus kinase (JAK2) inhibitor, was terminated after reports of Wernicke's encephalopathy in myelofibrosis patients…”
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Selective inhibition of JAK1 and JAK2 is efficacious in rodent models of arthritis: preclinical characterization of INCB028050
Published in The Journal of immunology (1950) (01-05-2010)“…Inhibiting signal transduction induced by inflammatory cytokines offers a new approach for the treatment of autoimmune diseases such as rheumatoid arthritis…”
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