Search Results - "Colli, L."

Asian water buffalo: domestication, history and genetics by Zhang, Y., Colli, L., Barker, J. S. F.

“…Summary The domestic Asian water buffalo (Bubalus bubalis) is found on all five continents, with a global population of some 202 million. The livelihoods of…”
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The human pancreatic islet transcriptome: expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines by Eizirik, Décio L, Sammeth, Michael, Bouckenooghe, Thomas, Bottu, Guy, Sisino, Giorgia, Igoillo-Esteve, Mariana, Ortis, Fernanda, Santin, Izortze, Colli, Maikel L, Barthson, Jenny, Bouwens, Luc, Hughes, Linda, Gregory, Lorna, Lunter, Gerton, Marselli, Lorella, Marchetti, Piero, McCarthy, Mark I, Cnop, Miriam

“…Type 1 diabetes (T1D) is an autoimmune disease in which pancreatic beta cells are killed by infiltrating immune cells and by cytokines released by these cells…”
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SARS-CoV-2 Receptor Angiotensin I-Converting Enzyme Type 2 (ACE2) Is Expressed in Human Pancreatic β -Cells and in the Human Pancreas Microvasculature by Fignani, Daniela, Licata, Giada, Brusco, Noemi, Nigi, Laura, Grieco, Giuseppina E, Marselli, Lorella, Overbergh, Lut, Gysemans, Conny, Colli, Maikel L, Marchetti, Piero, Mathieu, Chantal, Eizirik, Decio L, Sebastiani, Guido, Dotta, Francesco

“…Increasing evidence demonstrated that the expression of Angiotensin I-Converting Enzyme type 2 (ACE2) is a necessary step for SARS-CoV-2 infection…”
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High performance computation of landscape genomic models including local indicators of spatial association by Stucki, S., Orozco‐terWengel, P., Forester, B. R., Duruz, S., Colli, L., Masembe, C., Negrini, R., Landguth, E., Jones, M. R., Bruford, M. W., Taberlet, P., Joost, S.

“…With the increasing availability of both molecular and topo‐climatic data, the main challenges facing landscape genomics – that is the combination of landscape…”
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On the ratio of dynamic topography and gravity anomalies in a dynamic Earth by Colli, L., Ghelichkhan, S., Bunge, H.‐P.

“…Growing evidence from a variety of geologic indicators points to significant topography maintained convectively by viscous stresses in the mantle. However,…”
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Impact of model inconsistencies on reconstructions of past mantle flow obtained using the adjoint method by Colli, L, Bunge, H-P, Oeser, J

“…SUMMARY The adjoint method is a powerful technique to compute sensitivities (Fréchet derivatives) with respect to model parameters, allowing one to solve…”
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Identification of genomic regions associated with total and progressive sperm motility in Italian Holstein bulls by Ramirez-Diaz, J., Cenadelli, S., Bornaghi, V., Bongioni, G., Montedoro, S.M., Achilli, A., Capelli, C., Rincon, J.C., Milanesi, M., Passamonti, M.M., Colli, L., Barbato, M., Williams, J.L., Marsan, P. Ajmone

“…Sperm motility is directly related to the ability of sperm to move through the female reproductive tract to reach the ovum. Sperm motility is a complex trait…”
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Rapid South Atlantic spreading changes and coeval vertical motion in surrounding continents: Evidence for temporal changes of pressure-driven upper mantle flow by Colli, L., Stotz, I., Bunge, H.-P., Smethurst, M., Clark, S., Iaffaldano, G., Tassara, A., Guillocheau, F., Bianchi, M. C.

“…The South Atlantic region displays (1) a topographic gradient across the basin, with Africa elevated relative to South America, (2) a bimodal spreading history…”
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Robust global mantle flow trajectories and their validation via dynamic topography histories by Taiwo, A, Bunge, H-P, Schuberth, B S A, Colli, L, Vilacis, B

“…SUMMARY The ability to construct time-trajectories of mantle flow is crucial to move from studies of instantaneous to time-dependent earth models and to…”
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Molecular Footprints of the Immune Assault on Pancreatic Beta Cells in Type 1 Diabetes by Colli, Maikel L, Szymczak, Florian, Eizirik, Decio L

“…Type 1 diabetes (T1D) is a chronic disease caused by the selective destruction of the insulin-producing pancreatic beta cells by infiltrating immune cells. We…”
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GRACE gravity data help constraining seismic models of the 2004 Sumatran earthquake by Cambiotti, G., Bordoni, A., Sabadini, R., Colli, L.

