Search Results - "Collesi, Chiara"
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MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs
Published in Nature (London) (01-05-2019)“…Prompt coronary catheterization and revascularization have markedly improved the outcomes of myocardial infarction, but have also resulted in a growing number…”
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2
Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology
Published in EBioMedicine (01-11-2020)“…COVID-19 is a deadly pulmonary disease with peculiar characteristics, which include variable clinical course and thrombophilia. A thorough understanding of the…”
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3
Cellular TRIM33 restrains HIV-1 infection by targeting viral integrase for proteasomal degradation
Published in Nature communications (25-02-2019)“…Productive HIV-1 replication requires viral integrase (IN), which catalyzes integration of the viral genome into the host cell DNA. IN, however, is short lived…”
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4
Notch1 signaling stimulates proliferation of immature cardiomyocytes
Published in The Journal of cell biology (06-10-2008)“…The identification of the molecular mechanisms controlling cardiomyocyte proliferation during the embryonic, fetal, and early neonatal life appears of…”
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5
Recruitment of Endophilin to Clathrin-Coated Pit Necks Is Required for Efficient Vesicle Uncoating after Fission
Published in Neuron (Cambridge, Mass.) (17-11-2011)“…Endophilin is a membrane-binding protein with curvature-generating and -sensing properties that participates in clathrin-dependent endocytosis of synaptic…”
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6
Common Regulatory Pathways Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation
Published in Cell reports (Cambridge) (28-05-2019)“…Loss of functional cardiomyocytes is a major determinant of heart failure after myocardial infarction. Previous high throughput screening studies have…”
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7
SARS-CoV-2, myocardial injury and inflammation: insights from a large clinical and autopsy study
Published in Clinical research in cardiology (01-11-2021)“…Objective Despite growing evidence about myocardial injury in hospitalized COronaVIrus Disease 2019 (COVID-19) patients, the mechanism behind this injury is…”
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8
Selective Activity-Dependent Requirement for Dynamin 1 in Synaptic Vesicle Endocytosis
Published in Science (American Association for the Advancement of Science) (27-04-2007)“…Dynamin 1 is a neuron-specific guanosine triphosphatase thought to be critically required for the fission reaction of synaptic vesicle endocytosis…”
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Cell- and Stimulus-Dependent Heterogeneity of Synaptic Vesicle Endocytic Recycling Mechanisms Revealed by Studies of Dynamin 1-Null Neurons
Published in Proceedings of the National Academy of Sciences - PNAS (12-02-2008)“…Mice lacking expression of dynamin 1, a GTPase implicated in the fission reaction of synaptic vesicle endocytosis, fail to thrive and exhibit severe…”
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10
Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice
Published in Proceedings of the National Academy of Sciences - PNAS (18-08-2009)“…Epsins are endocytic adaptors with putative functions in general aspects of clathrin-mediated endocytosis as well as in the internalization of specific…”
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11
Engineered heart tissue maturation inhibits cardiomyocyte proliferative response to cryoinjury
Published in Journal of tissue engineering (01-01-2023)“…The cellular and molecular mechanisms that are responsible for the poor regenerative capacity of the adult heart after myocardial infarction (MI) are still…”
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12
A splicing variant of the RON transcript induces constitutive tyrosine kinase activity and an invasive phenotype
Published in Molecular and Cellular Biology (01-10-1996)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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13
Persistent SARS‐CoV‐2 infection in patients seemingly recovered from COVID‐19
Published in The Journal of pathology (01-03-2023)“…SARS‐CoV‐2 infection is clinically heterogeneous, ranging from asymptomatic to deadly. A few patients with COVID‐19 appear to recover from acute viral…”
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14
Molecular tools to detect the activation of key signalling pathways driving cardiomyocyte proliferation
Published in Journal of molecular and cellular cardiology (31-12-2022)Get full text
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15
Gene transfer to promote cardiac regeneration
Published in Critical reviews in clinical laboratory sciences (01-12-2016)“…There is an impelling need to develop new therapeutic strategies for patients with myocardial infarction and heart failure. Leading from the large quantity of…”
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Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia
Published in Nature (London) (03-06-2021)“…COVID-19 is a disease with unique characteristics that include lung thrombosis 1 , frequent diarrhoea 2 , abnormal activation of the inflammatory response 3…”
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17
Microsurgical arterovenous loops and biological templates: A novel in vivo chamber for tissue engineering
Published in Microsurgery (2007)“…Background: Microsurgical tissue engineering is an emerging topic in regenerative medicine. Here we describe a new microsurgical model of bioengineering in…”
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18
Haemorrhage of human foetal cortex associated with SARS-CoV-2 infection
Published in Brain (London, England : 1878) (01-03-2023)“…Abstract Maternal viral infection and immune response are known to increase the risk of altered development of the foetal brain. Given the ongoing global…”
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Lung damage in SARS-CoV-2 patients: An autopsy study in the era of vaccination
Published in European journal of clinical investigation (29-09-2024)“…The contribution of SARS-CoV-2 infection on lung damage and the effect of vaccination on either containing the number of deaths or mitigating lung damage has…”
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20
Epigenetic Modification at Notch Responsive Promoters Blunts Efficacy of Inducing Notch Pathway Reactivation After Myocardial Infarction
Published in Circulation research (12-09-2014)“…RATIONALE:The Notch pathway plays a key role in stimulating mammalian cardiomyocyte proliferation during development and in the early postnatal life; in adult…”
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