Search Results - "Collier, Gracen E"
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An in-depth examination of Per- and Polyfluoroalkyl (PFAS) effects on transporters, with emphasis on the ABC superfamily: A critical review
Published in Toxicology (Amsterdam) (01-11-2024)“…Per- and polyfluoroalkyl (PFAS) substances are a type of chemical compound unique for their multiple carbon-fluorine bonds, imbuing them with strength and…”
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A loss‐of‐function cysteine mutant in fibulin‐3 (EFEMP1) forms aberrant extracellular disulfide‐linked homodimers and alters extracellular matrix composition
Published in Human mutation (01-12-2022)“…Fibulin‐3 (F3 or EFEMP1) is a disulfide‐rich, secreted glycoprotein necessary for maintaining extracellular matrix (ECM) and connective tissue integrity. Three…”
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Development of a New DHFR-Based Destabilizing Domain with Enhanced Basal Turnover and Applicability in Mammalian Systems
Published in ACS chemical biology (21-10-2022)“…Destabilizing domains (DDs) are an attractive strategy allowing for positive post-transcriptional small molecule-regulatable control of a fusion protein’s…”
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GSK3 inhibition reduces ECM production and prevents age-related macular degeneration-like pathology
Published in JCI insight (08-08-2024)“…Malattia Leventinese/Doyne honeycomb retinal dystrophy (ML/DHRD) is an age-related macular degeneration-like (AMD-like) retinal dystrophy caused by an…”
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