“…The analysis of Gravity Recovery and Climate Experiment (GRACE) Level 2 data time series from the Center for Space Research (CSR) and GeoForschungsZentrum…”
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Post-subduction tectonics induced by extension from a lithospheric drip by Pilia, S., Davies, D. R., Hall, R., Bacon, C. A., Gilligan, A., Greenfield, T., Tongkul, F., Kramer, S. C., Wilson, C. R., Ghelichkhan, S., Cornwell, D. G., Colli, L., Rawlinson, N.

“…Subduction termination leads to complex tectonic and geological activity, with the observational record often including clear evidence for exhumation,…”
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PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon-γ–Induced Pancreatic β-Cell Apoptosis by MOORE, Fabrice, COLLI, Maikel L, CNOP, Miriam, IGOILLO ESTEVE, Mariana, CARDOZO, Alessandra K, CUNHA, Daniel A, BUGLIANI, Marco, MARCHETTI, Piero, EIZIRIK, Décio L

“…PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon-γ–Induced Pancreatic β-Cell Apoptosis Fabrice Moore 1 , Maikel L. Colli 1 , Miriam Cnop 1 , 2…”
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Cytokines Interleukin-1β and Tumor Necrosis Factor-α Regulate Different Transcriptional and Alternative Splicing Networks in Primary β-Cells by ORTIS, Fernanda, NAAMANE, Najib, EIZIRIK, Decio L, FLAMEZ, Daisy, LADRIERE, Laurence, MOORE, Fabrice, CUNHA, Daniel A, COLLI, Maikel L, THYKJAER, Thomas, THORSEN, Kasper, ØRNTOFT, Torben F

“…Cytokines Interleukin-1β and Tumor Necrosis Factor-α Regulate Different Transcriptional and Alternative Splicing Networks in Primary β-Cells Fernanda Ortis 1 ,…”
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Gene expression signatures of target tissues in type 1 diabetes, lupus erythematosus, multiple sclerosis, and rheumatoid arthritis by Szymczak, F, Colli, M L, Mamula, M J, Evans-Molina, C, Eizirik, D L

“…Autoimmune diseases are typically studied with a focus on the immune system, and less attention is paid to responses of target tissues exposed to the immune…”
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A Humanized Mouse Strain That Develops Spontaneously Immune-Mediated Diabetes by Luce, Sandrine, Guinoiseau, Sophie, Gadault, Alexis, Letourneur, Franck, Nitschke, Patrick, Bras, Marc, Vidaud, Michel, Charneau, Pierre, Larger, Etienne, Colli, Maikel L, Eizirik, Decio L, Lemonnier, François, Boitard, Christian

“…To circumvent the limitations of available preclinical models for the study of type 1 diabetes (T1D), we developed a new humanized model, the YES-RIP-hB7.1…”
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Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance by Colli, Maikel L, Nogueira, Tatiane C, Allagnat, Florent, Cunha, Daniel A, Gurzov, Esteban N, Cardozo, Alessandra K, Roivainen, Merja, Op de Beeck, Anne, Eizirik, Decio L

“…The rise in type 1 diabetes (T1D) incidence in recent decades is probably related to modifications in environmental factors. Viruses are among the putative…”
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Sonic Hedgehog pathway is upregulated in adamantinomatous craniopharyngiomas by Gomes, D C, Jamra, S A, Leal, L F, Colli, L M, Campanini, M L, Oliveira, R S, Martinelli, C E, Elias, P C L, Moreira, A C, Machado, H R, Saggioro, F, Neder, L, Castro, M, Antonini, S R

“…ObjectivesPituitary stem cells play a role in the oncogenesis of human adamantinomatous craniopharyngiomas (aCPs). We hypothesized that crosstalk between the…”
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Coxsackievirus B Tailors the Unfolded Protein Response to Favour Viral Amplification in Pancreatic β Cells by Colli, Maikel L., Paula, Flavia M., Marselli, Lorella, Marchetti, Piero, Roivainen, Merja, Eizirik, Decio L., Op de beeck, Anne

“…Type 1 diabetes (T1D) is an autoimmune disease characterized by islet inflammation and progressive pancreatic β cell destruction. The disease is triggered by a…”
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Objectives, criteria and methods for using molecular genetic data in priority setting for conservation of animal genetic resources by Boettcher, P.J, Tixier-Boichard, M, Toro, M.A, Simianer, H, Eding, H, Gandini, G, Joost, S, Garcia, D, Colli, L, Ajmone-Marsan, P

“…The genetic diversity of the world's livestock populations is decreasing, both within and across breeds. A wide variety of factors has contributed to the loss,…”
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